6CRB

Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CF2, beta, gamma dATP analogue

Summary for 6CRB

DescriptorDNA polymerase beta, Template Strand, Primer Strand, ... (8 entities in total)
Functional Keywordsconformational change, enzyme mechanism, lfer, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total molecular weight48301.32
Authors
Batra, V.K.,Wilson, S.H. (deposition date: 2018-03-16, release date: 2018-07-18)
Primary citation
Batra, V.K.,Oertell, K.,Beard, W.A.,Kashemirov, B.A.,McKenna, C.E.,Goodman, M.F.,Wilson, S.H.
Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs.
Biochemistry, 57:3934-3944, 2018
PubMed: 29874056 (PDB entries with the same primary citation)
DOI: 10.1021/acs.biochem.8b00418
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.151 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.275103.1%1.8%20.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution