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6CDS
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BU of 6cds by Molmil
Human neurofibromin 2/merlin/schwannomin residues 1-339 in complex with PIP2
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Merlin, ...
Authors:Chinthalapudi, K, Sharff, A.J, Bricogne, G, Izard, T.
Deposit date:2018-02-09
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2.
Nat Commun, 9, 2018
6D2Q
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BU of 6d2q by Molmil
Crystal structure of the FERM domain of zebrafish FARP1
Descriptor: FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
Authors:Kuo, Y.C, Zhang, X.
Deposit date:2018-04-13
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Structural analyses of FERM domain-mediated membrane localization of FARP1.
Sci Rep, 8, 2018
2YVC
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BU of 2yvc by Molmil
Crystal structure of the Radixin FERM domain complexed with the NEP cytoplasmic tail
Descriptor: Neprilysin, Radixin
Authors:Terawaki, S, Kitano, K, Hakoshima, T.
Deposit date:2007-04-11
Release date:2007-04-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for type II membrane protein binding by ERM proteins revealed by the radixin-neutral endopeptidase 24.11 (NEP) complex
J.Biol.Chem., 282, 2007
6D21
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BU of 6d21 by Molmil
Crystal structure of the FERM domain of zebrafish FARP2
Descriptor: FERM, RhoGEF and pleckstrin domain protein 2
Authors:Kuo, Y.C, Zhang, X.
Deposit date:2018-04-12
Release date:2018-07-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Structural analyses of FERM domain-mediated membrane localization of FARP1.
Sci Rep, 8, 2018
6D2K
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BU of 6d2k by Molmil
Crystal structure of the FERM domain of mouse FARP2
Descriptor: FERM, ARHGEF and pleckstrin domain-containing protein 2
Authors:He, X, Zhang, X.
Deposit date:2018-04-13
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural analyses of FERM domain-mediated membrane localization of FARP1.
Sci Rep, 8, 2018
2ZPY
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BU of 2zpy by Molmil
Crystal structure of the mouse radxin FERM domain complexed with the mouse CD44 cytoplasmic peptide
Descriptor: CD44 antigen, Radixin
Authors:Mori, T, Kitano, K, Terawaki, S, Maesaki, R, Fukami, Y, Hakoshima, T.
Deposit date:2008-07-31
Release date:2008-08-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for CD44 recognition by ERM proteins
J.Biol.Chem., 283, 2008
3WA0
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BU of 3wa0 by Molmil
Crystal structure of merlin complexed with DCAF1/VprBP
Descriptor: Merlin, Protein VPRBP
Authors:Mori, T, Gotoh, S, Shirakawa, M, Hakoshima, T.
Deposit date:2013-04-20
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural basis of DDB1-and-Cullin 4-associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44-mediated inhibition of merlin suppression of DCAF1 function.
Genes Cells, 19, 2014
3X23
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BU of 3x23 by Molmil
Radixin complex
Descriptor: Peptide from Matrix metalloproteinase-14, Radixin
Authors:Terawaki, S, Kitano, K, Aoyama, M, Mori, T, Hakoshima, T.
Deposit date:2014-12-09
Release date:2015-10-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.396 Å)
Cite:MT1-MMP recognition by ERM proteins and its implication in CD44 shedding
Genes Cells, 20, 2015
3ZDT
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BU of 3zdt by Molmil
Crystal structure of basic patch mutant FAK FERM domain FAK31- 405 K216A, K218A, R221A, K222A
Descriptor: FOCAL ADHESION KINASE 1
Authors:Goni, G.M, Epifano, C, Boskovic, J, Camacho-Artacho, M, Zhou, J, Martin, M.T, Eck, M.J, Kremer, L, Graeter, F, Gervasio, F.L, Perez-Moreno, M, Lietha, D.
Deposit date:2012-11-30
Release date:2012-12-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Phosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes.
Proc.Natl.Acad.Sci.USA, 111, 2014
3AU5
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BU of 3au5 by Molmil
Structure of the human myosin-X MyTH4-FERM cassette
Descriptor: Myosin-X
Authors:Hirano, Y, Takahashi, A, Hakoshima, T.
Deposit date:2011-01-28
Release date:2011-07-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain
Embo J., 30, 2011
3AU4
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BU of 3au4 by Molmil
Structure of the human myosin-X MyTH4-FERM cassette bound to its specific cargo, DCC
Descriptor: Myosin-X, Netrin receptor DCC
Authors:Hirano, Y, Hatano, T, Hakoshima, T.
Deposit date:2011-01-28
Release date:2011-07-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain
Embo J., 30, 2011
1EF1
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BU of 1ef1 by Molmil
CRYSTAL STRUCTURE OF THE MOESIN FERM DOMAIN/TAIL DOMAIN COMPLEX
Descriptor: MOESIN, SULFATE ION
Authors:Pearson, M.A, Reczek, D, Bretscher, A, Karplus, P.A.
Deposit date:2000-02-04
Release date:2000-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain.
Cell(Cambridge,Mass.), 101, 2000
1E5W
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BU of 1e5w by Molmil
Structure of isolated FERM domain and first long helix of moesin
Descriptor: MOESIN
Authors:Edwards, S.D, Keep, N.H.
Deposit date:2000-08-03
Release date:2001-06-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The 2.7 A Crystal Structure of the Activated Ferm Domain of Moesin: An Analysis of Structural Changes on Activation
Biochemistry, 40, 2001
4CYE
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BU of 4cye by Molmil
Crystal structure of avian FAK FERM domain FAK31-405 at 3.2A
Descriptor: FOCAL ADHESION KINASE 1
Authors:Goni, G.M, Epifano, C, Boskovic, J, Camacho-Artacho, M, Zhou, J, Martin, M.T, Eck, M.J, Kremer, L, Graeter, F, Gervasio, F.L, Perez-Moreno, M, Lietha, D.
Deposit date:2014-04-10
Release date:2014-04-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Phosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes.
Proc.Natl.Acad.Sci.USA, 111, 2014
1GG3
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BU of 1gg3 by Molmil
CRYSTAL STRUCTURE OF THE PROTEIN 4.1R MEMBRANE BINDING DOMAIN
Descriptor: ERYTHROID MEMBRANE PROTEIN 4.1R
Authors:Han, B.G.
Deposit date:2000-07-11
Release date:2001-01-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization.
Nat.Struct.Biol., 7, 2000
1GC6
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BU of 1gc6 by Molmil
CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE
Descriptor: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, RADIXIN
Authors:Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T.
Deposit date:2000-07-21
Release date:2000-09-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
1GC7
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BU of 1gc7 by Molmil
CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN
Descriptor: RADIXIN
Authors:Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T.
Deposit date:2000-07-21
Release date:2000-09-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
1H4R
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BU of 1h4r by Molmil
Crystal Structure of the FERM domain of Merlin, the Neurofibromatosis 2 Tumor Suppressor Protein.
Descriptor: MERLIN, SULFATE ION
Authors:Cooper, D.R, Kang, B.S, Sheffield, P, Devedjiev, Y, Derewenda, Z.S.
Deposit date:2001-05-14
Release date:2002-01-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of the Ferm Domain of Merlin, the Neurofibromatosis Type 2 Gene Product.
Acta Crystallogr.,Sect.D, 58, 2002
4EKU
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BU of 4eku by Molmil
Crystal Structure of FERM Domain of Proline-rich Tyrosine Kinase 2
Descriptor: Protein-tyrosine kinase 2-beta
Authors:Savarimuthu, B, Li, R, Wang, Y.
Deposit date:2012-04-09
Release date:2012-04-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal Structure of the Ferm Domain of Proline-rich Tyrosine Kinase 2
To be Published
1ISN
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BU of 1isn by Molmil
Crystal structure of merlin FERM domain
Descriptor: merlin
Authors:Shimizu, T, Seto, A, Maita, N, Hamada, K, Tsukita, S, Tsukita, S, Hakoshima, T.
Deposit date:2001-12-13
Release date:2002-04-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain.
J.Biol.Chem., 277, 2002
2AEH
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BU of 2aeh by Molmil
Focal adhesion kinase 1
Descriptor: Focal adhesion kinase 1
Authors:Ceccarelli, D.F, Song, H.K, Poy, F, Schaller, M.D, Eck, M.J.
Deposit date:2005-07-22
Release date:2005-10-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Crystal Structure of the FERM Domain of Focal Adhesion Kinase
J.Biol.Chem., 281, 2006
2AL6
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BU of 2al6 by Molmil
FERM domain of Focal Adhesion Kinase
Descriptor: Focal adhesion kinase 1
Authors:Ceccarelli, D.F, Song, H.K, Poy, F, Schaller, M.D, Eck, M.J.
Deposit date:2005-08-04
Release date:2005-10-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure of the FERM Domain of Focal Adhesion Kinase
J.Biol.Chem., 281, 2006
1J19
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BU of 1j19 by Molmil
Crystal structure of the radxin FERM domain complexed with the ICAM-2 cytoplasmic peptide
Descriptor: 16-mer peptide from Intercellular adhesion molecule-2, radixin
Authors:Hamada, K, Shimizu, T, Yonemura, S, Tsukita, S, Tsukita, S, Hakoshima, T.
Deposit date:2002-12-02
Release date:2003-03-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex
EMBO J., 22, 2003
2D10
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BU of 2d10 by Molmil
Crystal structure of the Radixin FERM domain complexed with the NHERF-1 C-terminal tail peptide
Descriptor: Ezrin-radixin-moesin binding phosphoprotein 50, Radixin
Authors:Terawaki, S, Maesaki, R, Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
2D11
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BU of 2d11 by Molmil
Crystal structure of the Radixin FERM domain complexed with the NHERF-2 C-terminal tail peptide
Descriptor: Na(+)/H(+) exchange regulatory cofactor NHE-RF2, Radixin
Authors:Terawaki, S, Maesaki, R, Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006

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