PDB: 658 resultsInfo pagesStatus searchChemie searchBIRD

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8G61	mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... Authors: Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. Deposit date: 2023-02-14 Release date: 2023-04-19 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.94 Å) Cite: mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
7QZ6	Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5-fluoroTrp Descriptor: DAUNOMYCIN, Transcriptional regulator, PadR-like family Authors: Thunnissen, A.M.W.H. Deposit date: 2022-01-30 Release date: 2022-11-23 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.15 Å) Cite: The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
7QZ8	Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp Descriptor: DAUNOMYCIN, Transcriptional regulator, PadR-like family Authors: Thunnissen, A.M.W.H. Deposit date: 2022-01-30 Release date: 2022-11-23 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
7QZ7	Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5,6,7-trifluoroTrp Descriptor: DAUNOMYCIN, Transcriptional regulator, PadR-like family Authors: Thunnissen, A.M.W.H. Deposit date: 2022-01-30 Release date: 2022-11-23 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
7QZ9	Transcriptional regulator LmrR with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp Descriptor: Transcriptional regulator, PadR-like family Authors: Thunnissen, A.M.W.H. Deposit date: 2022-01-30 Release date: 2022-11-23 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.31 Å) Cite: The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
7QZ5	Transcriptional regulator LmrR with Trp-67 and Trp-96 replaced by the unnatural amino acid 5-fluoroTrp Descriptor: Transcriptional regulator, PadR-like family Authors: Thunnissen, A.M.W.H. Deposit date: 2022-01-30 Release date: 2022-11-23 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
6OLI	Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-16 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OLE	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-16 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OM7	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-18 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OM0	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-17 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OLF	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-16 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
7R4X	Cryo-EM reconstruction of the human 40S ribosomal subunit - Full map Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Pellegrino, S, Dent, K.C, Spikes, T, Warren, A.J. Deposit date: 2022-02-09 Release date: 2023-02-22 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.15 Å) Cite: Cryo-EM reconstruction of the human 40S ribosomal subunit at 2.15 angstrom resolution. Nucleic Acids Res., 51, 2023
6OLZ	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-17 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
8GLP	mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure) Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... Authors: Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C. Deposit date: 2023-03-22 Release date: 2023-04-19 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (1.67 Å) Cite: mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8G5Z	mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... Authors: Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. Deposit date: 2023-02-14 Release date: 2023-04-19 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.64 Å) Cite: mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8G6J	mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2) Descriptor: (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-heptone, (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 1,4-DIAMINOBUTANE, ... Authors: Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. Deposit date: 2023-02-15 Release date: 2023-04-19 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8G5Y	mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... Authors: Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. Deposit date: 2023-02-14 Release date: 2023-04-19 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.29 Å) Cite: mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8G60	mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... Authors: Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. Deposit date: 2023-02-14 Release date: 2023-04-19 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.54 Å) Cite: mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
6OLG	Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-16 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
7QP7	Structure of the human 48S initiation complex in closed state (h48S AUG closed) Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. Deposit date: 2022-01-03 Release date: 2022-05-11 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
7QP6	Structure of the human 48S initiation complex in open state (h48S AUG open) Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. Deposit date: 2022-01-03 Release date: 2022-05-11 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
6G5I	Cryo-EM structure of a late human pre-40S ribosomal subunit - State R Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. Deposit date: 2018-03-29 Release date: 2018-06-06 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
6G18	Cryo-EM structure of a late human pre-40S ribosomal subunit - State C Descriptor: 40S ribosomal protein S11, 40S ribosomal protein S12, 40S ribosomal protein S13, ... Authors: Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. Deposit date: 2018-03-20 Release date: 2018-06-06 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
6G5H	Cryo-EM structure of a late human pre-40S ribosomal subunit - Mature Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. Deposit date: 2018-03-29 Release date: 2018-06-06 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
6G51	Cryo-EM structure of a late human pre-40S ribosomal subunit - State D Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. Deposit date: 2018-03-28 Release date: 2018-06-06 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018

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