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7QXP
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BU of 7qxp by Molmil
Proteasome-ZFAND5 Complex Z+B state
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhu, Y, Lu, Y.
Deposit date:2022-01-26
Release date:2023-02-08
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular mechanism for activation of the 26S proteasome by ZFAND5.
Mol.Cell, 83, 2023
7QXW
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BU of 7qxw by Molmil
Proteasome-ZFAND5 Complex Z+D state
Descriptor: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ...
Authors:Zhu, Y, Lu, Y.
Deposit date:2022-01-27
Release date:2023-02-08
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Molecular mechanism for activation of the 26S proteasome by ZFAND5.
Mol.Cell, 83, 2023
7QYA
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BU of 7qya by Molmil
Proteasome-ZFAND5 Complex Z-B state
Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
Authors:Zhu, Y, Lu, Y.
Deposit date:2022-01-27
Release date:2023-02-08
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Molecular mechanism for activation of the 26S proteasome by ZFAND5.
Mol.Cell, 83, 2023
6RFR
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BU of 6rfr by Molmil
Cryo-EM structure of respiratory complex I from Yarrowia lipolytica at 3.2 A resolution
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), ...
Authors:Parey, K, Vonck, J.
Deposit date:2019-04-16
Release date:2019-12-11
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease.
Sci Adv, 5, 2019
6OVJ
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BU of 6ovj by Molmil
NMR structure of truncated alpha conotoxin SII: Ile-SII(3-14)
Descriptor: Alpha-conotoxin S2
Authors:Chin, Y.K.-Y, Wilhelm, P, Alewood, P.F.
Deposit date:2019-05-08
Release date:2020-05-06
Last modified:2023-10-11
Method:SOLUTION NMR
Cite:Cysteine-Rich alpha-Conotoxin SII Displays Novel Interactions at the Muscle Nicotinic Acetylcholine Receptor.
Acs Chem Neurosci, 13, 2022
5KEW
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BU of 5kew by Molmil
Vibrio parahaemolyticus VtrA/VtrC complex bound to the bile salt taurodeoxycholate
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, SULFATE ION, ...
Authors:Tomchick, D.R, Orth, K, Rivera-Cancel, G.
Deposit date:2016-06-10
Release date:2016-07-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Bile salt receptor complex activates a pathogenic type III secretion system.
Elife, 5, 2016
5JK6
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BU of 5jk6 by Molmil
Phenylalanine hydroxylase from dictyostelium - apo form
Descriptor: FE (III) ION, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID), Phenylalanine-4-hydroxylase
Authors:Zhuang, N, Lee, K.H.
Deposit date:2016-04-26
Release date:2017-04-26
Method:X-RAY DIFFRACTION (2.072 Å)
Cite:Phenylalanine hydroxylase from dictyostelium - apo form
To Be Published
3UVR
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BU of 3uvr by Molmil
Human p38 MAP Kinase in Complex with KM064
Descriptor: 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-{3-[(5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino]phenyl}urea, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
Authors:Richters, A, Mayer-Wrangowski, S.C, Gruetter, C, Rauh, D.
Deposit date:2011-11-30
Release date:2012-12-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:

5IT1
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BU of 5it1 by Molmil
Streptomyces peucetius CYP105P2 complex with biphenyl compound
Descriptor: 4,4'-PROPANE-2,2-DIYLDIPHENOL, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450
Authors:Lee, C.W, Lee, J.H.
Deposit date:2016-03-16
Release date:2016-06-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Cytochrome P450 (CYP105P2) from Streptomyces peucetius and Its Conformational Changes in Response to Substrate Binding
Int J Mol Sci, 17, 2016
5L4K
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BU of 5l4k by Molmil
The human 26S proteasome lid
Descriptor: 26S proteasome complex subunit DSS1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
Authors:Schweitzer, A, Aufderheide, A, Rudack, T, Beck, F.
Deposit date:2016-05-25
Release date:2016-09-07
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the human 26S proteasome at a resolution of 3.9 angstrom.
Proc.Natl.Acad.Sci.USA, 113, 2016
6MA7
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BU of 6ma7 by Molmil
Human CYP3A4 bound to an inhibitor fluconazole
Descriptor: 1,2-ETHANEDIOL, 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, Cytochrome P450 3A4, ...
Authors:Sevrioukova, I.F.
Deposit date:2018-08-26
Release date:2019-01-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Interaction of Human Drug-Metabolizing CYP3A4 with Small Inhibitory Molecules.
Biochemistry, 58, 2019
8V84
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BU of 8v84 by Molmil
60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map)
Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
Authors:Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
Deposit date:2023-12-04
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
8V83
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BU of 8v83 by Molmil
60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map)
Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
Authors:Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
Deposit date:2023-12-04
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
6MA8
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BU of 6ma8 by Molmil
Human CYP3A4 bound to PMSF
Descriptor: 1,2-ETHANEDIOL, Cytochrome P450 3A4, DIMETHYL SULFOXIDE, ...
Authors:Sevrioukova, I.F.
Deposit date:2018-08-26
Release date:2019-01-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Interaction of Human Drug-Metabolizing CYP3A4 with Small Inhibitory Molecules.
Biochemistry, 58, 2019
7SD1
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BU of 7sd1 by Molmil
Crystal structure of SHOC2
Descriptor: Leucine-rich repeat protein SHOC-2
Authors:Liau, N.P.D, Hymowitz, S.G, Sudhamsu, J.
Deposit date:2021-09-29
Release date:2022-04-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structural basis for SHOC2 modulation of RAS signalling.
Nature, 609, 2022
8WDV
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BU of 8wdv by Molmil
Photosynthetic LH1-RC complex from the purple sulfur bacterium Allochromatium vinosum purified by Ca2+-DEAE
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, Antenna complex alpha/beta subunit, ...
Authors:Tani, K, Kanno, R, Harada, A, Kobayashi, A, Minamino, A, Nakamura, N, Ji, X.-C, Purba, E.R, Hall, M, Yu, L.-J, Madigan, M.T, Mizoguchi, A, Iwasaki, K, Humbel, B.M, Kimura, Y, Wang-Otomo, Z.-Y.
Deposit date:2023-09-16
Release date:2024-02-21
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.24 Å)
Cite:High-resolution structure and biochemical properties of the LH1-RC photocomplex from the model purple sulfur bacterium, Allochromatium vinosum.
Commun Biol, 7, 2024
1NU1
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BU of 1nu1 by Molmil
Crystal Structure of Mitochondrial Cytochrome bc1 Complexed with 2-nonyl-4-hydroxyquinoline N-oxide (NQNO)
Descriptor: 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE, Cytochrome b, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Gao, X, Wen, X, Esser, L, Quinn, B, Yu, L, Yu, C.-A, Xia, D.
Deposit date:2003-01-30
Release date:2003-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site
Biochemistry, 42, 2003
6T15
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BU of 6t15 by Molmil
The III2-IV(5B)1 respiratory supercomplex from S. cerevisiae
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CARDIOLIPIN, COPPER (II) ION, ...
Authors:Marechal, A, Pinotsis, N, Hartley, A.
Deposit date:2019-10-03
Release date:2020-04-22
Last modified:2020-05-06
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes.
Proc.Natl.Acad.Sci.USA, 117, 2020
6MA6
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BU of 6ma6 by Molmil
Human CYP3A4 bound to an inhibitor metyrapone
Descriptor: 1,2-ETHANEDIOL, Cytochrome P450 3A4, GLYCEROL, ...
Authors:Sevrioukova, I.F.
Deposit date:2018-08-26
Release date:2019-01-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.182 Å)
Cite:Interaction of Human Drug-Metabolizing CYP3A4 with Small Inhibitory Molecules.
Biochemistry, 58, 2019
5JK8
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BU of 5jk8 by Molmil
Phenylalanine hydroxylase from dictyostelium - BH2, norleucine complex
Descriptor: 7,8-DIHYDROBIOPTERIN, FE (III) ION, NORLEUCINE, ...
Authors:Zhuang, N, Lee, K.H.
Deposit date:2016-04-26
Release date:2017-05-03
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Phenylalanine hydroxylase from dictyostelium - BH2, norleucine complex
To Be Published
7S0V
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BU of 7s0v by Molmil
The role of an Asp-Asp pair in the structure, function and inhibition of CTX-M Class A Beta-lactamase
Descriptor: 3-(1H-pyrazol-1-yl)-N-[3-(1H-tetrazol-5-yl)phenyl]-5-(trifluoromethyl)benzamide, Beta-lactamase
Authors:Kemp, M.T, Chen, Y.
Deposit date:2021-08-31
Release date:2021-11-10
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mutation of the conserved Asp-Asp pair impairs the structure, function, and inhibition of CTX-M Class A beta-lactamase.
Febs Lett., 595, 2021
8J07
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BU of 8j07 by Molmil
96nm repeat of human respiratory doublet microtubule and associated axonemal complexes
Descriptor: ACTA2, Axonemal dynein light intermediate polypeptide 1, Calaxin, ...
Authors:Gui, M, Brown, A.
Deposit date:2023-04-09
Release date:2023-07-26
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Axonemal structures reveal mechanoregulatory and disease mechanisms.
Nature, 618, 2023
1NTZ
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BU of 1ntz by Molmil
Crystal Structure of Mitochondrial Cytochrome bc1 Complex Bound with Ubiquinone
Descriptor: Cytochrome b, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Gao, X, Wen, X, Esser, L, Quinn, B, Yu, L, Yu, C.-A, Xia, D.
Deposit date:2003-01-30
Release date:2003-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site
Biochemistry, 42, 2003
5JK5
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BU of 5jk5 by Molmil
Phenylalanine hydroxylase from dictyostelium - BH2 complex
Descriptor: 7,8-DIHYDROBIOPTERIN, FE (III) ION, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID), ...
Authors:Zhuang, N, Lee, K.H.
Deposit date:2016-04-26
Release date:2017-04-26
Method:X-RAY DIFFRACTION (2.071 Å)
Cite:Phenylalanine hydroxylase from dictyostelium - BH2 complex
To Be Published
1NTK
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BU of 1ntk by Molmil
Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Antimycin A1
Descriptor: Cytochrome b, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Gao, X, Wen, X, Esser, L, Quinn, B, Yu, L, Yu, C.-A, Xia, D.
Deposit date:2003-01-30
Release date:2003-10-07
Last modified:2016-03-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site
Biochemistry, 42, 2003

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