6BNM
Crystal Structure of the P-Rex2 PH domain
Summary for 6BNM
| Entry DOI | 10.2210/pdb6bnm/pdb |
| Descriptor | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein, CHLORIDE ION (3 entities in total) |
| Functional Keywords | pleckstrin homology domain, beta sandwich, phosphatidylinositol-binding, lipid binding protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 19208.59 |
| Authors | Cash, J.N.,Sharma, P.V.,Tesmer, J.J.G. (deposition date: 2017-11-17, release date: 2018-11-21, Last modification date: 2023-10-04) |
| Primary citation | Cash, J.N.,Sharma, P.V.,Tesmer, J.J.G. Structural and biochemical characterization of the pleckstrin homology domain of the RhoGEF P-Rex2 and its regulation by PIP3. J.Struct.Biol., 1:-, 2019 Cited by DOI: 10.1016/j.yjsbx.2018.100001PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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