6CR7

Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CHF, beta, gamma dATP analogue

Summary for 6CR7

Entry DOI	10.2210/pdb6cr7/pdb
Descriptor	Template Strand, Primer Strand, Downstream Primer Strand, ... (9 entities in total)
Functional Keywords	conformational change, enzyme mechanism, lfer, transferase-dna complex, transferase/dna
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	48373.69
Authors	Batra, V.K.,Wilson, S.H. (deposition date: 2018-03-16, release date: 2018-07-04, Last modification date: 2023-10-04)
Primary citation	Batra, V.K.,Oertell, K.,Beard, W.A.,Kashemirov, B.A.,McKenna, C.E.,Goodman, M.F.,Wilson, S.H. Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57:3934-3944, 2018 Cited by PubMed: 29874056 DOI: 10.1021/acs.biochem.8b00418 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation