5V7C
Crystal structure of LARP1-unique domain DM15 bound 5'TOP RNA sequence
Summary for 5V7C
Entry DOI | 10.2210/pdb5v7c/pdb |
Related | 4ZC4 5V4R 5v87 |
Descriptor | La-related protein 1, RNA (5'-R(*CP*UP*UP*UP*UP*CP*CP*G)-3') (3 entities in total) |
Functional Keywords | cap-binding, rna-binding, dm15, 5'top, rna binding protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm : Q6PKG0 |
Total number of polymer chains | 2 |
Total formula weight | 22056.74 |
Authors | Berman, A.J.,Lahr, R.M.,Al-Ashtal, H.A. (deposition date: 2017-03-20, release date: 2017-04-19, Last modification date: 2023-10-04) |
Primary citation | Lahr, R.M.,Fonseca, B.D.,Ciotti, G.E.,Al-Ashtal, H.A.,Jia, J.J.,Niklaus, M.R.,Blagden, S.P.,Alain, T.,Berman, A.J. La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs. Elife, 6:-, 2017 Cited by PubMed: 28379136DOI: 10.7554/eLife.24146 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.59 Å) |
Structure validation
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