2OTX

Crystal Structure of A N-terminal Fragment of SKAP-HOM Containing both the Helical Dimerization Domain and the PH Domain

Summary for 2OTX

• Entry DOI: 10.2210/pdb2otx/pdb
• Related: 1U5D 1U5F 1U5G
• Descriptor: Src kinase-associated phosphoprotein 2 (2 entities in total)
• Functional Keywords: novel dimerization domain, ph domain, signaling protein
• Biological source: Mus musculus (house mouse)
• Cellular location: Cytoplasm: Q3UND0
• Total number of polymer chains: 2
• Total formula weight: 48343.96

Authors

Tang, Y.,Swanson, K.D.,Neel, B.G.,Eck, M.J. (deposition date: 2007-02-09, release date: 2007-03-27, Last modification date: 2023-08-30)

• Primary citation: Swanson, K.D.,Tang, Y.,Ceccarelli, D.F.,Poy, F.,Sliwa, J.P.,Neel, B.G.,Eck, M.J.; The Skap-hom dimerization and PH domains comprise a 3'-phosphoinositide-gated molecular switch.; Mol.Cell, 32:564-575, 2008; PubMed: 19026786; DOI: 10.1016/j.molcel.2008.09.022

Experimental method

X-RAY DIFFRACTION (2.6 Å)