4YUQ

CDPK1 from Eimeria tenella in complex with inhibitor UW1354

Summary for 4YUQ

• Entry DOI: 10.2210/pdb4yuq/pdb
• Related: 4ysj 4ysm
• Descriptor: Calmodulin-like domain protein kinase, CALCIUM ION, 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (3 entities in total)
• Functional Keywords: serine/threonine protein kinase, transferase, calcium-binding, atp-binding, bumped kinase inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Eimeria tenella (Coccidian parasite)
• Total number of polymer chains: 2
• Total formula weight: 112296.36

Authors

Merritt, E.A. (deposition date: 2015-03-19, release date: 2016-04-06, Last modification date: 2023-09-27)

• Primary citation: Ojo, K.K.,Vidadala, R.,Maly, D.J.,Van Voorhis, W.C.,Merritt, E.A.; CDPK is a druggable target in the apicomplexan parasite Eimeria; to be published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)