5DH9

Crystal Structure of PKI NES Flip Mutant Peptide in complex with CRM1-Ran-RanBP1

Summary for 5DH9

• Entry DOI: 10.2210/pdb5dh9/pdb
• Related: 5DHA 5DHF
• Descriptor: GTP-binding nuclear protein Ran, Ran-specific GTPase-activating protein 1, Exportin-1, ... (8 entities in total)
• Functional Keywords: peptides, heat repeat, nuclear export signal, exportin-1, nuclear transport, transport protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 163721.42

Authors

Fung, H.Y.,Chook, Y.M. (deposition date: 2015-08-30, release date: 2015-09-16, Last modification date: 2023-09-27)

• Primary citation: Fung, H.Y.,Fu, S.C.,Brautigam, C.A.,Chook, Y.M.; Structural determinants of nuclear export signal orientation in binding to exportin CRM1.; Elife, 4:-, 2015; PubMed: 26349033; DOI: 10.7554/eLife.10034

Experimental method

X-RAY DIFFRACTION (2.55 Å)