1FAO

STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM DAPP1/PHISH IN COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE

Summary for 1FAO

Entry DOI	10.2210/pdb1fao/pdb
Related	1FB8
Descriptor	DUAL ADAPTOR OF PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDES, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE (3 entities in total)
Functional Keywords	pleckstrin, 3-phosphoinositides, inositol tetrakisphosphate signal transduction protein, adaptor protein, signaling protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	15305.10
Authors	Ferguson, K.M.,Kavran, J.M.,Sankaran, V.G.,Fournier, E.,Isakoff, S.J.,Skolnik, E.Y.,Lemmon, M.A. (deposition date: 2000-07-13, release date: 2000-07-20, Last modification date: 2023-08-09)
Primary citation	Ferguson, K.M.,Kavran, J.M.,Sankaran, V.G.,Fournier, E.,Isakoff, S.J.,Skolnik, E.Y.,Lemmon, M.A. Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains. Mol.Cell, 6:373-384, 2000 Cited by PubMed: 10983984 DOI: 10.1016/S1097-2765(00)00037-X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation