1EAZ

Crystal structure of the phosphoinositol (3,4)-bisphosphate binding PH domain of TAPP1 from human.

Summary for 1EAZ

Entry DOI	10.2210/pdb1eaz/pdb
Descriptor	TANDEM PH DOMAIN CONTAINING PROTEIN-1, CITRIC ACID (3 entities in total)
Functional Keywords	lipid-binding protein, lipid degradation, ph domain, phosphatidylinositol (3, 4)-bisphosphate, signalling, lipid binding protein
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	14432.43
Authors	Thomas, C.C.,Dowler, S.,Deak, M.,Alessi, D.R.,Van Aalten, D.M.F. (deposition date: 2001-07-17, release date: 2002-07-11, Last modification date: 2023-12-13)
Primary citation	Thomas, C.C.,Dowler, S.,Deak, M.,Alessi, D.R.,Van Aalten, D.M.F. Crystal Structure of the Phosphatidylinositol 3,4-Bisphosphate-Binding Pleckstrin Homology (Ph) Domain of Tandem Ph-Domain-Containing Protein 1 (Tapp1): Molecular Basis of Lipid Specificity Biochem.J., 358:287-, 2001 Cited by PubMed: 11513726 DOI: 10.1042/0264-6021:3580287 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation