8AK6
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8AF3
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![BU of 8af3 by Molmil](/molmil-images/mine/8af3) | Sterol carrier protein Artifical metalloenzyme incorporating Q111C mutation coupled to 2,2'-bipyridine | Descriptor: | COPPER (II) ION, Enoyl-CoA hydratase 2, FRAGMENT OF TRITON X-100, ... | Authors: | Richardson, J.M, Klemencic, E, Jarvis, A.G. | Deposit date: | 2022-07-15 | Release date: | 2023-08-16 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Using BpyAla to generate copper artificial metalloenzymes: a catalytic and structural study. Catalysis Science And Technology, 14, 2024
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4DPO
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![BU of 4dpo by Molmil](/molmil-images/mine/4dpo) | Crystal structure of a conserved protein MM_1583 from Methanosarcina mazei Go1 | Descriptor: | Conserved protein | Authors: | Agarwal, R, Chamala, S, Evans, R, Gizzi, A, Hillerich, B, Kar, A, LaFleur, J, Foti, R, Siedel, R, Zencheck, W, Villigas, G, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-02-13 | Release date: | 2012-02-29 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Crystal structure of a conserved protein MM_1583 from Methanosarcina mazei Go1 To be Published
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4DQX
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![BU of 4dqx by Molmil](/molmil-images/mine/4dqx) | Crystal structure of a short chain dehydrogenase from Rhizobium etli CFN 42 | Descriptor: | Probable oxidoreductase protein | Authors: | Agarwal, R, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, LaFleur, J, Siedel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-02-16 | Release date: | 2012-02-29 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a short chain dehydrogenase from Rhizobium etli CFN 42 To be Published
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8BQN
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4J3C
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![BU of 4j3c by Molmil](/molmil-images/mine/4j3c) | Crystal structure of 16S ribosomal RNA methyltransferase RsmE | Descriptor: | Ribosomal RNA small subunit methyltransferase E | Authors: | Eswaramoorthy, S, Chamala, S, Evans, B, Foti, F, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Al Obaidi, N, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-02-05 | Release date: | 2013-02-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of 16S ribosomal RNA methyltransferase RsmE TO BE PUBLISHED
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4JFC
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![BU of 4jfc by Molmil](/molmil-images/mine/4jfc) | Crystal structure of a enoyl-CoA hydratase from Polaromonas sp. JS666 | Descriptor: | Enoyl-CoA hydratase, GLYCEROL | Authors: | Kumaran, D, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Al Obaidi, N, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-02-28 | Release date: | 2013-05-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal structure of a enoyl-CoA hydratase from Polaromonas sp. JS666 To be Published
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4JCU
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![BU of 4jcu by Molmil](/molmil-images/mine/4jcu) | Crystal structure of a 5-carboxymethyl-2-hydroxymuconate isomerase from Deinococcus radiodurans R1 | Descriptor: | 5-carboxymethyl-2-hydroxymuconate isomerase | Authors: | Kumaran, D, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Al Obaidi, N, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-02-22 | Release date: | 2013-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of a 5-carboxymethyl-2-hydroxymuconate isomerase from Deinococcus radiodurans R1 To be Published
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4E8G
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![BU of 4e8g by Molmil](/molmil-images/mine/4e8g) | Crystal structure of an enolase (mandelate racemase subgroup) from paracococus denitrificans pd1222 (target nysgrc-012907) with bound mg | Descriptor: | MAGNESIUM ION, Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein, ... | Authors: | Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Sojitra, S, Chamala, S, Kar, A, Lafleur, J, Villigas, G, Evans, B, Hammonds, J, Gizzi, A, Zencheck, W.D, Hillerich, B, Love, J, Seidel, R.D, Bonanno, J.B, Gerlt, J.A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-03-20 | Release date: | 2012-05-02 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine. MBio, 5, 2014
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4JJ9
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![BU of 4jj9 by Molmil](/molmil-images/mine/4jj9) | Crystal Structure of 5-carboxymethyl-2-hydroxymuconate delta-isomerase | Descriptor: | 5-carboxymethyl-2-hydroxymuconate delta-isomerase, SULFATE ION | Authors: | Eswaramoorthy, S, Chamala, S, Evans, B, Foti, F, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Al Obaidi, N, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-03-07 | Release date: | 2013-05-01 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal Structure of 5-carboxymethyl-2-hydroxymuconate delta-isomerase To be Published
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4F3S
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![BU of 4f3s by Molmil](/molmil-images/mine/4f3s) | Crystal structure of periplasmic D-alanine ABC transporter from Salmonella enterica | Descriptor: | D-ALANINE, GLYCINE, PHOSPHATE ION, ... | Authors: | Agarwal, R, Chamala, S, Evans, B, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Siedel, R, Villigas, G, Zencheck, W, Foti, R, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-05-09 | Release date: | 2012-05-23 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Crystal structure of periplasmic D-alanine ABC transporter from Salmonella enterica To be Published
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6O9K
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![BU of 6o9k by Molmil](/molmil-images/mine/6o9k) | 70S initiation complex | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Frank, J, Gonzalez Jr, R.L, kaledhonkar, S, Fu, Z, Caban, K, Li, W, Chen, B, Sun, M. | Deposit date: | 2019-03-14 | Release date: | 2019-05-29 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Late steps in bacterial translation initiation visualized using time-resolved cryo-EM. Nature, 570, 2019
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6O9J
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![BU of 6o9j by Molmil](/molmil-images/mine/6o9j) | 70S Elongation Competent Ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Frank, J, Gonzalez Jr, R.L, Kaledhonkar, S, Fu, Z, Caban, K, Li, W, Chen, B, Sun, M. | Deposit date: | 2019-03-14 | Release date: | 2019-05-29 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Late steps in bacterial translation initiation visualized using time-resolved cryo-EM. Nature, 570, 2019
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6ORL
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![BU of 6orl by Molmil](/molmil-images/mine/6orl) | RF1 pre-accommodated 70S complex at 24 ms | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | Deposit date: | 2019-04-30 | Release date: | 2019-06-19 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
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6OT3
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![BU of 6ot3 by Molmil](/molmil-images/mine/6ot3) | RF2 accommodated state bound Release complex 70S at 24 ms | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | Deposit date: | 2019-05-02 | Release date: | 2019-06-19 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
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6OST
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![BU of 6ost by Molmil](/molmil-images/mine/6ost) | RF2 pre-accommodated state bound Release complex 70S at 24ms | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | Deposit date: | 2019-05-02 | Release date: | 2019-06-19 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
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6OGG
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![BU of 6ogg by Molmil](/molmil-images/mine/6ogg) | 70S termination complex with RF2 bound to the UGA codon. Rotated ribosome with RF2 bound (Structure IV). | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. | Deposit date: | 2019-04-02 | Release date: | 2019-09-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
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6OSK
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![BU of 6osk by Molmil](/molmil-images/mine/6osk) | RF1 accommodated 70S complex at 60 ms | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | Deposit date: | 2019-05-01 | Release date: | 2019-06-26 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
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6ORE
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![BU of 6ore by Molmil](/molmil-images/mine/6ore) | Release complex 70S | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Fu, Z. | Deposit date: | 2019-04-30 | Release date: | 2019-06-19 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
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6OGF
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![BU of 6ogf by Molmil](/molmil-images/mine/6ogf) | 70S termination complex with RF2 bound to the UGA codon. Partially rotated ribosome with RF2 bound (Structure III). | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. | Deposit date: | 2019-04-02 | Release date: | 2019-09-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
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6OSQ
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![BU of 6osq by Molmil](/molmil-images/mine/6osq) | RF1 accommodated state bound Release complex 70S at long incubation time point | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | Deposit date: | 2019-05-02 | Release date: | 2019-06-26 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
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6OGI
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![BU of 6ogi by Molmil](/molmil-images/mine/6ogi) | 70S termination complex with RF2 bound to the UAG codon. Rotated ribosome conformation (Structure V) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. | Deposit date: | 2019-04-02 | Release date: | 2019-09-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
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6OUO
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![BU of 6ouo by Molmil](/molmil-images/mine/6ouo) | RF2 accommodated state bound 70S complex at long incubation time | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | Deposit date: | 2019-05-05 | Release date: | 2019-06-19 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
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6OM6
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![BU of 6om6 by Molmil](/molmil-images/mine/6om6) | Structure of trans-translation inhibitor bound to E. coli 70S ribosome with P site tRNA | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Hoffer, E.D, Mehrani, A, Keiler, K.C, Stagg, S.M, Dunham, C.M. | Deposit date: | 2019-04-18 | Release date: | 2021-02-10 | Last modified: | 2021-09-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo. Nat Commun, 12, 2021
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2C3I
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![BU of 2c3i by Molmil](/molmil-images/mine/2c3i) | CRYSTAL STRUCTURE OF HUMAN PIM1 IN COMPLEX WITH IMIDAZOPYRIDAZIN I | Descriptor: | 1-(3-{6-[(CYCLOPROPYLMETHYL)AMINO]IMIDAZO[1,2-B]PYRIDAZIN-3-YL}PHENYL)ETHANONE, PIMTIDE, PROTO-ONCOGENE SERINE THREONINE PROTEIN KINASE PIM1 | Authors: | Philippakopoulos, P, Knapp, S, Debreczeni, J, Bullock, A, von Delft, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Guo, K, Weigelt, J. | Deposit date: | 2005-10-07 | Release date: | 2005-11-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Analysis Identifies Imidazo[1,2- B]Pyridazines as Pim Kinase Inhibitors with in Vitro Antileukemic Activity. Cancer Res., 67, 2007
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