6GO5
TdT chimera (Loop1 of pol mu) - Ternary complex with 1-nt gapped DNA substrate
Summary for 6GO5
Entry DOI | 10.2210/pdb6go5/pdb |
Descriptor | DNA nucleotidylexotransferase,DNA-directed DNA/RNA polymerase mu,DNA nucleotidylexotransferase, DNA (5'-D(*CP*GP*CP*TP*GP*GP*CP*AP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*TP*G)-3'), ... (8 entities in total) |
Functional Keywords | nhej pathway, dna bridging, dna polymerase polx, dna binding protein |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 8 |
Total formula weight | 107332.65 |
Authors | Loc'h, J.,Gerodimos, C.A.,Rosario, S.,Lieber, M.R.,Delarue, M. (deposition date: 2018-06-01, release date: 2019-06-05, Last modification date: 2024-05-15) |
Primary citation | Loc'h, J.,Gerodimos, C.A.,Rosario, S.,Tekpinar, M.,Lieber, M.R.,Delarue, M. Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction. J.Biol.Chem., 294:10579-10595, 2019 Cited by PubMed: 31138645DOI: 10.1074/jbc.RA119.008739 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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