4ESM
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![BU of 4esm by Molmil](/molmil-images/mine/4esm) | Crystallographic structure of phenylalanine hydroxylase from Chromobacterium violaceum Y155A mutation | Descriptor: | COBALT (II) ION, Phenylalanine-4-hydroxylase | Authors: | Ronau, J.A, Paul, L.P, Corn, I.R, Wagner, K.T, Abu-Omar, M.M, Das, C. | Deposit date: | 2012-04-23 | Release date: | 2013-05-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | An additional substrate binding site in a bacterial phenylalanine hydroxylase. Eur.Biophys.J., 42, 2013
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4ETL
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![BU of 4etl by Molmil](/molmil-images/mine/4etl) | Crystallographic structure of phenylalanine hydroxylase from Chromobacterium violaceum F258A mutation | Descriptor: | COBALT (II) ION, Phenylalanine-4-hydroxylase | Authors: | Ronau, J.A, Paul, L.P, Corn, I.R, Wagner, K.T, Abu-Omar, M.M, Das, C. | Deposit date: | 2012-04-24 | Release date: | 2013-05-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | An additional substrate binding site in a bacterial phenylalanine hydroxylase. Eur.Biophys.J., 42, 2013
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4EUX
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![BU of 4eux by Molmil](/molmil-images/mine/4eux) | Structure of neuronal nitric oxide synthase heme domain in complex with 6-(5-(((3R,4R)-4-((6-amino-4-methylpyridin-2-yl)methyl)pyrrolidin-3-yl)oxy)pentyl)-4-methylpyridin-2-amine | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6-[5-({(3R,4R)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}oxy)pentyl]-4-methylpyridin-2-amine, ACETATE ION, ... | Authors: | Li, H, Poulos, T.L. | Deposit date: | 2012-04-25 | Release date: | 2012-07-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Selective monocationic inhibitors of neuronal nitric oxide synthase. Binding mode insights from molecular dynamics simulations. J.Am.Chem.Soc., 134, 2012
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4EWA
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![BU of 4ewa by Molmil](/molmil-images/mine/4ewa) | Study on structure and function relationships in human Pirin with Fe ion | Descriptor: | FE (III) ION, Pirin | Authors: | Liu, F, Rehmani, I, Chen, L, Fu, R, Serrano, V, Wilson, D.W, Liu, A. | Deposit date: | 2012-04-26 | Release date: | 2013-05-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Pirin is an iron-dependent redox regulator of NF-kappa B. Proc.Natl.Acad.Sci.USA, 110, 2013
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4F2H
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![BU of 4f2h by Molmil](/molmil-images/mine/4f2h) | |
4F1P
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![BU of 4f1p by Molmil](/molmil-images/mine/4f1p) | Crystal Structure of mutant S554D for ArfGAP and ANK repeat domain of ACAP1 | Descriptor: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1, SULFATE ION, ... | Authors: | Sun, F, Pang, X, Zhang, K, Ma, J, Zhou, Q. | Deposit date: | 2012-05-07 | Release date: | 2012-07-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Mechanistic insights into regulated cargo binding by ACAP1 protein J.Biol.Chem., 287, 2012
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4F8D
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![BU of 4f8d by Molmil](/molmil-images/mine/4f8d) | |
4F99
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![BU of 4f99 by Molmil](/molmil-images/mine/4f99) | Human CDC7 kinase in complex with DBF4 and nucleotide | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cell division cycle 7-related protein kinase, MAGNESIUM ION, ... | Authors: | Hughes, S, Cherepanov, P. | Deposit date: | 2012-05-18 | Release date: | 2012-10-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
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4F9B
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![BU of 4f9b by Molmil](/molmil-images/mine/4f9b) | Human CDC7 kinase in complex with DBF4 and PHA767491 | Descriptor: | 2-(pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one, Cell division cycle 7-related protein kinase, Protein DBF4 homolog A, ... | Authors: | Hughes, S, Cherepanov, P. | Deposit date: | 2012-05-18 | Release date: | 2012-10-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
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4F9C
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![BU of 4f9c by Molmil](/molmil-images/mine/4f9c) | Human CDC7 kinase in complex with DBF4 and XL413 | Descriptor: | 8-chloro-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one, Cell division cycle 7-related protein kinase, Protein DBF4 homolog A, ... | Authors: | Hughes, S, Cherepanov, P. | Deposit date: | 2012-05-18 | Release date: | 2012-10-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
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4F9A
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![BU of 4f9a by Molmil](/molmil-images/mine/4f9a) | Human CDC7 kinase in complex with DBF4 and nucleotide | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cell division cycle 7-related protein kinase, MAGNESIUM ION, ... | Authors: | Hughes, S, Cherepanov, P. | Deposit date: | 2012-05-18 | Release date: | 2012-10-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
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4FA8
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![BU of 4fa8 by Molmil](/molmil-images/mine/4fa8) | Multi-pronged modulation of cytokine signaling | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage colony-stimulating factor 1, Secreted protein BARF1, ... | Authors: | He, X, Shim, A.H. | Deposit date: | 2012-05-21 | Release date: | 2012-08-29 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Multipronged attenuation of macrophage-colony stimulating factor signaling by Epstein-Barr virus BARF1. Proc.Natl.Acad.Sci.USA, 109, 2012
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4FBI
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![BU of 4fbi by Molmil](/molmil-images/mine/4fbi) | |
4AWB
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![BU of 4awb by Molmil](/molmil-images/mine/4awb) | Crystal structure of active legumain in complex with AAN-CMK | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LEGUMAIN, MERCURY (II) ION, ... | Authors: | Dall, E, Brandstetter, H. | Deposit date: | 2012-06-01 | Release date: | 2013-06-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Mechanistic and Structural Studies on Legumain Explain its Zymogenicity, Distinct Activation Pathways, and Regulation Proc.Natl.Acad.Sci.USA, 110, 2013
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4AW9
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![BU of 4aw9 by Molmil](/molmil-images/mine/4aw9) | Crystal structure of active legumain in complex with YVAD-CMK | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACE-TYR-VAL-ALA-ASP-CHLOROMETHYLKETONE, LEGUMAIN, ... | Authors: | Dall, E, Brandstetter, H. | Deposit date: | 2012-06-01 | Release date: | 2013-06-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mechanistic and Structural Studies on Legumain Explain its Zymogenicity, Distinct Activation Pathways, and Regulation Proc.Natl.Acad.Sci.USA, 110, 2013
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4FFO
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![BU of 4ffo by Molmil](/molmil-images/mine/4ffo) | PylC in complex with phosphorylated D-ornithine | Descriptor: | (2R)-2,5-diaminopentanoyl dihydrogen phosphate, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Quitterer, F, List, A, Beck, P, Bacher, A, Groll, M. | Deposit date: | 2012-06-01 | Release date: | 2012-09-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: structure and reaction mechanism of PylC at 1.5A resolution. J.Mol.Biol., 424, 2012
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4AWA
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![BU of 4awa by Molmil](/molmil-images/mine/4awa) | Crystal structure of active legumain in complex with YVAD-CMK at pH 5.0 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LEGUMAIN, SULFATE ION, ... | Authors: | Dall, E, Brandstetter, H. | Deposit date: | 2012-06-01 | Release date: | 2013-06-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mechanistic and Structural Studies on Legumain Explain its Zymogenicity, Distinct Activation Pathways, and Regulation Proc.Natl.Acad.Sci.USA, 110, 2013
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4FFP
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![BU of 4ffp by Molmil](/molmil-images/mine/4ffp) | PylC in complex with L-lysine-Ne-D-ornithine (cocrystallized with L-lysine and D-ornithine) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, N~6~-D-ornithyl-L-lysine, ... | Authors: | Quitterer, F, List, A, Beck, P, Bacher, A, Groll, M. | Deposit date: | 2012-06-01 | Release date: | 2012-09-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: structure and reaction mechanism of PylC at 1.5A resolution. J.Mol.Biol., 424, 2012
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4FFN
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![BU of 4ffn by Molmil](/molmil-images/mine/4ffn) | PylC in complex with D-ornithine and AMPPNP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, D-ORNITHINE, MAGNESIUM ION, ... | Authors: | Quitterer, F, List, A, Beck, P, Bacher, A, Groll, M. | Deposit date: | 2012-06-01 | Release date: | 2012-09-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: structure and reaction mechanism of PylC at 1.5A resolution. J.Mol.Biol., 424, 2012
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4FFM
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![BU of 4ffm by Molmil](/molmil-images/mine/4ffm) | PylC in complex with L-lysine-Ne-D-ornithine (cocrystallized with L-lysine-Ne-D-ornithine) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Quitterer, F, List, A, Beck, P, Bacher, A, Groll, M. | Deposit date: | 2012-06-01 | Release date: | 2012-09-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: structure and reaction mechanism of PylC at 1.5A resolution. J.Mol.Biol., 424, 2012
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4FFR
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![BU of 4ffr by Molmil](/molmil-images/mine/4ffr) | SeMet-labeled PylC (remote) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PylC | Authors: | Quitterer, F, List, A, Beck, P, Bacher, A, Groll, M. | Deposit date: | 2012-06-01 | Release date: | 2012-09-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: structure and reaction mechanism of PylC at 1.5A resolution. J.Mol.Biol., 424, 2012
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4FFL
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![BU of 4ffl by Molmil](/molmil-images/mine/4ffl) | PylC in complex with L-lysine | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CARBONATE ION, ... | Authors: | Quitterer, F, List, A, Beck, P, Bacher, A, Groll, M. | Deposit date: | 2012-06-01 | Release date: | 2012-09-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: structure and reaction mechanism of PylC at 1.5A resolution. J.Mol.Biol., 424, 2012
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4FGU
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![BU of 4fgu by Molmil](/molmil-images/mine/4fgu) | Crystal structure of prolegumain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Legumain | Authors: | Dall, E, Brandstetter, H. | Deposit date: | 2012-06-05 | Release date: | 2013-07-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Mechanistic and structural studies on legumain explain its zymogenicity, distinct activation pathways, and regulation. Proc.Natl.Acad.Sci.USA, 110, 2013
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3VU3
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![BU of 3vu3 by Molmil](/molmil-images/mine/3vu3) | |
4FN3
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![BU of 4fn3 by Molmil](/molmil-images/mine/4fn3) | |