4ZDW
Crystal structure of the Rab GTPase Sec4p mutant - S29V in complex with Sec2p and GDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ras-related protein SEC4 | polymer | 170 | 19134.9 | 1 | UniProt (P07560) Pfam (PF00071) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Suppressor of RHO3 protein 6 |
| 2 | B, C (B, C) | Rab guanine nucleotide exchange factor SEC2 | polymer | 93 | 11067.2 | 2 | UniProt (P17065) Pfam (PF06428) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | GDP-GTP exchange factor SEC2 |
| 3 | D (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A: 19 - 187 (UniProt: P07560)
B, C: 51 - 142 (UniProt: P17065)
| PDB | External Database | Details |
|---|---|---|
| Ser 18 | - | expression tag |
| Val 29 | Ser 29 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 50 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 41269.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 443.2 | |
| All* | Total formula weight | 41712.5 |
