8RCO

Structure of Human Serum Albumin in complex with Aristolochic Acid II at 1.9 A resolution

Replaces:  7OV5

Summary for 8RCO

• Entry DOI: 10.2210/pdb8rco/pdb
• Related: 8RCP
• Descriptor: Serum albumin, MYRISTIC ACID, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: albumin, aristolochic acid, hsa, lipid binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 143173.10

Authors

Pomyalov, S.,Sidorenko, V.S.,Grollman, A.P.,Shoham, G. (deposition date: 2023-12-06, release date: 2024-06-26, Last modification date: 2024-07-03)

• Primary citation: Pomyalov, S.,Minetti, C.A.,Remeta, D.P.,Bonala, R.,Johnson, F.,Zaitseva, I.,Iden, C.,Golebiewska, U.,Breslauer, K.J.,Shoham, G.,Sidorenko, V.S.,Grollman, A.P.; Structural and mechanistic insights into the transport of aristolochic acids and their active metabolites by human serum albumin.; J.Biol.Chem., 300:107358-107358, 2024; PubMed: 38782206; DOI: 10.1016/j.jbc.2024.107358

Experimental method

X-RAY DIFFRACTION (1.9 Å)