6MA8
Human CYP3A4 bound to PMSF
Summary for 6MA8
| Entry DOI | 10.2210/pdb6ma8/pdb |
| Descriptor | Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, GLYCEROL, ... (7 entities in total) |
| Functional Keywords | oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, cyp3a4, oxidoreductase/oxidoreductase inhibitor |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 57245.29 |
| Authors | Sevrioukova, I.F. (deposition date: 2018-08-26, release date: 2019-01-16, Last modification date: 2023-10-11) |
| Primary citation | Sevrioukova, I. Interaction of Human Drug-Metabolizing CYP3A4 with Small Inhibitory Molecules. Biochemistry, 58:930-939, 2019 Cited by PubMed: 30676743DOI: 10.1021/acs.biochem.8b01221 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
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