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2KRB
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BU of 2krb by Molmil
Solution structure of EIF3B-RRM bound to EIF3J peptide
Descriptor: Eukaryotic translation initiation factor 3 subunit B, Eukaryotic translation initiation factor 3 subunit J
Authors:Elantak, L, Wagner, S, Herrmannova, A, Janoskova, M, Rutkai, E, Lukavsky, P.J, Valasek, L.
Deposit date:2009-12-16
Release date:2010-01-05
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The indispensable N-terminal half of eIF3j/HCR1 co-operates with its structurally conserved binding partner eIF3b/PRT1-RRM and eIF1A in stringent AUG selection
To be Published
2KYX
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BU of 2kyx by Molmil
Solution structure of the RRM domain of CYP33
Descriptor: Peptidyl-prolyl cis-trans isomerase E
Authors:Park, S, Bushweller, J.H.
Deposit date:2010-06-09
Release date:2010-08-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression .
Biochemistry, 49, 2010
2LYV
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BU of 2lyv by Molmil
Solution structure of the two RRM domains of hnRNP A1 (UP1) using segmental isotope labeling
Descriptor: Heterogeneous nuclear ribonucleoprotein A1
Authors:Barraud, P, Allain, F.H.-T.
Deposit date:2012-09-19
Release date:2012-12-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of the two RNA recognition motifs of hnRNP A1 using segmental isotope labeling: how the relative orientation between RRMs influences the nucleic acid binding topology.
J.Biomol.Nmr, 55, 2013
2MHN
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BU of 2mhn by Molmil
NMR structure of the first RRM domain of the protein RBM39 from Homo sapiens
Descriptor: RNA-binding protein 39
Authors:Serrano, P, Geralt, M, Dutta, S.K, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2013-12-02
Release date:2014-01-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of the first RRM domain of the protein RBM39 from Homo sapiens
To be Published
2MGZ
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BU of 2mgz by Molmil
Solution structure of RBFOX family ASD-1 RRM and SUP-12 RRM in ternary complex with RNA
Descriptor: Protein ASD-1, isoform a, Protein SUP-12, ...
Authors:Takahashi, M, Kuwasako, K, Unzai, S, Tsuda, K, Yoshikawa, S, He, F, Kobayashi, N, Guntert, P, Shirouzu, M, Ito, T, Tanaka, A, Yokoyama, S, Hagiwara, M, Kuroyanagi, H, Muto, Y.
Deposit date:2013-11-12
Release date:2014-08-13
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:RBFOX and SUP-12 sandwich a G base to cooperatively regulate tissue-specific splicing
Nat.Struct.Mol.Biol., 21, 2014
2MB0
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BU of 2mb0 by Molmil
Solution structure of hnRNP G RRM in complex with the RNA 5'-AUCAAA-3'
Descriptor: RNA-binding motif protein, X chromosome, RNA_(5'-R(*AP*UP*CP*AP*AP*A)-3')
Authors:Moursy, A, Allain, F.H.-T, Clery, A.
Deposit date:2013-07-22
Release date:2014-04-09
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Characterization of the RNA recognition mode of hnRNP G extends its role in SMN2 splicing regulation.
Nucleic Acids Res., 42, 2014
2MKC
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BU of 2mkc by Molmil
Cooperative Structure of the Heterotrimeric pre-mRNA Retention and Splicing Complex
Descriptor: Pre-mRNA leakage protein 1, Pre-mRNA-splicing factor CWC26, U2 snRNP component IST3
Authors:Wysoczanski, P, Schneider, C, Xiang, S, Munari, F, Trowitzsch, S, Wahl, M.C, Luhrmann, R, Becker, S, Zweckstetter, M.
Deposit date:2014-02-04
Release date:2014-09-03
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex.
Nat.Struct.Mol.Biol., 21, 2014
2M52
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BU of 2m52 by Molmil
NMR Structure of the third RNA Recognition Motif (RRM) of U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
Descriptor: Splicing factor U2AF 65 kDa subunit
Authors:Dutta, S.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2013-02-12
Release date:2013-03-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR Structure of the third RNA Recognition Motif (RRM) of U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
To be Published
2LXU
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BU of 2lxu by Molmil
Solution NMR Structure of the eukaryotic RNA recognition motif, RRM1, from the heterogeneous nuclear ribonucleoprotein H from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8614A
Descriptor: Heterogeneous nuclear ribonucleoprotein H
Authors:Ramelot, T.A, Yang, Y, Pederson, K, Shastry, R, Kohan, E, Janjua, H, Xiao, R, Acton, T.B, Everett, J.K, Prestegard, J.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-08-31
Release date:2012-10-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR Structure of the eukaryotic RNA recognition motif, RRM1, from the heterogeneous nuclear ribonucleoprotein H from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8614A
To be Published
2M7S
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BU of 2m7s by Molmil
NMR structure of RNA recognition motif 2 (RRM2) of Homo sapiens splicing factor, arginine/serine-rich 1
Descriptor: Serine/arginine-rich splicing factor 1
Authors:Dutta, S.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2013-04-29
Release date:2013-05-15
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of RNA recognition motif 2 (RRM2) of Homo sapiens splicing factor, arginine/serine-rich 1
To be Published
2MJN
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BU of 2mjn by Molmil
Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1
Descriptor: Nucleolysin TIA-1 isoform p40
Authors:Sattler, M, Wang, I.
Deposit date:2014-01-13
Release date:2014-04-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1.
Nucleic Acids Res., 42, 2014
2M8H
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BU of 2m8h by Molmil
RRM domain of human RBM7
Descriptor: RNA-binding protein 7
Authors:Sikorsky, T, Hrossova, D, Vanacova, S, Stefl, R.
Deposit date:2013-05-21
Release date:2015-01-28
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:RNA binding properties of the human NEXT complex
To be Published
2MMY
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BU of 2mmy by Molmil
Solution structure of the RNA recognition motif of human TAF15
Descriptor: TATA-binding protein-associated factor 2N
Authors:Kashyap, M, Ganguly, A.K, Bhavesh, N.S.
Deposit date:2014-03-22
Release date:2015-03-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural delineation of stem-loop RNA binding by human TAF15 protein
Sci Rep, 5, 2015
5FJ4
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BU of 5fj4 by Molmil
Structure of the standard kink turn HmKt-7 as stem loop bound with U1A and L7Ae proteins
Descriptor: 50S RIBOSOMAL PROTEIN L7AE, HMKT-7, U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A
Authors:Huang, L, Lilley, D.M.J.
Deposit date:2015-10-06
Release date:2016-05-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A Critical Base Pair in K-Turns Determines the Conformational Class Adopted, and Correlates with Biological Function.
Nucleic Acids Res., 44, 2016
3EX7
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BU of 3ex7 by Molmil
The crystal structure of EJC in its transition state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Eukaryotic initiation factor 4A-III, ...
Authors:Andersen, G.R, Nielsen, K.H.
Deposit date:2008-10-16
Release date:2008-12-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Mechanism of ATP turnover inhibition in the EJC
Rna, 15, 2009
7EVO
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BU of 7evo by Molmil
The cryo-EM structure of the human 17S U2 snRNP
Descriptor: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, RNA helicase, ...
Authors:Zhang, X, Zhan, X, Shi, Y.
Deposit date:2021-05-21
Release date:2022-08-03
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural insights into branch site proofreading by human spliceosome.
Nat.Struct.Mol.Biol., 2024
2VOO
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BU of 2voo by Molmil
Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer UUUUUUUU
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP)-3', LUPUS LA PROTEIN
Authors:Kotik-Kogan, O, Valentine, E.R, Sanfelice, D, Conte, M.R, Curry, S.
Deposit date:2008-02-19
Release date:2008-05-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3' Ends by the Human La Protein.
Structure, 16, 2008
6D0Y
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BU of 6d0y by Molmil
X-ray Crystal Structure of PGC-1beta C-terminus bound to the CBP80-CBP20 Cap Binding Complex
Descriptor: MAGNESIUM ION, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ...
Authors:Gleghorn, M.L, Maquat, L.E.
Deposit date:2018-04-11
Release date:2018-04-25
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.676 Å)
Cite:Transcriptional coactivator PGC-1 alpha contains a novel CBP80-binding motif that orchestrates efficient target gene expression.
Genes Dev., 32, 2018
2J0S
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BU of 2j0s by Molmil
The crystal structure of the Exon Junction Complex at 2.2 A resolution
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP *UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ...
Authors:Bono, F, Ebert, J, Lorentzen, E, Conti, E.
Deposit date:2006-08-04
Release date:2006-09-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:The Crystal Structure of the Exon Junction Complex Reveals How It Mantains a Stable Grip on Mrna
Cell(Cambridge,Mass.), 126, 2006
2J0Q
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BU of 2j0q by Molmil
The crystal structure of the Exon Junction Complex at 3.2 A resolution
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ...
Authors:Bono, F, Ebert, J, Lorentzen, E, Conti, E.
Deposit date:2006-08-04
Release date:2006-08-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Crystal Structure of the Exon Junction Complex Reveals How It Maintains a Stable Grip on Mrna.
Cell(Cambridge,Mass.), 126, 2006
5MMM
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BU of 5mmm by Molmil
Structure of the 70S chloroplast ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein 2, ...
Authors:Bieri, P, Leibundgut, M, Saurer, M, Boehringer, D, Ban, N.
Deposit date:2016-12-11
Release date:2017-01-11
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The complete structure of the chloroplast 70S ribosome in complex with translation factor pY.
EMBO J., 36, 2017
5MDU
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BU of 5mdu by Molmil
Structure of the RNA recognition motif (RRM) of Seb1 from S. pombe.
Descriptor: CHLORIDE ION, GLYCEROL, Rpb7-binding protein seb1, ...
Authors:Wittmann, S, Renner, M, El Omari, K, Adams, O, Vasiljeva, L, Grimes, J.
Deposit date:2016-11-13
Release date:2017-04-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA.
Nat Commun, 8, 2017
6UD7
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BU of 6ud7 by Molmil
Crystal structure of full-length human DCAF15-DDB1(deltaBPB)-DDA1-RBM39 in complex with indisulam
Descriptor: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1,DNA damage-binding protein 1, ...
Authors:Bussiere, D.E, Shu, W, Xie, L, Knapp, M.
Deposit date:2019-09-18
Release date:2019-12-18
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat.Chem.Biol., 16, 2020
6UE5
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BU of 6ue5 by Molmil
Crystal structure of full-length human DCAF15-DDB1-deltaPBP-DDA1-RBM39 in complex with 4-(aminomethyl)-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide
Descriptor: 4-(aminomethyl)-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, ...
Authors:Knapp, M.S, Shu, W, Xie, L, Bussiere, D.E.
Deposit date:2019-09-20
Release date:2019-12-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat.Chem.Biol., 16, 2020
1A9N
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BU of 1a9n by Molmil
CRYSTAL STRUCTURE OF THE SPLICEOSOMAL U2B''-U2A' PROTEIN COMPLEX BOUND TO A FRAGMENT OF U2 SMALL NUCLEAR RNA
Descriptor: RNA (5'-R(*CP*CP*UP*GP*GP*UP*AP*UP*UP*GP*CP*AP*GP*UP*AP*CP*CP*UP*CP*CP*AP*GP* GP*U)-3'), SPLICEOSOMAL U2B'', U2A'
Authors:Price, S.R, Evans, P.R, Nagai, K.
Deposit date:1998-04-08
Release date:1998-09-23
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of the spliceosomal U2B"-U2A' protein complex bound to a fragment of U2 small nuclear RNA.
Nature, 394, 1998

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