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3AY5
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BU of 3ay5 by Molmil
Crystal structure of HHM (human homologue of murine maternal Id-like molecule)
Descriptor: Cyclin-D1-binding protein 1
Authors:Seto, A, Ishitani, R, Nureki, O.
Deposit date:2011-04-28
Release date:2012-03-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of autoinhibition.
Embo J., 31, 2012
2YPB
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BU of 2ypb by Molmil
Structure of the SCL:E47 complex bound to DNA
Descriptor: EBOX FORWARD, EBOX REVERSE, T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1, ...
Authors:El Omari, K, Hoosdally, S.J, Tuladhar, K, Karia, D, Ponsele, E, Platonova, O, Vyas, P, Patient, R, Porcher, C, Mancini, E.J.
Deposit date:2012-10-30
Release date:2013-07-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
Cell Rep., 4, 2013
2YPA
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Structure of the SCL:E47:LMO2:LDB1 complex bound to DNA
Descriptor: EBOX FORWARD, EBOX REVERSE, LIM DOMAIN-BINDING PROTEIN 1, ...
Authors:El Omari, K, Hoosdally, S.J, Tuladhar, K, Karia, D, Ponsele, E, Platonova, O, Vyas, P, Patient, R, Porcher, C, Mancini, E.J.
Deposit date:2012-10-30
Release date:2013-07-31
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
Cell Rep., 4, 2013
2VRR
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BU of 2vrr by Molmil
Structure of SUMO modified Ubc9
Descriptor: FORMIC ACID, SMALL UBIQUITIN-RELATED MODIFIER 1, SODIUM ION, ...
Authors:Knipscheer, P, Flotho, A, Klug, H, Olsen, J.V, van Dijk, W.J, Fish, A, Johnson, E.S, Mann, M, Sixma, T.K, Pichler, A.
Deposit date:2008-04-13
Release date:2008-08-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Ubc9 sumoylation regulates SUMO target discrimination.
Mol. Cell, 31, 2008
2UYZ
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BU of 2uyz by Molmil
Non-covalent complex between Ubc9 and SUMO1
Descriptor: SMALL UBIQUITIN-RELATED MODIFIER 1, SODIUM ION, SUMO-CONJUGATING ENZYME UBC9
Authors:Knipscheer, P, van Dijk, W.J, Olsen, J.V, Mann, M, Sixma, T.K.
Deposit date:2007-04-21
Release date:2007-06-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation.
EMBO J., 26, 2007
2QL2
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BU of 2ql2 by Molmil
Crystal Structure of the basic-helix-loop-helix domains of the heterodimer E47/NeuroD1 bound to DNA
Descriptor: DNA (5'-D(*DAP*DGP*DGP*DAP*DCP*DCP*DAP*DGP*DAP*DTP*DGP*DGP*DCP*DCP*DTP*DA)-3'), DNA (5'-D(*DTP*DAP*DGP*DGP*DCP*DCP*DAP*DTP*DCP*DTP*DGP*DGP*DTP*DCP*DCP*DT)-3'), Neurogenic differentiation factor 1, ...
Authors:Rose, R.B, Longo, A, Guanga, G.P.
Deposit date:2007-07-12
Release date:2008-11-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition.
Biochemistry, 47, 2008
2MJV
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BU of 2mjv by Molmil
Solution structures of second bromodomain of Brd4 with di-acetylated Twist peptide
Descriptor: Bromodomain-containing protein 4, Twist-related protein 1
Authors:Zeng, L, Zhou, M.
Deposit date:2014-01-16
Release date:2014-03-19
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Disrupting the Interaction of BRD4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer.
Cancer Cell, 25, 2014
2MH3
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BU of 2mh3 by Molmil
NMR structure of the basic helix-loop-helix region of the transcriptional repressor HES-1
Descriptor: Transcription factor HES-1
Authors:Wienk, H, Popovic, M, Coglievina, M, Boelens, R, Pongor, S, Pintar, A.
Deposit date:2013-11-15
Release date:2014-02-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The basic helix-loop-helix region of the transcriptional repressor hairy and enhancer of split 1 is preorganized to bind DNA.
Proteins, 82, 2014
2MH0
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BU of 2mh0 by Molmil
Solution NMR structure of the p300 Taz2:ETAD1 complex
Descriptor: Histone acetyltransferase p300, Transcription factor E2-alpha
Authors:Langelaan, D.N, Smith, S.P, Chitayat, S.
Deposit date:2013-11-12
Release date:2014-11-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural insights into TAZ2 domain-mediated CBP/p300 recruitment by transactivation domain 1 of the lymphopoietic transcription factor E2A.
J.Biol.Chem., 295, 2020
2LFH
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BU of 2lfh by Molmil
Solution NMR Structure of the Helix-loop-Helix Domain of Human ID3 Protein, Northeast Structural Genomics Consortium Target HR3111A
Descriptor: DNA-binding protein inhibitor ID-3
Authors:Eletsky, A, Wang, D, Kohan, E, Janjua, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-06-30
Release date:2011-07-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR Structure of the Helix-loop-Helix Domain of Human ID3 Protein, Northeast Structural Genomics Consortium Target HR3111A
To be Published
2KWF
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BU of 2kwf by Molmil
The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1
Descriptor: CREB-binding protein, Transcription factor 4
Authors:Denis, C.M, Chitayat, S, Plevin, M.J, Liu, S, Spencer, H.L, Ikura, M, LeBrun, D.P, Smith, S.P.
Deposit date:2010-04-08
Release date:2011-07-20
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1
To be Published
2K7S
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BU of 2k7s by Molmil
Human ARNT C-Terminal PAS Domain, 3 Residue IB slip
Descriptor: Aryl hydrocarbon receptor nuclear translocator
Authors:Evans, M.R, Card, P.B, Gardner, K.H.
Deposit date:2008-08-20
Release date:2009-01-20
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:ARNT PAS-B has a fragile native state structure with an alternative beta-sheet register nearby in sequence space
Proc.Natl.Acad.Sci.USA, 106, 2009
2A24
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BU of 2a24 by Molmil
HADDOCK Structure of HIF-2a/ARNT PAS-B Heterodimer
Descriptor: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain protein 1
Authors:Card, P.B, Erbel, P.J, Gardner, K.H.
Deposit date:2005-06-21
Release date:2006-01-17
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization.
J.Mol.Biol., 353, 2005
1X0O
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BU of 1x0o by Molmil
human ARNT C-terminal PAS domain
Descriptor: Aryl hydrocarbon receptor nuclear translocator
Authors:Card, P.B, Erbel, P.J, Gardner, K.H.
Deposit date:2005-03-25
Release date:2005-10-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural Basis of ARNT PAS-B Dimerization: Use of a Common Beta-sheet Interface for Hetero- and Homodimerization.
J.Mol.Biol., 353, 2005
1U9B
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BU of 1u9b by Molmil
MURINE/HUMAN UBIQUITIN-CONJUGATING ENZYME UBC9
Descriptor: UBIQUITIN-CONJUGATING ENZYME E9
Authors:Tong, H, Hateboer, G, Perrakis, A, Bernards, R, Sixma, T.K.
Deposit date:1997-05-20
Release date:1997-07-07
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system.
J.Biol.Chem., 272, 1997
1U9A
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BU of 1u9a by Molmil
HUMAN UBIQUITIN-CONJUGATING ENZYME UBC9
Descriptor: UBIQUITIN-CONJUGATING ENZYME
Authors:Tong, H, Hateboer, G, Perrakis, A, Bernards, R, Sixma, T.K.
Deposit date:1997-02-11
Release date:1997-05-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system.
J.Biol.Chem., 272, 1997
1NLW
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BU of 1nlw by Molmil
Crystal structure of Mad-Max recognizing DNA
Descriptor: 5'-D(*GP*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*TP*C)-3', MAD PROTEIN, MAX PROTEIN
Authors:Nair, S.K, Burley, S.K.
Deposit date:2003-01-07
Release date:2003-02-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structures of Myc-Max and Mad-Max recognizing DNA: Molecular bases of regulation by proto-oncogenic transcription factors
Cell(Cambridge,Mass.), 112, 2003
1NKP
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BU of 1nkp by Molmil
Crystal structure of Myc-Max recognizing DNA
Descriptor: 5'-D(*CP*GP*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*TP*C)-3', Max protein, Myc proto-oncogene protein
Authors:Nair, S.K, Burley, S.K.
Deposit date:2003-01-03
Release date:2003-02-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray structures of Myc-Max and Mad-Max recognizing DNA: Molecular bases of regulation by proto-oncogenic transcription factors
Cell(Cambridge,Mass.), 112, 2003
1MDY
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BU of 1mdy by Molmil
CRYSTAL STRUCTURE OF MYOD BHLH DOMAIN BOUND TO DNA: PERSPECTIVES ON DNA RECOGNITION AND IMPLICATIONS FOR TRANSCRIPTIONAL ACTIVATION
Descriptor: DNA (5'-D(*TP*CP*AP*AP*CP*AP*GP*CP*TP*GP*TP*TP*GP*A)-3'), PROTEIN (MYOD BHLH DOMAIN)
Authors:Ma, P.C.M, Rould, M.A, Weintraub, H, Pabo, C.O.
Deposit date:1994-06-09
Release date:1994-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of MyoD bHLH domain-DNA complex: perspectives on DNA recognition and implications for transcriptional activation.
Cell(Cambridge,Mass.), 77, 1994
1HLO
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BU of 1hlo by Molmil
THE CRYSTAL STRUCTURE OF AN INTACT HUMAN MAX-DNA COMPLEX: NEW INSIGHTS INTO MECHANISMS OF TRANSCRIPTIONAL CONTROL
Descriptor: DNA (5'-D(*AP*CP*CP*AP*CP*GP*TP*GP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*CP*AP*CP*GP*TP*GP*GP*T)-3'), PROTEIN (TRANSCRIPTION FACTOR MAX)
Authors:Brownlie, P, Ceska, T.A, Lamers, M, Romier, C, Theo, H, Suck, D.
Deposit date:1997-09-10
Release date:1997-10-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of an intact human Max-DNA complex: new insights into mechanisms of transcriptional control.
Structure, 5, 1997
1A0A
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BU of 1a0a by Molmil
PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4/DNA COMPLEX
Descriptor: DNA (5'-D(*CP*TP*AP*GP*TP*CP*CP*CP*AP*CP*GP*TP*GP*TP*GP*AP*G )-3'), DNA (5'-D(*CP*TP*CP*AP*CP*AP*CP*GP*TP*GP*GP*GP*AP*CP*TP*AP*G )-3'), PROTEIN (PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4)
Authors:Shimizu, T, Toumoto, A, Ihara, K, Shimizu, M, Kyogoku, Y, Ogawa, N, Oshima, Y, Hakoshima, T.
Deposit date:1997-11-27
Release date:1998-03-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition.
EMBO J., 16, 1997

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