8RBU

Crystal structure of HLA-A*11:01 in complex with SVLNDILARL, an 10-mer epitope from SARS-CoV-2 Spike (S975-984)

Summary for 8RBU

Entry DOI	10.2210/pdb8rbu/pdb
Descriptor	HLA class I histocompatibility antigen, Beta-2-microglobulin, Spike protein S2', ... (9 entities in total)
Functional Keywords	human leukocyte antigen, major histocompatibility complex, hla-a11, hla-a*11:01, sars-cov-2, spike, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	54891.08
Authors	Ahn, Y.M.,Maddumage, J.C.,Szeto, C.,Gras, S. (deposition date: 2023-12-05, release date: 2024-05-15, Last modification date: 2024-05-22)
Primary citation	Ahn, Y.M.,Maddumage, J.C.,Grant, E.J.,Chatzileontiadou, D.S.M.,Perera, W.W.J.G.,Baker, B.M.,Szeto, C.,Gras, S. The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific. Curr Res Struct Biol, 7:100148-100148, 2024 Cited by PubMed: 38742159 DOI: 10.1016/j.crstbi.2024.100148 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation