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1P91
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Crystal Structure of RlmA(I) enzyme: 23S rRNA n1-G745 methyltransferase (NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER19)
Descriptor: Ribosomal RNA large subunit methyltransferase A, S-ADENOSYLMETHIONINE, SULFATE ION, ...
Authors:Das, K, Acton, T, Montelione, G, Arnold, E, Northeast Structural Genomics Consortium (NESG)
Deposit date:2003-05-08
Release date:2004-03-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of RlmAI: implications for understanding the 23S rRNA G745/G748-methylation at the macrolide antibiotic-binding site.
Proc.Natl.Acad.Sci.Usa, 101, 2004
7QZP
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Identification and characterization of an RRM-containing, ELAV-like, RNA binding protein in Acinetobacter Baumannii
Descriptor: Hypothetical RNA binding protein from Acinetobacter baumannii
Authors:Ciani, C, Perez-Rafols, A, Bonomo, I, Micaelli, M, Esposito, A, Zucal, C, Belli, R, D'Agostino, V.G, Bianconi, I, Calderone, V, Cerofolini, L, Fragai, M, Provenzani, A.
Deposit date:2022-01-31
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Identification and Characterization of an RRM-Containing, RNA Binding Protein in Acinetobacter baumannii .
Biomolecules, 12, 2022
7BOH
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BU of 7boh by Molmil
Complete Bacterial 30S ribosomal subunit assembly complex state E (+RbfA)(Consensus Refinement)
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
Deposit date:2021-01-25
Release date:2021-12-08
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
1B2M
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BU of 1b2m by Molmil
THREE-DIMENSIONAL STRUCTURE OF RIBONULCEASE T1 COMPLEXED WITH AN ISOSTERIC PHOSPHONATE ANALOGUE OF GPU: ALTERNATE SUBSTRATE BINDING MODES AND CATALYSIS.
Descriptor: 5'-R(*GP*(U34))-3', RIBONUCLEASE T1
Authors:Arni, R.K, Watanabe, L, Ward, R.J, Kreitman, R.J, Kumar, K, Walz Jr, F.G.
Deposit date:1998-11-27
Release date:1999-03-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of ribonuclease T1 complexed with an isosteric phosphonate substrate analogue of GpU: alternate substrate binding modes and catalysis.
Biochemistry, 38, 1999
6WVJ
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BU of 6wvj by Molmil
Cryo-EM structure of Bacillus subtilis RNA Polymerase elongation complex
Descriptor: DNA (5'-D(*TP*GP*TP*CP*GP*GP*GP*CP*GP*TP*CP*CP*GP*CP*GP*CP*GP*CP*C)-3'), DNA (5'-D(P*AP*CP*GP*CP*CP*CP*GP*AP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Newing, T, Tolun, G, Oakley, A.J.
Deposit date:2020-05-06
Release date:2020-11-18
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Molecular basis for RNA polymerase-dependent transcription complex recycling by the helicase-like motor protein HelD.
Nat Commun, 11, 2020
4KB1
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BU of 4kb1 by Molmil
Crystal structure of RNase T in complex with a bluge DNA (two nucleotide insertion CT )
Descriptor: Bulge DNA, MAGNESIUM ION, Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2013-04-23
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
Plos Biol., 12, 2014
8OMR
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BU of 8omr by Molmil
Human tRNA guanine transglycosylase (TGT) bound to tRNAAsp
Descriptor: 9-DEAZAGUANINE, Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase catalytic subunit 1, ...
Authors:Sievers, K, Neumann, P, Susac, L, Trowitzsch, S, Tampe, R, Ficner, R.
Deposit date:2023-03-31
Release date:2023-12-20
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural and functional insights into tRNA recognition by human tRNA guanine transglycosylase.
Structure, 32, 2024
4WQT
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BU of 4wqt by Molmil
Thermus thermophilus RNA polymerase complexed with an RNA cleavage stimulating factor (a GreA/Gfh1 chimeric protein)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Murayama, Y, Sekine, S, Yokoyama, S.
Deposit date:2014-10-22
Release date:2015-02-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions.
Mol.Cell, 57, 2015
8SY5
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BU of 8sy5 by Molmil
E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dS-BTP base pair in the active site
Descriptor: 2-oxo-2-hydroadenosine 5'-(tetrahydrogen triphosphate), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Shan, Z, Lyumkis, D, Oh, J, Wang, D.
Deposit date:2023-05-24
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase.
Nat Commun, 14, 2023
8SY6
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BU of 8sy6 by Molmil
E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-UTP base pair in the active site
Descriptor: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Shan, Z, Lyumkis, D, Oh, J, Wang, D.
Deposit date:2023-05-24
Release date:2023-12-27
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase.
Nat Commun, 14, 2023
8SY7
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BU of 8sy7 by Molmil
E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-STP base pair in the active site
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Shan, Z, Lyumkis, D, Oh, J, Wang, D.
Deposit date:2023-05-24
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase.
Nat Commun, 14, 2023
6LSE
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BU of 6lse by Molmil
Crystal structure of the enterovirus 71 polymerase elongation complex (C3S6A/C3S6B form)
Descriptor: Genome polyprotein, PYROPHOSPHATE 2-, RNA (35-MER), ...
Authors:Wang, M, Shu, B, Jing, X, Gong, P.
Deposit date:2020-01-17
Release date:2020-04-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
Nat Commun, 11, 2020
4WYW
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BU of 4wyw by Molmil
Mutant K20E of 3D polymerase from Foot-and-Mouth Disease Virus
Descriptor: ACETATE ION, GLYCEROL, RNA-directed RNA polymerase 3D-POL, ...
Authors:Ferrer-Orta, C, Verdaguer, N, de la Higuera, I, Domingo, E.
Deposit date:2014-11-18
Release date:2015-05-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
6S2L
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BU of 6s2l by Molmil
FMDV 3D polymerase crystallized in presence of (F)uridylylated VPg peptide
Descriptor: GLYCEROL, Genome polyprotein
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2019-06-21
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:(F)uridylylated Peptides Linked to VPg1 of Foot-and- Mouth Disease Virus (FMDV): Design, Synthesis and X-Ray Crystallography of the Complexes with FMDV RNA-Dependent RNA Polymerase.
Molecules, 24, 2019
2J0Q
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BU of 2j0q by Molmil
The crystal structure of the Exon Junction Complex at 3.2 A resolution
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ...
Authors:Bono, F, Ebert, J, Lorentzen, E, Conti, E.
Deposit date:2006-08-04
Release date:2006-08-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Crystal Structure of the Exon Junction Complex Reveals How It Maintains a Stable Grip on Mrna.
Cell(Cambridge,Mass.), 126, 2006
6LSH
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BU of 6lsh by Molmil
Crystal structure of the enterovirus 71 polymerase elongation complex (C2S6M form)
Descriptor: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ...
Authors:Li, R, Wang, M, Jing, X, Gong, P.
Deposit date:2020-01-17
Release date:2020-04-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.231 Å)
Cite:Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
Nat Commun, 11, 2020
6LSG
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BU of 6lsg by Molmil
Crystal structure of the enterovirus 71 polymerase elongation complex (C0S6M form)
Descriptor: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ...
Authors:Li, R, Wang, M, Jing, X, Gong, P.
Deposit date:2020-01-17
Release date:2020-04-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
Nat Commun, 11, 2020
6EVJ
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BU of 6evj by Molmil
Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter and capped RNA primer
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(GDM))-R(P*AP*AP*U)-3'), ...
Authors:Pflug, A, Cusack, S.
Deposit date:2017-11-01
Release date:2017-12-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
Nucleic Acids Res., 46, 2018
6P70
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BU of 6p70 by Molmil
X-ray crystal structure of bacterial RNA polymerase and pyrBI promoter complex
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*CP*GP*AP*TP*CP*TP*TP*TP*GP*CP*CP*GP*GP*G)-3'), DNA (5'-D(P*TP*CP*CP*CP*GP*GP*CP*AP*AP*AP*TP*TP*GP*TP*CP*CP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-06-04
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.052 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
3QO3
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BU of 3qo3 by Molmil
Crystal structure of Escherichia coli Hfq, in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Protein hfq
Authors:Beich-Frandsen, M, Vecerek, B, Hammele, H, Kloiber, K, Sjoeblom, B, Blasi, U, Djinovic-Carugo, K.
Deposit date:2011-02-09
Release date:2012-02-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and biochemical studies on ATP binding and hydrolysis by the Escherichia coli RNA chaperone Hfq
Plos One, 7, 2012
4KAZ
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BU of 4kaz by Molmil
Crystal structure of RNase T in complex with a Y structured DNA
Descriptor: DNA (5'-D(*TP*TP*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*CP*C)-3'), MAGNESIUM ION, Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2013-04-23
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
Plos Biol., 12, 2014
8S95
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BU of 8s95 by Molmil
Crystal Structure of Poliovirus (type 1 Mahoney) cloverleaf RNA with tRNA scaffold
Descriptor: Lysine tRNA scaffold,Poliovirus cloverleaf RNA
Authors:McNeme, S.C, Choi, K.H.
Deposit date:2023-03-27
Release date:2023-08-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for cloverleaf RNA-initiated viral genome replication.
Nucleic Acids Res., 51, 2023
1CSJ
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BU of 1csj by Molmil
CRYSTAL STRUCTURE OF THE RNA-DEPENDENT RNA POLYMERASE OF HEPATITIS C VIRUS
Descriptor: HEPATITIS C VIRUS RNA POLYMERASE (NS5B)
Authors:Bressanelli, S, Tomei, L, Roussel, A, Incitti, I, Vitale, R.L, Mathieu, M, De Francesco, R, Rey, F.A.
Deposit date:1999-08-18
Release date:1999-11-08
Last modified:2013-02-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus.
Proc.Natl.Acad.Sci.USA, 96, 1999
5V7C
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BU of 5v7c by Molmil
Crystal structure of LARP1-unique domain DM15 bound 5'TOP RNA sequence
Descriptor: La-related protein 1, RNA (5'-R(*CP*UP*UP*UP*UP*CP*CP*G)-3')
Authors:Berman, A.J, Lahr, R.M, Al-Ashtal, H.A.
Deposit date:2017-03-20
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs.
Elife, 6, 2017
3UMY
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BU of 3umy by Molmil
Crystal structure of mutant ribosomal protein T217A TthL1 in complex with 80nt 23S RNA from Thermus thermophilus
Descriptor: 50S ribosomal protein L1, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Gabdulkhakov, A.G, Nevskaya, N.A, Nikonov, S.V.
Deposit date:2011-11-15
Release date:2012-10-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of mutant ribosomal protein T217A TthL1 in complex with 80nt 23S RNA from Thermus thermophilus
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