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5BWM
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BU of 5bwm by Molmil
The complex structure of C3cer exoenzyme and GDP bound RhoA (NADH-bound state)
Descriptor: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADP-ribosyltransferase, ...
Authors:Toda, A, Tsurumura, T, Yoshida, T, Tsuge, H.
Deposit date:2015-06-08
Release date:2015-06-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure.
J.Biol.Chem., 290, 2015
2N42
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BU of 2n42 by Molmil
EC-NMR Structure of Human H-RasT35S mutant protein Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data
Descriptor: GTPase HRas
Authors:Tang, Y, Huang, Y.J, Hopf, T.A, Sander, C, Marks, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-06-16
Release date:2015-07-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Protein structure determination by combining sparse NMR data with evolutionary couplings.
Nat.Methods, 12, 2015
4YON
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BU of 4yon by Molmil
P-Rex1:Rac1 complex
Descriptor: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, Ras-related C3 botulinum toxin substrate 1
Authors:Lucato, C.M, Whisstock, J.C, Ellisdon, A.M.
Deposit date:2015-03-11
Release date:2015-07-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.
J.Biol.Chem., 290, 2015
5BXQ
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BU of 5bxq by Molmil
Structure of the NTF2:RanGDP complex
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Stewart, M.
Deposit date:2015-06-09
Release date:2015-07-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for molecular recognition between nuclear transport factor 2 (NTF2) and the GDP-bound form of the Ras-family GTPase Ran.
J.Mol.Biol., 277, 1998
2N46
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BU of 2n46 by Molmil
EC-NMR Structure of Human H-RasT35S mutant protein Determined by Combining Evolutionary Couplings (EC) and Sparse NMR Data
Descriptor: GTPase HRas
Authors:Tang, Y, Huang, Y.J, Hopf, T.A, Sander, C, Marks, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-06-17
Release date:2015-07-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Protein structure determination by combining sparse NMR data with evolutionary couplings.
Nat.Methods, 12, 2015
4WVF
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BU of 4wvf by Molmil
Crystal structure of KPT276 in complex with CRM1-Ran-RanBP1
Descriptor: (2E)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-1-(3,3-difluoroazetidin-1-yl)prop-2-en-1-one, 1,2-ETHANEDIOL, CHLORIDE ION, ...
Authors:Sun, Q, Chook, Y.
Deposit date:2014-11-05
Release date:2015-07-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination.
Nat.Neurosci., 18, 2015
4XOI
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BU of 4xoi by Molmil
Structure of hsAnillin bound with RhoA(Q63L) at 2.1 Angstroms resolution
Descriptor: Actin-binding protein anillin, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Sun, L, Guan, R, Lee, I.-J, Liu, Y, Chen, M, Wang, J, Wu, J, Chen, Z.
Deposit date:2015-01-16
Release date:2015-07-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.092 Å)
Cite:Mechanistic insights into the anchorage of the contractile ring by anillin and mid1
Dev.Cell, 33, 2015
5A0F
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BU of 5a0f by Molmil
Crystal structure of Yersinia Afp18-modified RhoA
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, ...
Authors:Jank, T, Schimpl, M, van Aalten, D.M.
Deposit date:2015-04-20
Release date:2015-07-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Tyrosine glycosylation of Rho by Yersinia toxin impairs blastomere cell behaviour in zebrafish embryos.
Nat Commun, 6, 2015
4UJ5
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BU of 4uj5 by Molmil
Crystal structure of human Rab11-Rabin8-FIP3
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RAB-3A-INTERACTING PROTEIN, ...
Authors:Vetter, M, Lorentzen, E.
Deposit date:2015-04-08
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:Structure of Rab11-Fip3-Rabin8 Reveals Simultaneous Binding of Fip3 and Rabin8 Effectors to Rab11.
Nat.Struct.Mol.Biol., 22, 2015
4UJ4
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BU of 4uj4 by Molmil
Crystal structure of human Rab11-Rabin8-FIP3
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rab-3A-interacting protein, ...
Authors:Vetter, M, Lorentzen, E.
Deposit date:2015-04-08
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11.
Nat. Struct. Mol. Biol., 22, 2015
4UJ3
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BU of 4uj3 by Molmil
Crystal structure of human Rab11-Rabin8-FIP3
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RAB-3A-INTERACTING PROTEIN, ...
Authors:Vetter, M, Lorentzen, E.
Deposit date:2015-04-08
Release date:2015-08-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Rab11-Fip3-Rabin8 Reveals Simultaneous Binding of Fip3 and Rabin8 Effectors to Rab11.
Nat.Struct.Mol.Biol., 22, 2015
5CJ2
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BU of 5cj2 by Molmil
Ran GDP Y39A mutant triclinic crystal form
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Vetter, I.R, Brucker, S.
Deposit date:2015-07-13
Release date:2015-09-09
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Catalysis of GTP Hydrolysis by Small GTPases at Atomic Detail by Integration of X-ray Crystallography, Experimental, and Theoretical IR Spectroscopy.
J.Biol.Chem., 290, 2015
5CLQ
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BU of 5clq by Molmil
Ran Y39A in complex with GPPNHP and RanBD1
Descriptor: E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, MAGNESIUM ION, ...
Authors:Vetter, I.R, Brucker, S.
Deposit date:2015-07-16
Release date:2015-09-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Catalysis of GTP Hydrolysis by Small GTPases at Atomic Detail by Integration of X-ray Crystallography, Experimental, and Theoretical IR Spectroscopy.
J.Biol.Chem., 290, 2015
5CLL
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BU of 5cll by Molmil
Truncated Ran wild type in complex with GDP-BeF and RanBD1
Descriptor: BERYLLIUM TRIFLUORIDE ION, E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, ...
Authors:Vetter, I.R, Brucker, S.
Deposit date:2015-07-16
Release date:2015-09-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Catalysis of GTP Hydrolysis by Small GTPases at Atomic Detail by Integration of X-ray Crystallography, Experimental, and Theoretical IR Spectroscopy.
J.Biol.Chem., 290, 2015
5CIW
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BU of 5ciw by Molmil
Ran GDP Y39A mutant monoclinic crystal form
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Vetter, I.R, Brucker, S.
Deposit date:2015-07-13
Release date:2015-09-09
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Catalysis of GTP Hydrolysis by Small GTPases at Atomic Detail by Integration of X-ray Crystallography, Experimental, and Theoretical IR Spectroscopy.
J.Biol.Chem., 290, 2015
5CIQ
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BU of 5ciq by Molmil
Ran GDP wild type tetragonal crystal form
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Vetter, I.R, Brucker, S.
Deposit date:2015-07-13
Release date:2015-09-09
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Catalysis of GTP Hydrolysis by Small GTPases at Atomic Detail by Integration of X-ray Crystallography, Experimental, and Theoretical IR Spectroscopy.
J.Biol.Chem., 290, 2015
5CIT
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BU of 5cit by Molmil
Ran GDP wild type monoclinic crystal form
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Vetter, I.R, Brucker, S.
Deposit date:2015-07-13
Release date:2015-09-09
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Catalysis of GTP Hydrolysis by Small GTPases at Atomic Detail by Integration of X-ray Crystallography, Experimental, and Theoretical IR Spectroscopy.
J.Biol.Chem., 290, 2015
5DHA
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BU of 5dha by Molmil
Crystal Structure of CPEB4 NES Reverse Mutant Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Engineered Nuclear Export Signal Peptide (CPEB4 NES reverse mutant), Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y, Chook, Y.M.
Deposit date:2015-08-30
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DIF
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BU of 5dif by Molmil
Crystal Structure of CPEB4 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: CHLORIDE ION, Cytoplasmic polyadenylation element-binding protein 4, Exportin-1, ...
Authors:Fung, H.Y, Chook, Y.M.
Deposit date:2015-08-31
Release date:2015-09-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.092 Å)
Cite:Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DI9
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BU of 5di9 by Molmil
Crystal Structure of hRio2 NES Reverse Mutant Peptide in complex with CRM1-Ran-RanBP1
Descriptor: CHLORIDE ION, Engineered Nuclear Export Signal Peptide (hRio2 NES reverse mutant), Exportin-1, ...
Authors:Fung, H.Y, Chook, Y.M.
Deposit date:2015-08-31
Release date:2015-09-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DHF
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BU of 5dhf by Molmil
Crystal Structure of hRio2 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: CHLORIDE ION, Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y, Chook, Y.M.
Deposit date:2015-08-30
Release date:2015-09-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.285 Å)
Cite:Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DH9
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BU of 5dh9 by Molmil
Crystal Structure of PKI NES Flip Mutant Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Engineered Nuclear Export Signal Peptide (PKINES-Flip3 mutant), Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y, Chook, Y.M.
Deposit date:2015-08-30
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
4Z8Y
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BU of 4z8y by Molmil
Crystal structure of Rab GTPase Sec4p mutant - S29V
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein SEC4, ...
Authors:Rinadi, F.C, Collins, R.N.
Deposit date:2015-04-09
Release date:2015-10-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:New insights into the molecular mechanism of the Rab GTPase Sec4p activation.
Bmc Struct.Biol., 15, 2015
4ZDW
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BU of 4zdw by Molmil
Crystal structure of the Rab GTPase Sec4p mutant - S29V in complex with Sec2p and GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Rab guanine nucleotide exchange factor SEC2, Ras-related protein SEC4
Authors:Rinadi, F.C, Collins, R.N.
Deposit date:2015-04-20
Release date:2015-10-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:New insights into the molecular mechanism of the Rab GTPase Sec4p activation.
Bmc Struct.Biol., 15, 2015
5DIS
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BU of 5dis by Molmil
Crystal structure of a CRM1-RanGTP-SPN1 export complex bound to a 113 amino acid FG-repeat containing fragment of Nup214
Descriptor: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Monecke, T, Port, S.A, Dickmanns, A, Kehlenbach, R.H, Ficner, R.
Deposit date:2015-09-01
Release date:2015-11-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export.
Cell Rep, 13, 2015

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