Crystal structure of the Rab GTPase Sec4p mutant - S29V in complex with Sec2p and GDP

Summary for 4ZDW

DescriptorRas-related protein SEC4, Rab guanine nucleotide exchange factor SEC2, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywordsgtpase, gdp bound, rab sec4p, sec2p, gtp binding protein
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Total number of polymer chains3
Total molecular weight41712.46
Rinadi, F.C.,Collins, R.N. (deposition date: 2015-04-20, release date: 2015-10-14, Last modification date: 2019-12-25)
Primary citation
Rinaldi, F.C.,Packer, M.,Collins, R.
New insights into the molecular mechanism of the Rab GTPase Sec4p activation.
Bmc Struct.Biol., 15:14-14, 2015
PubMed: 26263895 (PDB entries with the same primary citation)
DOI: 10.1186/s12900-015-0041-5
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.292220.9%9.4%6.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload