7SD1

Crystal structure of SHOC2

Summary for 7SD1

Entry DOI	10.2210/pdb7sd1/pdb
Descriptor	Leucine-rich repeat protein SHOC-2 (1 entity in total)
Functional Keywords	pp1c, ras, scaffold, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	260627.88
Authors	Liau, N.P.D.,Hymowitz, S.G.,Sudhamsu, J. (deposition date: 2021-09-29, release date: 2022-04-20, Last modification date: 2023-10-18)
Primary citation	Liau, N.P.D.,Johnson, M.C.,Izadi, S.,Gerosa, L.,Hammel, M.,Bruning, J.M.,Wendorff, T.J.,Phung, W.,Hymowitz, S.G.,Sudhamsu, J. Structural basis for SHOC2 modulation of RAS signalling. Nature, 609:400-407, 2022 Cited by PubMed: 35768504 DOI: 10.1038/s41586-022-04838-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.19 Å)

Structure validation