6CDS
| Human neurofibromin 2/merlin/schwannomin residues 1-339 in complex with PIP2 | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Merlin, ... | Authors: | Chinthalapudi, K, Sharff, A.J, Bricogne, G, Izard, T. | Deposit date: | 2018-02-09 | Release date: | 2018-07-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2. Nat Commun, 9, 2018
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6D2Q
| Crystal structure of the FERM domain of zebrafish FARP1 | Descriptor: | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | Authors: | Kuo, Y.C, Zhang, X. | Deposit date: | 2018-04-13 | Release date: | 2018-07-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Structural analyses of FERM domain-mediated membrane localization of FARP1. Sci Rep, 8, 2018
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2YVC
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6D21
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6D2K
| Crystal structure of the FERM domain of mouse FARP2 | Descriptor: | FERM, ARHGEF and pleckstrin domain-containing protein 2 | Authors: | He, X, Zhang, X. | Deposit date: | 2018-04-13 | Release date: | 2018-07-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural analyses of FERM domain-mediated membrane localization of FARP1. Sci Rep, 8, 2018
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2ZPY
| Crystal structure of the mouse radxin FERM domain complexed with the mouse CD44 cytoplasmic peptide | Descriptor: | CD44 antigen, Radixin | Authors: | Mori, T, Kitano, K, Terawaki, S, Maesaki, R, Fukami, Y, Hakoshima, T. | Deposit date: | 2008-07-31 | Release date: | 2008-08-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for CD44 recognition by ERM proteins J.Biol.Chem., 283, 2008
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3WA0
| Crystal structure of merlin complexed with DCAF1/VprBP | Descriptor: | Merlin, Protein VPRBP | Authors: | Mori, T, Gotoh, S, Shirakawa, M, Hakoshima, T. | Deposit date: | 2013-04-20 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Structural basis of DDB1-and-Cullin 4-associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44-mediated inhibition of merlin suppression of DCAF1 function. Genes Cells, 19, 2014
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3X23
| Radixin complex | Descriptor: | Peptide from Matrix metalloproteinase-14, Radixin | Authors: | Terawaki, S, Kitano, K, Aoyama, M, Mori, T, Hakoshima, T. | Deposit date: | 2014-12-09 | Release date: | 2015-10-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.396 Å) | Cite: | MT1-MMP recognition by ERM proteins and its implication in CD44 shedding Genes Cells, 20, 2015
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3ZDT
| Crystal structure of basic patch mutant FAK FERM domain FAK31- 405 K216A, K218A, R221A, K222A | Descriptor: | FOCAL ADHESION KINASE 1 | Authors: | Goni, G.M, Epifano, C, Boskovic, J, Camacho-Artacho, M, Zhou, J, Martin, M.T, Eck, M.J, Kremer, L, Graeter, F, Gervasio, F.L, Perez-Moreno, M, Lietha, D. | Deposit date: | 2012-11-30 | Release date: | 2012-12-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Phosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes. Proc.Natl.Acad.Sci.USA, 111, 2014
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3AU5
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3AU4
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1EF1
| CRYSTAL STRUCTURE OF THE MOESIN FERM DOMAIN/TAIL DOMAIN COMPLEX | Descriptor: | MOESIN, SULFATE ION | Authors: | Pearson, M.A, Reczek, D, Bretscher, A, Karplus, P.A. | Deposit date: | 2000-02-04 | Release date: | 2000-05-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain. Cell(Cambridge,Mass.), 101, 2000
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1E5W
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4CYE
| Crystal structure of avian FAK FERM domain FAK31-405 at 3.2A | Descriptor: | FOCAL ADHESION KINASE 1 | Authors: | Goni, G.M, Epifano, C, Boskovic, J, Camacho-Artacho, M, Zhou, J, Martin, M.T, Eck, M.J, Kremer, L, Graeter, F, Gervasio, F.L, Perez-Moreno, M, Lietha, D. | Deposit date: | 2014-04-10 | Release date: | 2014-04-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Phosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes. Proc.Natl.Acad.Sci.USA, 111, 2014
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1GG3
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1GC6
| CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, RADIXIN | Authors: | Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T. | Deposit date: | 2000-07-21 | Release date: | 2000-09-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. EMBO J., 19, 2000
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1GC7
| CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN | Descriptor: | RADIXIN | Authors: | Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T. | Deposit date: | 2000-07-21 | Release date: | 2000-09-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain. EMBO J., 19, 2000
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1H4R
| Crystal Structure of the FERM domain of Merlin, the Neurofibromatosis 2 Tumor Suppressor Protein. | Descriptor: | MERLIN, SULFATE ION | Authors: | Cooper, D.R, Kang, B.S, Sheffield, P, Devedjiev, Y, Derewenda, Z.S. | Deposit date: | 2001-05-14 | Release date: | 2002-01-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Structure of the Ferm Domain of Merlin, the Neurofibromatosis Type 2 Gene Product. Acta Crystallogr.,Sect.D, 58, 2002
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4EKU
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1ISN
| Crystal structure of merlin FERM domain | Descriptor: | merlin | Authors: | Shimizu, T, Seto, A, Maita, N, Hamada, K, Tsukita, S, Tsukita, S, Hakoshima, T. | Deposit date: | 2001-12-13 | Release date: | 2002-04-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain. J.Biol.Chem., 277, 2002
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2AEH
| Focal adhesion kinase 1 | Descriptor: | Focal adhesion kinase 1 | Authors: | Ceccarelli, D.F, Song, H.K, Poy, F, Schaller, M.D, Eck, M.J. | Deposit date: | 2005-07-22 | Release date: | 2005-10-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Crystal Structure of the FERM Domain of Focal Adhesion Kinase J.Biol.Chem., 281, 2006
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2AL6
| FERM domain of Focal Adhesion Kinase | Descriptor: | Focal adhesion kinase 1 | Authors: | Ceccarelli, D.F, Song, H.K, Poy, F, Schaller, M.D, Eck, M.J. | Deposit date: | 2005-08-04 | Release date: | 2005-10-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal Structure of the FERM Domain of Focal Adhesion Kinase J.Biol.Chem., 281, 2006
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1J19
| Crystal structure of the radxin FERM domain complexed with the ICAM-2 cytoplasmic peptide | Descriptor: | 16-mer peptide from Intercellular adhesion molecule-2, radixin | Authors: | Hamada, K, Shimizu, T, Yonemura, S, Tsukita, S, Tsukita, S, Hakoshima, T. | Deposit date: | 2002-12-02 | Release date: | 2003-03-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex EMBO J., 22, 2003
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2D10
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2D11
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