6C1G
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![BU of 6c1g by Molmil](/molmil-images/mine/6c1g) | High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V. | Deposit date: | 2018-01-04 | Release date: | 2018-01-31 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4DBP
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![BU of 4dbp by Molmil](/molmil-images/mine/4dbp) | |
6NX4
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![BU of 6nx4 by Molmil](/molmil-images/mine/6nx4) | Structure of the C-terminal Helical Repeat Domain of Eukaryotic Elongation Factor 2 Kinase (eEF-2K) | Descriptor: | Eukaryotic elongation factor 2 kinase | Authors: | Piserchio, A, Will, N, Giles, D.H, Hajredini, F, Dalby, K.N, Ghose, R. | Deposit date: | 2019-02-08 | Release date: | 2019-05-29 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Carboxy-Terminal Tandem Repeat Domain of Eukaryotic Elongation Factor 2 Kinase and Its Role in Substrate Recognition. J.Mol.Biol., 431, 2019
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3SG4
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![BU of 3sg4 by Molmil](/molmil-images/mine/3sg4) | Crystal Structure of GCaMP3-D380Y, LP(linker 2) | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | Deposit date: | 2011-06-14 | Release date: | 2012-06-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
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3SG3
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![BU of 3sg3 by Molmil](/molmil-images/mine/3sg3) | Crystal Structure of GCaMP3-D380Y | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | Deposit date: | 2011-06-14 | Release date: | 2012-06-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
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4YSM
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3SG2
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![BU of 3sg2 by Molmil](/molmil-images/mine/3sg2) | Crystal Structure of GCaMP2-T116V,D381Y | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | Deposit date: | 2011-06-14 | Release date: | 2012-06-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
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3SG6
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![BU of 3sg6 by Molmil](/molmil-images/mine/3sg6) | Crystal Structure of Dimeric GCaMP2-LIA(linker 1) | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | Deposit date: | 2011-06-14 | Release date: | 2012-06-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
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3SG7
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![BU of 3sg7 by Molmil](/molmil-images/mine/3sg7) | Crystal Structure of GCaMP3-KF(linker 1) | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | Deposit date: | 2011-06-14 | Release date: | 2012-06-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
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3SG5
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![BU of 3sg5 by Molmil](/molmil-images/mine/3sg5) | Crystal Structure of Dimeric GCaMP3-D380Y, QP(linker 1), LP(linker 2) | Descriptor: | CALCIUM ION, GLYCEROL, Myosin light chain kinase, ... | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | Deposit date: | 2011-06-14 | Release date: | 2012-06-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
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4YUQ
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![BU of 4yuq by Molmil](/molmil-images/mine/4yuq) | CDPK1 from Eimeria tenella in complex with inhibitor UW1354 | Descriptor: | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, CALCIUM ION, Calmodulin-like domain protein kinase | Authors: | Merritt, E.A. | Deposit date: | 2015-03-19 | Release date: | 2016-04-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | CDPK is a druggable target in the apicomplexan parasite Eimeria to be published
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4YZB
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![BU of 4yzb by Molmil](/molmil-images/mine/4yzb) | CDPK1 from Eimeria tenella in complex with inhibitor UW1521 | Descriptor: | 4-(6-ethoxynaphthalen-2-yl)-6-(piperazin-1-ylmethyl)-2H-indazol-3-amine, CALCIUM ION, Calmodulin-like domain protein kinase | Authors: | Merritt, E.A. | Deposit date: | 2015-03-24 | Release date: | 2016-04-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | CDPK is a druggable target in the apicomplexan parasite Eimeria to be published
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5B25
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![BU of 5b25 by Molmil](/molmil-images/mine/5b25) | Crystal structure of human PDE1B with inhibitor 3 | Descriptor: | (11R,15S)-4-{[4-(6-fluoropyridin-2-yl)phenyl]methyl}-8-methyl-5-(phenylamino)-1,3,4,8,10-pentaazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one, Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, GLYCEROL, ... | Authors: | Ida, K, Lane, W, Snell, G, Sogabe, S. | Deposit date: | 2016-01-07 | Release date: | 2016-02-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases J.Med.Chem., 59, 2016
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6SL2
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![BU of 6sl2 by Molmil](/molmil-images/mine/6sl2) | ALPHA-ACTININ FROM ENTAMOEBA HISTOLYTICA | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Calponin homology domain protein putative, ... | Authors: | Pinotsis, N, Khan, M.B, Djinovic-Carugo, K. | Deposit date: | 2019-08-18 | Release date: | 2020-08-26 | Last modified: | 2020-11-04 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Calcium modulates the domain flexibility and function of an alpha-actinin similar to the ancestral alpha-actinin. Proc.Natl.Acad.Sci.USA, 117, 2020
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6SL7
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2QG5
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![BU of 2qg5 by Molmil](/molmil-images/mine/2qg5) | Cryptosporidium parvum calcium dependent protein kinase cgd7_1840 | Descriptor: | Calcium/calmodulin-dependent protein kinase | Authors: | Lunin, V.V, Wernimont, A.K, Lew, J, Wasney, G, Kozieradzki, I, Vedadi, M, Bochkarev, A, Arrowsmith, C.H, Sundstrom, M, Weigelt, J, Edwards, A.E, Hui, R, Artz, J, Amani, M, Structural Genomics Consortium (SGC) | Deposit date: | 2007-06-28 | Release date: | 2007-09-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Cryptosporidium parvum calcium dependent protein kinase cgd7_1840 To be Published
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6V00
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![BU of 6v00 by Molmil](/molmil-images/mine/6v00) | structure of human KCNQ1-KCNE3-CaM complex | Descriptor: | CALCIUM ION, Calmodulin-1, MCherry fluorescent protein,Potassium voltage-gated channel subfamily E member 3, ... | Authors: | Mackinnon, R, Sun, J. | Deposit date: | 2019-11-16 | Release date: | 2019-12-04 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural Basis of Human KCNQ1 Modulation and Gating. Cell, 180, 2020
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6UZZ
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![BU of 6uzz by Molmil](/molmil-images/mine/6uzz) | structure of human KCNQ1-CaM complex | Descriptor: | CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1 | Authors: | Mackinnon, R, Sun, J. | Deposit date: | 2019-11-16 | Release date: | 2019-12-04 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural Basis of Human KCNQ1 Modulation and Gating. Cell, 180, 2020
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2RFA
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![BU of 2rfa by Molmil](/molmil-images/mine/2rfa) | |
6V01
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![BU of 6v01 by Molmil](/molmil-images/mine/6v01) | structure of human KCNQ1-KCNE3-CaM complex with PIP2 | Descriptor: | CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily E member 3, ... | Authors: | Mackinnon, R, Sun, J. | Deposit date: | 2019-11-18 | Release date: | 2019-12-04 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural Basis of Human KCNQ1 Modulation and Gating. Cell, 180, 2020
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1AUI
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![BU of 1aui by Molmil](/molmil-images/mine/1aui) | HUMAN CALCINEURIN HETERODIMER | Descriptor: | CALCIUM ION, FE (III) ION, SERINE/THREONINE PHOSPHATASE 2B, ... | Authors: | Kissinger, C.R, Parge, H.E, Knighton, D.R, Pelletier, L.A, Lewis, C.T, Tempczyk, A, Villafranca, J.E. | Deposit date: | 1997-08-27 | Release date: | 1997-12-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex. Nature, 378, 1995
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8BWY
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![BU of 8bwy by Molmil](/molmil-images/mine/8bwy) | In situ outer dynein arm from Chlamydomonas reinhardtii in a pre-power stroke state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Calmodulin, ... | Authors: | Zimmermann, N.E.L, Noga, A, Obbineni, J.M, Ishikawa, T. | Deposit date: | 2022-12-07 | Release date: | 2023-05-10 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (38 Å) | Cite: | ATP-induced conformational change of axonemal outer dynein arms revealed by cryo-electron tomography. Embo J., 42, 2023
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4DBQ
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![BU of 4dbq by Molmil](/molmil-images/mine/4dbq) | |
5I0I
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![BU of 5i0i by Molmil](/molmil-images/mine/5i0i) | Crystal structure of myosin X motor domain with 2IQ motifs in pre-powerstroke state | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, Calmodulin, ... | Authors: | Isabet, T, Sweeney, H.L, Houdusse, A. | Deposit date: | 2016-02-04 | Release date: | 2016-09-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | The myosin X motor is optimized for movement on actin bundles. Nat Commun, 7, 2016
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3EVP
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![BU of 3evp by Molmil](/molmil-images/mine/3evp) | crystal structure of circular-permutated EGFP | Descriptor: | Green fluorescent protein,Green fluorescent protein | Authors: | Wang, Q, Shui, B, Kotlikoff, M.I, Sondermann, H. | Deposit date: | 2008-10-13 | Release date: | 2008-12-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.453 Å) | Cite: | Structural Basis for Calcium Sensing by GCaMP2. Structure, 16, 2008
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