PDB: 97814 resultsInfo pagesStatus searchChemie searchBIRD

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6GO6	TdT chimera (Loop1 of pol mu) - ternary complex with downstream dsDNA Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*AP*AP*C)-3'), DNA (5'-D(*TP*TP*TP*TP*TP*GP*GP*C)-3'), ... Authors: Loc'h, J, Gerodimos, C.A, Rosario, S, Lieber, M.R, Delarue, M. Deposit date: 2018-06-01 Release date: 2019-06-05 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction. J.Biol.Chem., 294, 2019
7MBK	N-terminal domain of mouse surfactant protein B, 6W mutant Descriptor: Pulmonary surfactant-associated protein B Authors: Milicic, G, Rapoport, T.A. Deposit date: 2021-03-31 Release date: 2021-04-14 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.17 Å) Cite: Mechanism of Lamellar Body Formation by Lung Surfactant Protein B. Mol.Cell, 81, 2021
4X5R	Crystal structure of FimH in complex with a squaryl-phenyl alpha-D-mannopyranoside derivative Descriptor: 2-chloro-4-{[2-(4-methylpiperazin-1-yl)-3,4-dioxocyclobut-1-en-1-yl]amino}phenyl alpha-D-mannopyranoside, Protein FimH, SULFATE ION Authors: Preston, R.C, Jakob, R.P, Fiege, B, Zihlmann, P, Rabbani, S, Schwardt, O, Jiang, X, Ernst, B, Maier, T. Deposit date: 2014-12-05 Release date: 2015-05-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.65 Å) Cite: The Tyrosine Gate of the Bacterial Lectin FimH: A Conformational Analysis by NMR Spectroscopy and X-ray Crystallography. Chembiochem, 16, 2015
6GO5	TdT chimera (Loop1 of pol mu) - Ternary complex with 1-nt gapped DNA substrate Descriptor: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (5'-D(*AP*CP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*GP*GP*CP*AP*AP*AP*CP*A)-3'), ... Authors: Loc'h, J, Gerodimos, C.A, Rosario, S, Lieber, M.R, Delarue, M. Deposit date: 2018-06-01 Release date: 2019-06-05 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction. J.Biol.Chem., 294, 2019
3IAY	Ternary complex of DNA polymerase delta Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', 5'-D(*TP*AP*AP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ... Authors: Swan, M.K, Aggarwal, A.K. Deposit date: 2009-07-15 Release date: 2009-09-22 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta Nat.Struct.Mol.Biol., 16, 2009
2Z6Q	Ternary structure of Arg165Ala M.HhaI C5-Cytosine DNA methyltransferase with unmodified DNA and AdoHcy Descriptor: 2'-DEOXYCYTIDINE, DNA (5'-D(*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3'), DNA (5'-D(*DGP*DCP*DTP*DAP*DTP*DC)-3'), ... Authors: Shieh, F.K. Deposit date: 2007-08-08 Release date: 2007-08-28 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.79 Å) Cite: The role of Arg165 towards base flipping, base stabilization and catalysis in M.HhaI J.Mol.Biol., 362, 2006
2IU1	Crystal structure of eIF5 C-terminal domain Descriptor: EUKARYOTIC TRANSLATION INITIATION FACTOR 5 Authors: Bieniossek, C, Schuetz, P, Baumann, U. Deposit date: 2006-05-26 Release date: 2006-06-01 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The Crystal Structure of the Carboxy-Terminal Domain of Human Translation Initiation Factor Eif5. J.Mol.Biol., 360, 2006
5ME5	Crystal Structure of eiF4E from C. melo bound to a eIF4G peptide Descriptor: Eukaryotic transcription initiation factor 4E, SULFATE ION, eIF4G Authors: Querol-Audi, J, Silva, C, Miras, M, Truniger, V, Aranda-Regules, M, Verdaguer, N. Deposit date: 2016-11-14 Release date: 2017-08-23 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of eIF4E in Complex with an eIF4G Peptide Supports a Universal Bipartite Binding Mode for Protein Translation. Plant Physiol., 174, 2017
4DOC	Ternary complex of dna polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monochlororomethylene triphosphate:binding of S-isomer Descriptor: 5'-O-[(R)-{[(S)-[(S)-chloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-2'-deoxyguanosine, C C G A C C G C G C A T C A G C, CHLORIDE ION, ... Authors: Batra, V.K. Deposit date: 2012-02-09 Release date: 2012-06-13 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.949 Å) Cite: Beta,gamma-CHF- and beta,gamma-CHCl-dGTP Diastereomers: Synthesis, Discrete (31)P NMR Signatures, and Absolute Configurations of New Stereochemical Probes for DNA Polymerases J.Am.Chem.Soc., 134, 2012
4DOB	Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monochlororomethylene triphosphate: Stereoselective binding of R-isomer Descriptor: 5'-O-[(R)-{[(R)-[(R)-chloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-2'-deoxyguanosine, C C G A C C G C G C A T C A G C, CHLORIDE ION, ... Authors: Batra, V.K. Deposit date: 2012-02-09 Release date: 2012-06-13 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Beta,Gamma-CHF- and beta,gamma-CHCl-dGTP Diastereomers: Synthesis, Discrete (31)P NMR Signatures, and Absolute Configurations of New Stereochemical Probes for DNA Polymerases J.Am.Chem.Soc., 134, 2012
6BEM	Ternary complex crystal structure of DNA polymerase Beta with S-isomer of beta-gamma-CHCL-dCTP Descriptor: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 5'-O-[(R)-{[(R)-[(S)-chloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-2'-deoxycytidine, CHLORIDE ION, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2017-10-25 Release date: 2018-10-31 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
4DOA	Ternary complex of dna polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate: non-interactive binding of s-isomer Descriptor: 2'-deoxy-5'-O-[(R)-{[(R)-[(S)-fluoro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]guanosine, C C G A C C G C G C A T C A G C, CHLORIDE ION, ... Authors: Batra, V.K. Deposit date: 2012-02-09 Release date: 2012-06-13 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.051 Å) Cite: Beta,gamma-CHF- and beta,gamma-CHCl-dGTP Diastereomers: Synthesis, Discrete (31)P NMR Signatures, and Absolute Configurations of New Stereochemical Probes for DNA Polymerases J.Am.Chem.Soc., 134, 2012
3PW4	Ternary complex of Aflatoxin B1 Adduct modified DNA (AFB1-N7-Gua) with DNA Polymerase IV and incoming dATP Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 8,9-DIHYDRO-9-HYDROXY-AFLATOXIN B1, CALCIUM ION, ... Authors: Banerjee, S. Deposit date: 2010-12-07 Release date: 2011-08-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Bypass of Aflatoxin B(1) Adducts by the Sulfolobus solfataricus DNA Polymerase IV. J.Am.Chem.Soc., 133, 2011
3PW5	Ternary complex of Aflatoxin B1 Adduct modified DNA (AFB1-N7-Gua) with DNA Polymerase IV and incoming dTTP Descriptor: 8,9-DIHYDRO-9-HYDROXY-AFLATOXIN B1, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'), ... Authors: Banerjee, S. Deposit date: 2010-12-07 Release date: 2011-08-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3 Å) Cite: Bypass of Aflatoxin B(1) Adducts by the Sulfolobus solfataricus DNA Polymerase IV. J.Am.Chem.Soc., 133, 2011
3PVX	Binary complex of Aflatoxin B1 Adduct modified DNA (AFB1-FAPY) with DNA Polymerase IV Descriptor: CALCIUM ION, DNA (5'-D(*AP*TP*TP*(PVX)P*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'), ... Authors: Banerjee, S. Deposit date: 2010-12-07 Release date: 2011-08-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.03 Å) Cite: Bypass of Aflatoxin B(1) Adducts by the Sulfolobus solfataricus DNA Polymerase IV. J.Am.Chem.Soc., 133, 2011
3PW0	Ternary complex of Aflatoxin B1 Adduct modified DNA (AFB1-FAPY) with DNA Polymerase IV and incoming dATP Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'), ... Authors: Banerjee, S. Deposit date: 2010-12-07 Release date: 2011-08-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.91 Å) Cite: Bypass of Aflatoxin B(1) Adducts by the Sulfolobus solfataricus DNA Polymerase IV. J.Am.Chem.Soc., 133, 2011
3PW7	Ternary complex of Aflatoxin B1 Adduct modified DNA (AFB1-N7-Gua) with DNA Polymerase IV and incoming dCTP Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 8,9-DIHYDRO-9-HYDROXY-AFLATOXIN B1, CALCIUM ION, ... Authors: Banerjee, S. Deposit date: 2010-12-07 Release date: 2011-08-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Bypass of Aflatoxin B(1) Adducts by the Sulfolobus solfataricus DNA Polymerase IV. J.Am.Chem.Soc., 133, 2011
6BEL	Ternary complex crystal structure of DNA polymerase Beta with R-isomer of beta-gamma-CHF-dCTP Descriptor: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-deoxy-5'-O-[(R)-{[(R)-[(R)-fluoro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine, CHLORIDE ION, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2017-10-25 Release date: 2018-10-31 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.898 Å) Cite: Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
4DO9	Ternary complex of dna polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate: stereoselective binding of r-isomer Descriptor: 2'-DEOXY-5'-O-[(R)-{[(R)-[(R)-FLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]GUANOSINE, C C G A C C G C G C A T C A G C, CHLORIDE ION, ... Authors: Batra, V.K. Deposit date: 2012-02-09 Release date: 2012-06-13 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Beta,gamma-CHF- and beta,gamma-CHCl-dGTP Diastereomers: Synthesis, Discrete (31)P NMR Signatures, and Absolute Configurations of New Stereochemical Probes for DNA Polymerases J.Am.Chem.Soc., 134, 2012
6CRB	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CF2, beta, gamma dATP analogue Descriptor: 9-{2-deoxy-5-O-[(S)-{[(S)-[difluoro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-alpha-D-erythro-pentofuranosyl}-9H-purin-6-amine, DNA polymerase beta, Downstream Primer Strand, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2018-03-16 Release date: 2018-07-18 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.151 Å) Cite: Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
6CR4	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with dATP Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2018-03-16 Release date: 2018-07-18 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
6CTL	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CHCL-R/S isomers, beta, gamma dTTP analogue Descriptor: 5'-O-[(R)-{[(R)-[(R)-chloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]thymidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2018-03-23 Release date: 2018-06-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2 Å) Cite: Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
3PW2	Ternary complex of Aflatoxin B1 Adduct modified DNA (AFB1-FAPY) with DNA Polymerase IV and incoming dTTP Descriptor: CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'), DNA (5'-D(*TP*TP*(PVX)P*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ... Authors: Banerjee, S. Deposit date: 2010-12-07 Release date: 2011-08-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.74 Å) Cite: Bypass of Aflatoxin B(1) Adducts by the Sulfolobus solfataricus DNA Polymerase IV. J.Am.Chem.Soc., 133, 2011
6CR7	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CHF, beta, gamma dATP analogue Descriptor: 9-{2-deoxy-5-O-[(R)-{[(R)-[(R)-fluoro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-alpha-D-erythro-pentofuranosyl}-9H-purin-6-amine, CHLORIDE ION, DNA polymerase beta, ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2018-03-16 Release date: 2018-07-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
6CR3	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CBr2, beta, gamma dATP analogue Descriptor: 2'-deoxy-5'-O-[(R)-{[(R)-[dibromo(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]adenosine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... Authors: Batra, V.K, Wilson, S.H. Deposit date: 2018-03-16 Release date: 2018-06-27 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018

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