1P6S
| Solution Structure of the Pleckstrin Homology Domain of Human Protein Kinase B beta (Pkb/Akt) | Descriptor: | RAC-beta serine/threonine protein kinase | Authors: | Auguin, D, Barthe, P, Auge-Senegas, M.T, Stern, M.H, Noguchi, M, Roumestand, C. | Deposit date: | 2003-04-30 | Release date: | 2004-05-18 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure and backbone dynamics of the pleckstrin homology domain of the human
protein kinase B (PKB/Akt). Interaction with inositol phosphates. J.BIOMOL.NMR, 28, 2004
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6BNM
| Crystal Structure of the P-Rex2 PH domain | Descriptor: | CHLORIDE ION, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein | Authors: | Cash, J.N, Sharma, P.V, Tesmer, J.J.G. | Deposit date: | 2017-11-17 | Release date: | 2018-11-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and biochemical characterization of the pleckstrin homology domain of the RhoGEF P-Rex2 and its regulation by PIP3. J.Struct.Biol., 1, 2019
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1PLS
| SOLUTION STRUCTURE OF A PLECKSTRIN HOMOLOGY DOMAIN | Descriptor: | PLECKSTRIN HOMOLOGY DOMAIN | Authors: | Yoon, H.S, Hajduk, P.J, Petros, A.M, Olejniczak, E.T, Meadows, R.P, Fesik, S.W. | Deposit date: | 1994-05-03 | Release date: | 1995-06-03 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of a pleckstrin-homology domain. Nature, 369, 1994
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1PMS
| PLECKSTRIN HOMOLOGY DOMAIN OF SON OF SEVENLESS 1 (SOS1) WITH GLYCINE-SERINE ADDED TO THE N-TERMINUS, NMR, 20 STRUCTURES | Descriptor: | SOS 1 | Authors: | Koshiba, S, Kigawa, T, Kim, J, Shirouzu, M, Bowtell, D, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 1997-02-18 | Release date: | 1997-05-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The solution structure of the pleckstrin homology domain of mouse Son-of-sevenless 1 (mSos1). J.Mol.Biol., 269, 1997
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1U5F
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1U5E
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1DYN
| CRYSTAL STRUCTURE AT 2.2 ANGSTROMS RESOLUTION OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM HUMAN DYNAMIN | Descriptor: | DYNAMIN | Authors: | Ferguson, K.M, Lemmon, M.A, Schlessinger, J, Sigler, P.B. | Deposit date: | 1994-12-21 | Release date: | 1995-02-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure at 2.2 A resolution of the pleckstrin homology domain from human dynamin. Cell(Cambridge,Mass.), 79, 1994
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1DRO
| NMR STRUCTURE OF THE CYTOSKELETON/SIGNAL TRANSDUCTION PROTEIN | Descriptor: | BETA-SPECTRIN | Authors: | Zhang, P, Talluri, S, Deng, H, Branton, D, Wagner, G. | Deposit date: | 1995-09-29 | Release date: | 1996-04-03 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the pleckstrin homology domain of Drosophila beta-spectrin. Structure, 3, 1995
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1EAZ
| Crystal structure of the phosphoinositol (3,4)-bisphosphate binding PH domain of TAPP1 from human. | Descriptor: | CITRIC ACID, TANDEM PH DOMAIN CONTAINING PROTEIN-1 | Authors: | Thomas, C.C, Dowler, S, Deak, M, Alessi, D.R, Van Aalten, D.M.F. | Deposit date: | 2001-07-17 | Release date: | 2002-07-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal Structure of the Phosphatidylinositol 3,4-Bisphosphate-Binding Pleckstrin Homology (Ph) Domain of Tandem Ph-Domain-Containing Protein 1 (Tapp1): Molecular Basis of Lipid Specificity Biochem.J., 358, 2001
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1FGY
| GRP1 PH DOMAIN WITH INS(1,3,4,5)P4 | Descriptor: | GRP1, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE | Authors: | Lietzke, S.E, Bose, S, Cronin, T, Klarlund, J, Chawla, A, Czech, M.P, Lambright, D.G. | Deposit date: | 2000-07-29 | Release date: | 2000-08-23 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis of 3-phosphoinositide recognition by pleckstrin homology domains. Mol.Cell, 6, 2000
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1FAO
| STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM DAPP1/PHISH IN COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE | Descriptor: | DUAL ADAPTOR OF PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDES, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE | Authors: | Ferguson, K.M, Kavran, J.M, Sankaran, V.G, Fournier, E, Isakoff, S.J, Skolnik, E.Y, Lemmon, M.A. | Deposit date: | 2000-07-13 | Release date: | 2000-07-20 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains. Mol.Cell, 6, 2000
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1FHX
| Structure of the pleckstrin homology domain from GRP1 in complex with inositol 1,3,4,5-tetrakisphosphate | Descriptor: | GUANINE NUCLEOTIDE EXCHANGE FACTOR AND INTEGRIN BINDING PROTEIN HOMOLOG GRP1, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, SULFATE ION | Authors: | Ferguson, K.M, Kavran, J.M, Sankaran, V.G, Fournier, E, Isakoff, S.J, Skolnik, E.Y, Lemmon, M.A. | Deposit date: | 2000-08-02 | Release date: | 2000-08-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains Mol.Cell, 6, 2000
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1FGZ
| GRP1 PH DOMAIN (UNLIGANDED) | Descriptor: | GRP1, SULFATE ION | Authors: | Lietzke, S.E, Bose, S, Cronin, T, Klarlund, J, Chawla, A, Czech, M.P, Lambright, D.G. | Deposit date: | 2000-07-29 | Release date: | 2000-08-23 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis of 3-phosphoinositide recognition by pleckstrin homology domains. Mol.Cell, 6, 2000
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1FB8
| STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM DAPP1/PHISH | Descriptor: | DUAL ADAPTOR OF PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDES, PHOSPHATE ION | Authors: | Ferguson, K.M, Kavran, J.M, Sankaran, V.G, Fournier, E, Isakoff, S.J, Skolnik, E.Y, Lemmon, M.A. | Deposit date: | 2000-07-14 | Release date: | 2000-07-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains. Mol.Cell, 6, 2000
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1FHW
| Structure of the pleckstrin homology domain from GRP1 in complex with inositol(1,3,4,5,6)pentakisphosphate | Descriptor: | GUANINE NUCLEOTIDE EXCHANGE FACTOR AND INTEGRIN BINDING PROTEIN HOMOLOG GRP1, INOSITOL-(1,3,4,5,6)-PENTAKISPHOSPHATE, SULFATE ION | Authors: | Ferguson, K.M, Kavran, J.M, Sankaran, V.G, Fournier, E, Isakoff, S.J, Skolnik, E.Y, Lemmon, M.A. | Deposit date: | 2000-08-02 | Release date: | 2000-08-23 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains Mol.Cell, 6, 2000
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1H10
| HIGH RESOLUTION STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN OF PROTEIN KINASE B/AKT BOUND TO INS(1,3,4,5)-TETRAKISPHOPHATE | Descriptor: | INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, RAC-ALPHA SERINE/THREONINE KINASE | Authors: | Thomas, C.C, Deak, M, Alessi, D.R, Van Aalten, D.M.F. | Deposit date: | 2002-07-01 | Release date: | 2003-06-27 | Last modified: | 2019-05-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | High Resolution Structure of the Pleckstrin Homology Domain of Protein Kinase B/Akt Bound to Phosphatidylinositol (3,4,5)-Trisphosphate Curr.Biol., 12, 2002
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3TFM
| Myosin X PH1N-PH2-PH1C tandem | Descriptor: | Myosin X, PHOSPHATE ION | Authors: | Yu, J, Lu, Q, Yan, J, Wei, Z, Zhang, M. | Deposit date: | 2011-08-16 | Release date: | 2011-12-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensor MOLECULAR BIOLOGY OF THE CELL, 22, 2011
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4HHV
| Crystal structure of ceramide transfer protein pleckstrin homology domain | Descriptor: | ACETATE ION, CHLORIDE ION, Collagen type IV alpha-3-binding protein, ... | Authors: | Prashek, J, Truong, T, Yao, X. | Deposit date: | 2012-10-10 | Release date: | 2013-11-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structure of the Pleckstrin Homology Domain from the Ceramide Transfer Protein: Implications for Conformational Change upon Ligand Binding. Plos One, 8, 2013
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3VIA
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4A6K
| Crystal structure of Slm1-PH domain in complex with D-myo-Inositol-4- phosphate | Descriptor: | D-MYO-INOSITOL-4-PHOSPHATE, PHOSPHATE ION, PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE-BINDING PROTEIN SLM1 | Authors: | Anand, K, Maeda, K, Gavin, A.C. | Deposit date: | 2011-11-04 | Release date: | 2012-06-13 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Analyses of Slm1-Ph Domain Demonstrate Ligand Binding in the Non-Canonical Site Plos One, 7, 2012
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4A6F
| Crystal structure of Slm1-PH domain in complex with Phosphoserine | Descriptor: | PHOSPHATE ION, PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE-BINDING PROTEIN SLM1, PHOSPHOSERINE | Authors: | Anand, K, Maeda, K, Gavin, A.C. | Deposit date: | 2011-11-02 | Release date: | 2012-06-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural Analyses of Slm1-Ph Domain Demonstrate Ligand Binding in the Non-Canonical Site Plos One, 7, 2012
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4A5K
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2P0F
| ArhGAP9 PH domain in complex with Ins(1,3,5)P3 | Descriptor: | PHOSPHATE ION, Rho GTPase-activating protein 9 | Authors: | Ceccarelli, D.F.J, Blasutig, I, Goudreault, M, Ruston, J, Pawson, T, Sicheri, F. | Deposit date: | 2007-02-28 | Release date: | 2007-03-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Non-canonical Interaction of Phosphoinositides with Pleckstrin Homology Domains of Tiam1 and ArhGAP9. J.Biol.Chem., 282, 2007
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2OTX
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2P0H
| ArhGAP9 PH domain in complex with Ins(1,3,4)P3 | Descriptor: | (1S,3S,4S)-1,3,4-TRIPHOSPHO-MYO-INOSITOL, Rho GTPase-activating protein 9 | Authors: | Ceccarelli, D.F.J, Blasutig, I, Goudreault, M, Ruston, J, Pawson, T, Sicheri, F. | Deposit date: | 2007-02-28 | Release date: | 2007-03-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Non-canonical Interaction of Phosphoinositides with Pleckstrin Homology Domains of Tiam1 and ArhGAP9. J.Biol.Chem., 282, 2007
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