4FF3
| N4 mini-vRNAP transcription initiation complex, 3 min after soaking GTP, ATP and Mn | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Bacteriophage N4 P2 promoter, GUANOSINE-5'-MONOPHOSPHATE, ... | Authors: | Murakami, K.S, Basu, R.S. | Deposit date: | 2012-05-30 | Release date: | 2012-12-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Watching the Bacteriophage N4 RNA Polymerase Transcription by Time-dependent Soak-trigger-freeze X-ray Crystallography. J.Biol.Chem., 288, 2013
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2BF0
| crystal structure of the rpr of pcf11 | Descriptor: | CALCIUM ION, PCF11 | Authors: | Noble, C.G, Hollingworth, D, Martin, S.R, Adeniran, V.E, Smerdon, S.J, Kelly, G, Taylor, I.A, Ramos, A. | Deposit date: | 2004-12-02 | Release date: | 2005-01-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Key Features of the Interaction between Pcf11 Cid and RNA Polymerase II Ctd. Nat.Struct.Mol.Biol., 12, 2005
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4FF4
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2O5J
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2PPB
| Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the ntp substrate analog and antibiotic streptolydigin | Descriptor: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3'), ... | Authors: | Vassylyev, D.G, Vassylyeva, M.N, Artsimovitch, I, Landick, R. | Deposit date: | 2007-04-28 | Release date: | 2007-07-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for substrate loading in bacterial RNA polymerase. Nature, 448, 2007
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3P8B
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7JV7
| Crystal Structure of the yeast RNA Pol II CTD kinase CTDK-1 complex | Descriptor: | CITRATE ANION, CTD kinase subunit alpha, CTD kinase subunit beta, ... | Authors: | Xie, Y, Ren, Y. | Deposit date: | 2020-08-20 | Release date: | 2021-01-27 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.850553 Å) | Cite: | Structure and activation mechanism of the yeast RNA Pol II CTD kinase CTDK-1 complex. Proc.Natl.Acad.Sci.USA, 118, 2021
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2O5I
| Crystal structure of the T. thermophilus RNA polymerase elongation complex | Descriptor: | 5'-D(*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*AP*GP*GP*G)-3', 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP*CP*GP*CP*CP*G)-3', 5'-R(P*GP*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP*G)-3', ... | Authors: | Vassylyev, D.G, Tahirov, T.H, Vassylyeva, M.N. | Deposit date: | 2006-12-06 | Release date: | 2007-07-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for transcription elongation by bacterial RNA polymerase. Nature, 448, 2007
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2CKZ
| X-ray structure of RNA polymerase III subcomplex C17-C25. | Descriptor: | DNA-DIRECTED RNA POLYMERASE III 18 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE III 25 KD POLYPEPTIDE | Authors: | Jasiak, A.J, Armache, K.-J, Martens, B, Jansen, R.-P, Cramer, P. | Deposit date: | 2006-04-24 | Release date: | 2006-07-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural Biology of RNA Polymerase III: Subcomplex C17/-C25 X-Ray Structure and 11-Subunit Enzyme Model Mol.Cell, 23, 2006
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2WHO
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1S0V
| Structural basis for substrate selection by T7 RNA polymerase | Descriptor: | 5'-D(*G*GP*GP*AP*AP*TP*CP*GP*AP*TP*AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*C)-3', 5'-R(*AP*AP*CP*U*GP*CP*GP*GP*CP*GP*AP*U)-3', ... | Authors: | Temiakov, D, Patlan, V, Anikin, M, McAllister, W.T, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-01-05 | Release date: | 2004-02-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for substrate selection by t7 RNA polymerase. Cell(Cambridge,Mass.), 116, 2004
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1YV2
| Hepatitis C virus NS5B RNA-dependent RNA Polymerase genotype 2a | Descriptor: | GLYCEROL, RNA dependent RNA polymerase, SULFATE ION | Authors: | Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. | Deposit date: | 2005-02-14 | Release date: | 2005-03-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structures of the RNA-dependent RNA Polymerase Genotype 2a of Hepatitis C Virus Reveal Two Conformations and Suggest Mechanisms of Inhibition by Non-nucleoside Inhibitors J.Biol.Chem., 280, 2005
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7VW5
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2A69
| Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin | Descriptor: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | Authors: | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-07-02 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
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1YVZ
| Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor | Descriptor: | 3-[(2,4-DICHLOROBENZOYL)(ISOPROPYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION | Authors: | Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. | Deposit date: | 2005-02-16 | Release date: | 2005-03-22 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. J.Biol.Chem., 280, 2005
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1YVX
| Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor | Descriptor: | 3-[ISOPROPYL(4-METHYLBENZOYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION | Authors: | Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G. | Deposit date: | 2005-02-16 | Release date: | 2005-03-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors. J.Biol.Chem., 280, 2005
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6FO1
| Human R2TP subcomplex containing 1 RUVBL1-RUVBL2 hexamer bound to 1 RBD domain from RPAP3. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RNA polymerase II-associated protein 3, RuvB-like 1, ... | Authors: | Martino, F, Munoz-Hernandez, H, Rodriguez, C.F, Pearl, L.H, Llorca, O. | Deposit date: | 2018-02-05 | Release date: | 2018-04-04 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex. Nat Commun, 9, 2018
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2XI5
| N-terminal endonuclease domain of La Crosse virus L-protein | Descriptor: | MANGANESE (II) ION, RNA POLYMERASE L | Authors: | Reguera, J, Weber, F, Cusack, S. | Deposit date: | 2010-06-28 | Release date: | 2010-10-06 | Last modified: | 2012-07-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription. Plos Pathog., 6, 2010
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2XP1
| Structure of the tandem SH2 domains from Antonospora locustae transcription elongation factor Spt6 | Descriptor: | CHLORIDE ION, SPT6, SULFATE ION | Authors: | Diebold, M.-L, Koch, M, Cavarelli, J, Romier, C. | Deposit date: | 2010-08-24 | Release date: | 2010-09-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Noncanonical Tandem Sh2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase II. J.Biol.Chem., 285, 2010
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5CE7
| Structure of a non-canonical CID of Ctk3 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CTD kinase subunit gamma | Authors: | Muehlbacher, W, Mayer, A, Sun, M, Remmert, M, Cheung, A.C, Niesser, J, Soeding, J, Cramer, P. | Deposit date: | 2015-07-06 | Release date: | 2015-08-05 | Last modified: | 2015-09-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a noncanonical CTD-interacting domain fold. Proteins, 83, 2015
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3FDF
| Crystal structure of the serine phosphatase of RNA polymerase II CTD (SSU72 superfamily) from Drosophila melanogaster. Orthorhombic crystal form. Northeast Structural Genomics Consortium target FR253. | Descriptor: | FR253 | Authors: | Kuzin, A.P, Chen, Y, Seetharaman, J, Forouhar, F, Chinag, Y, Fang, Y, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-11-25 | Release date: | 2009-01-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Orthorombic crystal structure of serine phosphatase of rna polymerase ii ctd from fly drosofila melanogaster. northeast structural genomics consortium target fr253. To be Published
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5HCI
| GPN-loop GTPase Npa3 in complex with GDP | Descriptor: | GLYCEROL, GPN-loop GTPase 1, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. | Deposit date: | 2016-01-04 | Release date: | 2016-01-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly. Mol.Cell.Biol., 36, 2015
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5HCN
| GPN-loop GTPase Npa3 in complex with GMPPCP | Descriptor: | GLYCEROL, GPN-loop GTPase 1, LAURIC ACID, ... | Authors: | Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. | Deposit date: | 2016-01-04 | Release date: | 2016-01-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly. Mol.Cell.Biol., 36, 2015
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2PA8
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3OMX
| Crystal structure of Ssu72 with vanadate complex | Descriptor: | CG14216, VANADATE ION | Authors: | Zhang, Y, Zhang, M, Zhang, Y. | Deposit date: | 2010-08-27 | Release date: | 2011-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3366 Å) | Cite: | Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue. Biochem.J., 434, 2011
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