PDB: 871 resultsInfo pagesStatus searchChemie searchBIRD

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8TUN	S. thermodepolymerans KpsM-KpsE in Glycolipid 1 state with rigid body fitted KpsT Descriptor: (2R,5S,8S)-2,5-dihydroxy-5,10-dioxo-8-[(undecanoyloxy)methyl]-4,6,9-trioxa-5lambda~5~-phosphahenicosan-1-yl 3-deoxy-alpha-L-altro-oct-2-ulopyranosidonic acid, ABC transporter ATP-binding protein, Capsular biosynthesis protein, ... Authors: Kuklewicz, J, Zimmer, J. Deposit date: 2023-08-16 Release date: 2024-04-17 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Molecular insights into capsular polysaccharide secretion. Nature, 628, 2024
8TT3	S. thermodepolymerans KpsM-KpsE in Glycolipid 2 state with rigid body fitted KpsT Descriptor: (2R,5S,8S)-2,5-dihydroxy-5,10-dioxo-8-[(undecanoyloxy)methyl]-4,6,9-trioxa-5lambda~5~-phosphahenicosan-1-yl 3-deoxy-alpha-L-altro-oct-2-ulopyranosidonic acid, ABC transporter ATP-binding protein, Capsular biosynthesis protein, ... Authors: Kuklewicz, J, Zimmer, J. Deposit date: 2023-08-12 Release date: 2024-04-17 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Molecular insights into capsular polysaccharide secretion. Nature, 628, 2024
8TSW	S. thermodepolymerans KpsMT-KpsE Apo 1 Descriptor: ABC transporter ATP-binding protein, Capsular biosynthesis protein, Transport permease protein Authors: Kuklewicz, J, Zimmer, J. Deposit date: 2023-08-12 Release date: 2024-04-17 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Molecular insights into capsular polysaccharide secretion. Nature, 628, 2024
8TSL	S. thermodepolymerans KpsM-KpsE in Apo 2 state with rigid body fitted KpsT Descriptor: ABC transporter ATP-binding protein, Capsular biosynthesis protein, Transport permease protein Authors: Kuklewicz, J, Zimmer, J. Deposit date: 2023-08-11 Release date: 2024-04-17 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Molecular insights into capsular polysaccharide secretion. Nature, 628, 2024
8TSI	S. thermodepolymerans KpsMT-KpsE in complex with ADP:AlF4- Descriptor: ABC transporter ATP-binding protein, ADENOSINE-5'-DIPHOSPHATE, Capsular biosynthesis protein, ... Authors: Kuklewicz, J, Zimmer, J. Deposit date: 2023-08-11 Release date: 2024-04-17 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Molecular insights into capsular polysaccharide secretion. Nature, 628, 2024
8TSH	S. thermodepolymerans KpsMT(E151Q)-KpsE in complex with ATP Descriptor: ABC transporter ATP-binding protein, ADENOSINE-5'-TRIPHOSPHATE, Capsular biosynthesis protein, ... Authors: Kuklewicz, J, Zimmer, J. Deposit date: 2023-08-11 Release date: 2024-04-17 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Molecular insights into capsular polysaccharide secretion. Nature, 628, 2024
8TI2	Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ... Authors: Driggers, C.M, Shyng, S.-L. Deposit date: 2023-07-18 Release date: 2024-04-03 Method: ELECTRON MICROSCOPY (3.28 Å) Cite: Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface. Nat Commun, 15, 2024
8TI1	Cryo-EM structure of a SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in the presence of PIP2 in the open conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-sensitive inward rectifier potassium channel 11, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ... Authors: Driggers, C.M, Shyng, S.-L. Deposit date: 2023-07-18 Release date: 2024-04-03 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structure of an open K ATP channel reveals tandem PIP 2 binding sites mediating the Kir6.2 and SUR1 regulatory interface. Nat Commun, 15, 2024
8T3K	Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to ATP: BmrCD_IF-ATP2 Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ... Authors: Tang, Q, Mchaourab, H. Deposit date: 2023-06-07 Release date: 2023-11-29 Method: ELECTRON MICROSCOPY (3.33 Å) Cite: Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter. Nat Commun, 14, 2023
8T1P	Heterodimeric ABC transporter BmrCD in the occluded conformation bound to ADPVi: BmrCD_OC-ADPVi Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, ... Authors: Tang, Q, Mchaourab, H.S. Deposit date: 2023-06-02 Release date: 2023-11-15 Last modified: 2023-11-22 Method: ELECTRON MICROSCOPY (2.96 Å) Cite: Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter. Nat Commun, 14, 2023
8SZC	Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to substrate and ATP: BmrCD_IF-1HT/ATP Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Tang, Q, Mchaourab, H. Deposit date: 2023-05-29 Release date: 2023-11-15 Last modified: 2023-11-22 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter. Nat Commun, 14, 2023
8SXB	Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E2 in MSP lipid nanodisc Descriptor: (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Multidrug resistance-associated protein 4 isoform X1 Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-20 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8SXA	Inward-facing wide conformation of bovine multidrug resistance protein 4 (MRP4) in MSP lipid nanodisc Descriptor: Multidrug resistance-associated protein 4 Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-20 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8SX9	Inward-facing narrow conformation of bovine multidrug resistance protein 4 (MRP4) in MSP lipid nanodisc Descriptor: Multidrug resistance-associated protein 4 Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-20 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8SX8	Bovine multidrug resistance protein 4 (MRP4) bound to prostaglandin E1 in MSP lipid nanodisc Descriptor: 7-[(1R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid, Multidrug resistance-associated protein 4 Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-20 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8SX7	Bovine multidrug resistance protein 4 (MRP4) bound to DHEA-S in MSP lipid nanodisc Descriptor: 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, Multidrug resistance-associated protein 4 Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-20 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8SWN	Bovine multidrug resistance protein 4 (MRP4) E1202Q mutant bound to ATP in MSP lipid nanodisc Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP binding cassette subfamily C member 4, MAGNESIUM ION, ... Authors: Pourmal, S, Stroud, R.M. Deposit date: 2023-05-19 Release date: 2024-01-17 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis of prostaglandin efflux by MRP4. Nat.Struct.Mol.Biol., 31, 2024
8SQM	Cleaved Ycf1p Monomer in the IFwide-alpha conformation Descriptor: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, Metal resistance protein YCF1, Unknown peptide from Ycf1p R region Authors: Bickers, S.C, Benlekbir, S, Rubinstein, J.L, Kanelis, V. Deposit date: 2023-05-04 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure of a dimeric ABC transporter To Be Published
8SQL	Cleaved Ycf1p Monomer in the Beta Conformation Descriptor: Metal resistance protein YCF1, PHOSPHATIDYLETHANOLAMINE, Unknown peptide from Ycf1p R region Authors: Bickers, S.C, Benlekbir, S, Rubinstein, J.L, Kanelis, V. Deposit date: 2023-05-04 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Cleaved Ycf1p Monomer in the Beta Conformation To Be Published
8SQ0	Cleaved Ycf1p Dimer in the IFwide-beta conformation Descriptor: (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(pentadecanoyloxy)methyl]ethyl (12E)-hexadeca-9,12-dienoate, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, Metal resistance protein YCF1, ... Authors: Bickers, S.C, Benlekbir, S, Rubinstein, J.L, Kanelis, V. Deposit date: 2023-05-04 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structure of a dimeric ABC transporter To Be Published
8SG4	E1435Q Ycf1 mutant in dephosphorylated state Descriptor: Metal resistance protein YCF1 Authors: Khandelwal, N.K, Tomasiak, T.M. Deposit date: 2023-04-11 Release date: 2024-03-06 Method: ELECTRON MICROSCOPY (3.11 Å) Cite: E1435Q Ycf1 mutant in dephosphorylated state To Be Published
8SCB	Terminating ribosome with SRI-41315 Descriptor: (2S,4aS)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3H,4aH)-dione, 18S_rRNA, 28S_rRNA, ... Authors: Yip, M.C.J, Coelho, J.P.L, Oltion, K, Tauton, J, Shao, S. Deposit date: 2023-04-05 Release date: 2023-12-27 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Structure and consequences of eRF1 glued to the ribosomal decoding center To Be Published
8RQ4	Cryo-em structure of the rat Multidrug resistance-associated protein 2 (rMrp2) in complex with probenecid Descriptor: 4-(dipropylsulfamoyl)benzoic acid, ATP-binding cassette sub-family C member 2, CHOLESTEROL HEMISUCCINATE Authors: Mazza, T, Beis, K. Deposit date: 2024-01-17 Release date: 2024-02-14 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.45 Å) Cite: Structural basis for the modulation of MRP2 activity by phosphorylation and drugs. Nat Commun, 15, 2024
8RQ3	Cryo-em structure of the rat Multidrug resistance-associated protein 2 (rMrp2) in an autoinhibited state (nucleotide-free) Descriptor: ATP-binding cassette sub-family C member 2 Authors: Mazza, T, Beis, K. Deposit date: 2024-01-17 Release date: 2024-02-14 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.21 Å) Cite: Structural basis for the modulation of MRP2 activity by phosphorylation and drugs. Nat Commun, 15, 2024
8QOE	Inward-facing conformation of the ABC transporter BmrA Descriptor: Multidrug resistance ABC transporter ATP-binding/permease protein BmrA Authors: Di Cesare, M, Kaplan, E, Valimehr, S, Hanssen, E, Orelle, C, Jault, J.M. Deposit date: 2023-09-28 Release date: 2023-12-20 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains. J.Biol.Chem., 300, 2023

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