PDB: 27116 resultsInfo pagesStatus searchChemie searchBIRD

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4J73	Crystal structure of beta'-COP/p25 complex Descriptor: Coatomer subunit beta', Transmembrane emp24 domain-containing protein 9 Authors: Ma, W, Goldberg, J. Deposit date: 2013-02-12 Release date: 2013-03-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.439 Å) Cite: Rules for the recognition of dilysine retrieval motifs by coatomer. Embo J., 32, 2013
4J82	Crystal structure of beta'-COP/Insig-2 complex Descriptor: Coatomer subunit beta', INSIG2 Authors: Ma, W, Goldberg, J. Deposit date: 2013-02-14 Release date: 2013-03-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.461 Å) Cite: Rules for the recognition of dilysine retrieval motifs by coatomer. Embo J., 32, 2013
6XBM	Structure of human SMO-Gi complex with 24(S),25-EC Descriptor: 17-[3-(3,3-DIMETHYL-OXIRANYL)-1-METHYL-PROPYL]-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYC LOPENTA[A]PHENANTHREN-3-OL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Qi, X, Long, T, Li, X. Deposit date: 2020-06-06 Release date: 2020-09-30 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.14 Å) Cite: Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling. Nat.Chem.Biol., 16, 2020
5KQQ	Crystal structure of the W153F variant of catalase-peroxidase from B. pseudomallei treated Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Catalase-peroxidase, OXYGEN MOLECULE, ... Authors: Loewen, P.C. Deposit date: 2016-07-06 Release date: 2017-07-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Structure of the W153F variant of catalase-peroxidase of B. pseudomallei at 1.87 Angstroms. To be published
6XN6	ScoE with the CABA substrate bound and His299 and Arg157 flipped out Descriptor: (3~{R})-3-(2-hydroxy-2-oxoethylamino)butanoic acid, ACETATE ION, CHLORIDE ION, ... Authors: Jonnalagadda, R, Drennan, C.L. Deposit date: 2020-07-02 Release date: 2021-01-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Biochemical and crystallographic investigations into isonitrile formation by a nonheme iron-dependent oxidase/decarboxylase. J.Biol.Chem., 296, 2021
7QP7	Structure of the human 48S initiation complex in closed state (h48S AUG closed) Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. Deposit date: 2022-01-03 Release date: 2022-05-11 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
7QP6	Structure of the human 48S initiation complex in open state (h48S AUG open) Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. Deposit date: 2022-01-03 Release date: 2022-05-11 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
6XBL	Structure of human SMO-Gi complex with SAG Descriptor: 3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-{[3-(pyridin-4-yl)phenyl]methyl}-1-benzothiophene-2-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Qi, X, Li, X. Deposit date: 2020-06-06 Release date: 2020-09-30 Last modified: 2020-11-25 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling. Nat.Chem.Biol., 16, 2020
6XPA	ScoE with oxovanadium and the CABA substrate bound and His299 and Arg157 flipped out Descriptor: (3~{R})-3-(2-hydroxy-2-oxoethylamino)butanoic acid, ACETATE ION, CHLORIDE ION, ... Authors: Jonnalagadda, R, Drennan, C.L. Deposit date: 2020-07-08 Release date: 2021-01-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Biochemical and crystallographic investigations into isonitrile formation by a nonheme iron-dependent oxidase/decarboxylase. J.Biol.Chem., 296, 2021
7KEK	Structure of the free outer-arm dynein in pre-parallel state Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein alpha heavy chain, ... Authors: Rao, Q, Zhang, K. Deposit date: 2020-10-11 Release date: 2021-09-29 Last modified: 2021-10-20 Method: ELECTRON MICROSCOPY (8 Å) Cite: Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism. Nat.Struct.Mol.Biol., 28, 2021
7QIY	Specific features and methylation sites of a plant ribosome. 40S head ribosomal subunit. Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA head, 40S head ribosomal protein eS19, ... Authors: Cottilli, P, Itoh, Y, Amunts, A. Deposit date: 2021-12-16 Release date: 2022-06-15 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.58 Å) Cite: Cryo-EM structure and rRNA modification sites of a plant ribosome. Plant Commun., 3, 2022
7QPE	Crystal structure of serine hydroxymethyltransferase, isoform 6 from Arabidopsis thaliana (SHM6) Descriptor: NITRATE ION, Serine hydroxymethyltransferase 6 Authors: Ruszkowski, M, Grzechowiak, M, Sekula, B. Deposit date: 2022-01-04 Release date: 2022-08-24 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Arabidopsis thaliana serine hydroxymethyltransferases: functions, structures, and perspectives. Plant Physiol Biochem., 187, 2022
7QX8	Crystal structure of serine hydroxymethyltransferase, isoform 7 from Arabidopsis thaliana (SHM7) Descriptor: Serine hydroxymethyltransferase 7 Authors: Ruszkowski, M, Grzechowiak, M, Sekula, B. Deposit date: 2022-01-26 Release date: 2022-08-24 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.74 Å) Cite: Arabidopsis thaliana serine hydroxymethyltransferases: functions, structures, and perspectives. Plant Physiol Biochem., 187, 2022
6Z6M	Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1 Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... Authors: Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. Deposit date: 2020-05-28 Release date: 2020-07-29 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
7KTR	Cryo-EM structure of the human SAGA coactivator complex (TRRAP, core) Descriptor: Ataxin-7, INOSITOL HEXAKISPHOSPHATE, Isoform 3 of Transcription factor SPT20 homolog, ... Authors: Herbst, D.A, Esbin, M.N, Nogales, E. Deposit date: 2020-11-24 Release date: 2021-11-10 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.93 Å) Cite: Structure of the human SAGA coactivator complex. Nat.Struct.Mol.Biol., 28, 2021
7KTS	Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module) Descriptor: Ataxin-7, Isoform 3 of Transcription factor SPT20 homolog, STAGA complex 65 subunit gamma, ... Authors: Herbst, D.A, Esbin, M.N, Nogales, E. Deposit date: 2020-11-24 Release date: 2021-11-10 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (19.09 Å) Cite: Structure of the human SAGA coactivator complex. Nat.Struct.Mol.Biol., 28, 2021
6YAM	Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA Descriptor: 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ... Authors: Bochler, A, Simonetti, A, Guca, E, Hashem, Y. Deposit date: 2020-03-12 Release date: 2020-04-08 Last modified: 2020-04-22 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
6YEF	70S initiation complex with assigned rRNA modifications from Staphylococcus aureus Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ... Authors: Fatkhullin, B, Golubev, A, Khusainov, I, Yusupova, G, Yusupov, M. Deposit date: 2020-03-24 Release date: 2021-01-27 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Cryo-EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 angstrom resolution. Febs Lett., 594, 2020
5ITC	2.2-Angstrom in meso crystal structure of Haloquadratum Walsbyi Bacteriorhodopsin (HwBR) from Styrene Maleic Acid (SMA) Polymer Nanodiscs Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Bacteriorhodopsin-I, ... Authors: Broecker, J, Eger, B.T, Ernst, O.P. Deposit date: 2016-03-16 Release date: 2017-01-25 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.999 Å) Cite: Crystallogenesis of Membrane Proteins Mediated by Polymer-Bounded Lipid Nanodiscs. Structure, 25, 2017
5IT7	Structure of the Kluyveromyces lactis 80S ribosome in complex with the cricket paralysis virus IRES and eEF2 Descriptor: (2S)-1-amino-N,N,N-trimethyl-1-oxobutan-2-aminium, 18S ribosomal RNA, 25S ribosomal RNA, ... Authors: Murray, J, Savva, C.G, Shin, B.S, Dever, T.E, Ramakrishnan, V, Fernandez, I.S. Deposit date: 2016-03-16 Release date: 2016-05-18 Last modified: 2018-11-21 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural characterization of ribosome recruitment and translocation by type IV IRES. Elife, 5, 2016
7K7L	Structure of a hit for G Protein Coupled Receptor Kinase 2 (GRK2) Inhibitor for the Potential Treatment of Heart Failure Descriptor: 3-benzyl-6-(1H-pyrazol-4-yl)quinazolin-4(3H)-one, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Spurlino, J.C, Milligan, C. Deposit date: 2020-09-23 Release date: 2020-10-28 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.539 Å) Cite: Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitor. Bioorg.Med.Chem.Lett., 30, 2020
6YLH	Rix1-Rea1 pre-60S particle - full composite structure Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Kater, L, Beckmann, R. Deposit date: 2020-04-07 Release date: 2020-07-29 Last modified: 2020-09-02 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis. Mol.Cell, 79, 2020
6Y7N	The crystal structure of the eight-bladed symmetrical designer protein Tako8 in the presence of tellurotungstic Anderson-Evans (TEW) Descriptor: Tako8 Authors: Vandebroek, L, Noguchi, H, Parac-Vogt, T.N, Van Meervelt, L, Voet, A.R.D. Deposit date: 2020-03-02 Release date: 2020-12-16 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Shape and Size Complementarity-Induced Formation of Supramolecular Protein Assemblies with Metal-Oxo Clusters Cryst.Growth Des., 2021
7QGG	Neuronal RNA granules are ribosome complexes stalled at the pre-translocation state Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Pulk, A, Kipper, K, Mansour, A. Deposit date: 2021-12-08 Release date: 2022-10-26 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.86 Å) Cite: Neuronal RNA granules are ribosome complexes stalled at the pre-translocation state. J.Mol.Biol., 434, 2022
6Y7P	The complex between the eight-bladed symmetrical designer protein Tako8 and 1:2 zirconium(IV) Wells-Dawson (ZrWD) Descriptor: Tako8, W-Zr-cluster Authors: Vandebroek, L, Noguchi, H, Parac-Vogt, T.N, Van Meervelt, L, Voet, A.R.D. Deposit date: 2020-03-02 Release date: 2020-12-16 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Shape and Size Complementarity-Induced Formation of Supramolecular Protein Assemblies with Metal-Oxo Clusters Cryst.Growth Des., 2021

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