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8Q43
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BU of 8q43 by Molmil
Crystal structure of cA4-bound Can2 (E341A) in complex with oligo-C DNA
Descriptor: Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*CP*CP*CP*CP*C)-3'), DUF1887 family protein, ...
Authors:Jungfer, K, Sigg, A, Jinek, M.
Deposit date:2023-08-04
Release date:2023-11-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2.
Nucleic Acids Res., 52, 2024
8Q3G
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BU of 8q3g by Molmil
Crystal structure of YTHDC1 in complex with Compound 23 (ZA_385)
Descriptor: 3-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]-~{N}-methyl-benzamide, SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-04
Release date:2023-12-06
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Crystal structure of YTHDC1 in complex with Compound 23 (ZA_385)
To Be Published
8Q3K
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BU of 8q3k by Molmil
The open state of the ASFV apo-RNA polymerase
Descriptor: DNA-directed RNA polymerase RPB1 homolog, DNA-directed RNA polymerase RPB10 homolog, DNA-directed RNA polymerase RPB2 homolog, ...
Authors:Pilotto, S, Sykora, M, Cackett, G, Werner, F.
Deposit date:2023-08-04
Release date:2024-02-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Structure of the recombinant RNA polymerase from African Swine Fever Virus.
Nat Commun, 15, 2024
8KB5
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BU of 8kb5 by Molmil
Cryo-EM structure of the human nucleosome containing H3.8
Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Hirai, H, Kujirai, T, Takizawa, Y, Kurumizaka, H.
Deposit date:2023-08-03
Release date:2023-10-18
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.26133 Å)
Cite:Cryo-EM and biochemical analyses of the nucleosome containing the human histone H3 variant H3.8.
J.Biochem., 174, 2023
8TOF
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BU of 8tof by Molmil
Rpd3S bound to an H3K36Cme3 modified nucleosome
Descriptor: Chromatin modification-related protein EAF3, DNA (176-MER), Histone H2A, ...
Authors:Markert, J.W, Vos, S.M, Farnung, L.
Deposit date:2023-08-03
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of the complete Saccharomyces cerevisiae Rpd3S-nucleosome complex.
Nat Commun, 14, 2023
8KAK
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BU of 8kak by Molmil
Crystal structure of SpyCas9 in complex with sgRNA and 18nt target DNA
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (26-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
Authors:Chen, Y, Chen, J, Liu, L.
Deposit date:2023-08-03
Release date:2024-06-05
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAL
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BU of 8kal by Molmil
Crystal structure of SpyCas9 in complex with sgRNA and 17nt target DNA
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (25-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
Authors:Chen, Y, Chen, J, Liu, L.
Deposit date:2023-08-03
Release date:2024-06-05
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8TOB
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BU of 8tob by Molmil
Acinetobacter GP16 Type IV pilus
Descriptor: Fimbrial protein
Authors:Meng, R, Xing, Z, Zhang, J.
Deposit date:2023-08-03
Release date:2024-03-06
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Structural basis of Acinetobacter type IV pili targeting by an RNA virus.
Nat Commun, 15, 2024
8KAJ
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BU of 8kaj by Molmil
Crystal structure of SpyCas9-crRNA-tracrRNA complex bound to 16nt target DNA
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*CP*AP*AP*TP*AP*CP*CP*TP*TP*TP*TP*AP*TP*CP*CP*AP*TP*AP*AP*AP*TP*TP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
Authors:Chen, Y, Chen, J, Liu, L.
Deposit date:2023-08-03
Release date:2024-06-05
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAM
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BU of 8kam by Molmil
Crystal structure of SpyCas9 in complex with sgRNA and 16nt target DNA
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*CP*AP*AP*TP*AP*CP*CP*TP*CP*TP*TP*CP*AP*AP*TP*TP*AP*GP*AP*AP*CP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
Authors:Chen, Y, Chen, J, Liu, L.
Deposit date:2023-08-03
Release date:2024-06-05
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (3.91 Å)
Cite:Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8TOC
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BU of 8toc by Molmil
Acinetobacter phage AP205
Descriptor: Coat protein, Maturation protein, RNA (4269-MER)
Authors:Meng, R, Xing, Z, Chang, J, Zhang, J.
Deposit date:2023-08-03
Release date:2024-03-06
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Structural basis of Acinetobacter type IV pili targeting by an RNA virus.
Nat Commun, 15, 2024
8KAG
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BU of 8kag by Molmil
Crystal structure of SpyCas9 in complex with sgRNA and target RNA
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, RNA (5'-R(*CP*CP*AP*CP*UP*UP*CP*AP*AP*UP*UP*AP*GP*AP*AP*CP*AP*CP*GP*GP*AP*CP*C)-3'), RNA (98-MER)
Authors:Chen, Y, Chen, J, Liu, L.
Deposit date:2023-08-03
Release date:2024-06-05
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (3.88 Å)
Cite:Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAI
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BU of 8kai by Molmil
Crystal structure of SpyCas9-crRNA-tracrRNA complex bound to 17nt target DNA
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (25-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
Authors:Chen, Y, Chen, J, Liu, L.
Deposit date:2023-08-03
Release date:2024-06-05
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8KAH
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BU of 8kah by Molmil
Crystal structure of SpyCas9-crRNA-tracrRNA complex bound to 18nt target DNA
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (26-MER), DNA (5'-D(*TP*TP*TP*AP*GP*GP*TP*AP*TP*TP*G)-3'), ...
Authors:Chen, Y, Chen, J, Liu, L.
Deposit date:2023-08-03
Release date:2024-06-05
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (3.36 Å)
Cite:Trans-nuclease activity of Cas9 activated by DNA or RNA target binding.
Nat.Biotechnol., 2024
8Q2X
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BU of 8q2x by Molmil
Crystal structure of YTHDC1 in complex with Compound 10 (ZA_294)
Descriptor: 3-[2-chloranyl-6-(methylamino)purin-9-yl]benzoic acid, SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of YTHDC1 in complex with Compound 10 (ZA_294)
To Be Published
8Q2Q
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BU of 8q2q by Molmil
Crystal structure of YTHDC1 in complex with Compound 2b (YL_32)
Descriptor: 2-chloranyl-~{N},9-dimethyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R.K, Li, Y, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of YTHDC1 in complex with Compound 2b (YL_32)
To Be Published
8Q32
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BU of 8q32 by Molmil
Crystal structure of YTHDC1 in complex with Compound 13 (ZA_364)
Descriptor: SULFATE ION, YTH domain-containing protein 1, ~{N}-[2-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]phenyl]methanesulfonamide
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Crystal structure of YTHDC1 in complex with Compound 13 (ZA_364)
To Be Published
8Q31
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BU of 8q31 by Molmil
Crystal structure of YTHDC1 in complex with Compound 12 (ZA_341)
Descriptor: 9-[(2-aminophenyl)methyl]-2-chloranyl-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Crystal structure of YTHDC1 in complex with Compound 12 (ZA_341)
To Be Published
8Q2S
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BU of 8q2s by Molmil
Crystal structure of YTHDC1 in complex with Compound 4 (ZA_232)
Descriptor: 2-chloranyl-~{N}-methyl-9-phenyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Crystal structure of YTHDC1 in complex with Compound 4 (ZA_232)
To Be Published
8Q2T
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BU of 8q2t by Molmil
Crystal structure of YTHDC1 in complex with Compound 5 (ZA_236)
Descriptor: 2-chloranyl-~{N}-methyl-9-(phenylmethyl)purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Crystal structure of YTHDC1 in complex with Compound 5 (ZA_236)
To Be Published
8Q2W
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BU of 8q2w by Molmil
Crystal structure of YTHDC1 in complex with Compound 8 (CS_01)
Descriptor: 2-chloranyl-9-(cyclohexylmethyl)-~{N}-methyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Crystal structure of YTHDC1 in complex with Compound 8 (CS_01)
To Be Published
8Q38
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BU of 8q38 by Molmil
Crystal structure of YTHDC1 in complex with Compound 19 (ZA_347)
Descriptor: SULFATE ION, YTH domain-containing protein 1, methyl 3-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]benzoate
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Crystal structure of YTHDC1 in complex with Compound 19 (ZA_347)
To Be Published
8Q2U
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BU of 8q2u by Molmil
Crystal structure of YTHDC1 in complex with Compound 6 (ZA_308)
Descriptor: 2-chloranyl-~{N}-methyl-9-(pyridin-4-ylmethyl)purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Crystal structure of YTHDC1 in complex with Compound 6 (ZA_308)
To Be Published
8Q2V
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BU of 8q2v by Molmil
Crystal structure of YTHDC1 in complex with Compound 7 (ZA_560)
Descriptor: 2-chloranyl-~{N}-methyl-9-[(2~{S})-oxan-2-yl]purin-6-amine, SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Crystal structure of YTHDC1 in complex with Compound 7 (ZA_560)
To Be Published
8Q2Y
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BU of 8q2y by Molmil
Crystal structure of YTHDC1 in complex with Compound 11 (ZA_572)
Descriptor: 2-[2-chloranyl-6-(methylamino)purin-9-yl]-~{N}-phenyl-ethanamide, SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R.K, Zalesak, F, Caflisch, A.
Deposit date:2023-08-03
Release date:2023-12-06
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Crystal structure of YTHDC1 in complex with Compound 11 (ZA_572)
To Be Published

221051

PDB entries from 2024-06-12

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