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6C8K
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BU of 6c8k by Molmil
RNA-activated 2-AIpG monomer complex, 30 min soaking
Descriptor: 2-amino-1-[(R)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-3-[(S)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-1H-imidazol-3-ium, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3')
Authors:Zhang, W, Szostak, J.W.
Deposit date:2018-01-24
Release date:2018-05-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.259 Å)
Cite:Crystallographic observation of nonenzymatic RNA primer extension.
Elife, 7, 2018
6C8O
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BU of 6c8o by Molmil
RNA-activated 2-AIpG monomer, 3h soaking
Descriptor: 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(hydroxy)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*G)-3')
Authors:Zhang, W, Szostak, J.W.
Deposit date:2018-01-25
Release date:2018-05-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystallographic observation of nonenzymatic RNA primer extension.
Elife, 7, 2018
6C8D
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BU of 6c8d by Molmil
RNA-dGMP complex with Mg ion
Descriptor: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3')
Authors:Zhang, W, Szostak, J.W.
Deposit date:2018-01-24
Release date:2018-05-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystallographic observation of nonenzymatic RNA primer extension.
Elife, 7, 2018
6Q8V
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BU of 6q8v by Molmil
Structure of the standard kink turn HmKt-7 variant A2bm6A.
Descriptor: RNA (5'-R(*GP*GP*CP*GP*AP*AP*GP*(6MZ)P*AP*CP*CP*GP*GP*GP*GP*AP*GP*CP*C)-3')
Authors:Huang, L, Lilley, D.M.J.
Deposit date:2018-12-16
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Effect of methylation of adenine N6on kink turn structure depends on location.
Rna Biol., 16, 2019
1ZSE
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BU of 1zse by Molmil
RNA stemloop from bacteriophage Qbeta complexed with an N87S mutant MS2 Capsid
Descriptor: Coat protein, RNA HAIRPIN
Authors:Horn, W.T, Tars, K, Grahn, E, Helgstrand, C, Baron, A.J, Lago, H, Adams, C.J, Peabody, D.S, Phillips, S.E.V, Stonehouse, N.J, Liljas, L, Stockley, P.G.
Deposit date:2005-05-24
Release date:2006-05-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis of RNA Binding Discrimination between Bacteriophages Qbeta and MS2
Structure, 14, 2006
4JRT
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BU of 4jrt by Molmil
Crystal structure of an A-form RNA duplex containing three GU base pairs
Descriptor: RNA (5'-R(P*CP*CP*UP*GP*CP*AP*CP*UP*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*UP*GP*GP*UP*GP*CP*GP*GP*G)-3')
Authors:Kondo, J, Dock-Bregeon, A.C, Willkomm, D.K, Hartmann, R.K, Westhof, E.
Deposit date:2013-03-21
Release date:2013-06-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of an A-form RNA duplex obtained by degradation of 6S RNA in a crystallization droplet
Acta Crystallogr.,Sect.F, 69, 2013
6C8J
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BU of 6c8j by Molmil
RNA-activated 2-AIpG monomer complex, 15 min soaking
Descriptor: 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(hydroxy)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3')
Authors:Zhang, W, Szostak, J.W.
Deposit date:2018-01-24
Release date:2018-05-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystallographic observation of nonenzymatic RNA primer extension.
Elife, 7, 2018
6C8N
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BU of 6c8n by Molmil
RNA-activated 2-AIpG monomer complex, 2h soaking
Descriptor: 2-amino-1-[(R)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-3-[(S)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-1H-imidazol-3-ium, 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(hydroxy)phosphoryl]guanosine, MAGNESIUM ION, ...
Authors:Zhang, W, Szostak, J.W.
Deposit date:2018-01-25
Release date:2018-05-30
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic observation of nonenzymatic RNA primer extension.
Elife, 7, 2018
280D
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BU of 280d by Molmil
THE STRUCTURE OF AN RNA DODECAMER SHOWS HOW TANDEM U-U BASE PAIRS INCREASE THE RANGE OF STABLE RNA STRUCTURES AND THE DIVERSITY OF RECOGNITION SITES
Descriptor: RNA (5'-R(*GP*GP*CP*GP*CP*UP*UP*GP*CP*GP*UP*C)-3')
Authors:Lietzke, S.E, Barnes, C.L, Kundrot, C.E.
Deposit date:1996-08-22
Release date:1996-09-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of an RNA dodecamer shows how tandem U-U base pairs increase the range of stable RNA structures and the diversity of recognition sites.
Structure, 4, 1996
6VU1
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BU of 6vu1 by Molmil
Cap3G-TAR-F1 is an RNA hairpin. The 1H-1H NOESY data was collected at 308 K in 10 mM KH2PO4 pH 7.4.
Descriptor: RNA (34-MER)
Authors:Summers, M.F, Brown, J.D.
Deposit date:2020-02-14
Release date:2020-04-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for transcriptional start site control of HIV-1 RNA fate.
Science, 368, 2020
6WY3
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BU of 6wy3 by Molmil
Crystal structure of RNA-10mer: CCGG(N4,N4-dimethyl-C)GCCGG; P212121 form
Descriptor: RNA (5'-R(*CP*CP*GP*GP*(LV2)P*GP*CP*CP*GP*G)-3')
Authors:Sekula, B, Ruszkowski, M, Mao, S, Haruehanroengra, P, Sheng, J.
Deposit date:2020-05-12
Release date:2020-09-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.647 Å)
Cite:Base pairing, structural and functional insights into N4-methylcytidine (m4C) and N4,N4-dimethylcytidine (m42C) modified RNA.
Nucleic Acids Res., 48, 2020
3NFF
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BU of 3nff by Molmil
Crystal structure of extended Dimerization module of RNA polymerase I subcomplex A49/A34.5
Descriptor: RNA polymerase I subunit A34.5, RNA polymerase I subunit A49
Authors:Geiger, S.R, Lorenzen, K, Schreieck, A, Hanecker, P, Kostrewa, D, Heck, A.J.R, Cramer, P.
Deposit date:2010-06-10
Release date:2010-09-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
6HMI
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BU of 6hmi by Molmil
Solution structure of the RNA duplex formed by the 5'-end of U1snRNA and the 5'-splice site of SMN2 exon7
Descriptor: RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
Authors:Campagne, S, Allain, F.H.
Deposit date:2018-09-12
Release date:2019-08-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis of a small molecule targeting RNA for a specific splicing correction.
Nat.Chem.Biol., 15, 2019
5UEE
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BU of 5uee by Molmil
RNA primer-template complex with guanosine dinucleotide ligand G(5')ppp(5')G
Descriptor: DIGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*GP*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3')
Authors:Zhang, W, Tam, C.P, Szostak, J.W.
Deposit date:2017-01-01
Release date:2017-07-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8SKQ
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BU of 8skq by Molmil
RNA oligonucleotide containing an alpha-(L)-threofuranosyl nucleic acid (TNA)
Descriptor: TNA-containing RNA oligonucleotide
Authors:Harp, J.M, Egli, M.
Deposit date:2023-04-20
Release date:2024-02-14
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Shorter Is Better: The alpha-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs.
J.Am.Chem.Soc., 145, 2023
4QI2
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BU of 4qi2 by Molmil
X-ray structure of the ROQ domain from murine Roquin-1 in complex with a 23-mer Tnf-CDE RNA
Descriptor: RNA (5'-R(*AP*CP*AP*UP*GP*UP*UP*UP*UP*CP*UP*GP*UP*GP*AP*AP*AP*AP*CP*GP*GP*AP*G)-3'), Roquin-1
Authors:Janowski, R, Schlundt, A, Sattler, M, Niessing, D.
Deposit date:2014-05-30
Release date:2014-07-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.
Nat.Struct.Mol.Biol., 21, 2014
1ANR
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BU of 1anr by Molmil
CIS-ACTING RNA REGULATORY ELEMENT (HIV-1 TAR), NMR, 20 STRUCTURES
Descriptor: RNA REGULATORY ELEMENT TAR
Authors:Aboul-Ela, F, Varani, G, Karn, J.
Deposit date:1996-07-06
Release date:1997-01-11
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of HIV-1 TAR RNA in the absence of ligands reveals a novel conformation of the trinucleotide bulge.
Nucleic Acids Res., 24, 1996
5V0O
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BU of 5v0o by Molmil
RNA hairpin structure containing 2-MeImpG analogue bound
Descriptor: 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (25-MER), RNA (5'-R(*GP*CP*AP*CP*CP*UP*CP*A)-3')
Authors:Zhang, W, Tam, C.P, Szostak, J.W.
Deposit date:2017-02-28
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
466D
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BU of 466d by Molmil
DISORDER AND TWIN REFINEMENT OF RNA HEPTAMER DOUBLE HELIX
Descriptor: RNA (5'-R(*GP*GP*GP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*UP*CP*C)-3'), SODIUM ION, ...
Authors:Mueller, U, Muller, Y.A, Herbst-Irmer, R, Sprinzl, M, Heinemann, U.
Deposit date:1999-04-14
Release date:1999-08-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Disorder and twin refinement of RNA heptamer double helices.
Acta Crystallogr.,Sect.D, 55, 1999
7Y2P
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BU of 7y2p by Molmil
Crystal structure of CUG repeat RNA duplex containing A-U base pair and U-U mismatches
Descriptor: RNA (5'-R(P*UP*UP*CP*UP*GP*CP*AP*GP*CP*UP*GP*AP*A)-3'), RNA (5'-R(P*UP*UP*CP*UP*GP*CP*UP*GP*CP*UP*GP*AP*A)-3')
Authors:Wang, S.C, Satange, R.B, Hou, M.H.
Deposit date:2022-06-09
Release date:2023-05-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural basis for water modulating RNA duplex formation in the CUG repeats of myotonic dystrophy type 1.
J.Biol.Chem., 299, 2023
5V9Z
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BU of 5v9z by Molmil
RNA hairpin structure containing 2-MeImpG analogue bound
Descriptor: 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (25-MER), RNA (5'-R(P*GP*CP*AP*CP*CP*UP*CP*A)-3')
Authors:Zhang, W, Szostak, J.W.
Deposit date:2017-03-24
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5VCF
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BU of 5vcf by Molmil
RNA hairpin structure containing tetraloop/receptor motif, complexed with 2-MeImpG analogue
Descriptor: 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (5'-R(*CP*UP*AP*UP*GP*CP*CP*UP*GP*CP*UP*G)-3'), RNA (5'-R(*CP*UP*GP*CP*UP*GP*GP*CP*UP*AP*AP*GP*GP*CP*CP*CP*GP*AP*AP*AP*GP*G)-3')
Authors:Zhang, W, Szostak, J.W.
Deposit date:2017-03-31
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
1NBR
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BU of 1nbr by Molmil
Iron Responsive Element RNA Hairpin, NMR, 15 Structures
Descriptor: RNA HAIRPIN
Authors:McCallum, S.A, Pardi, A.
Deposit date:2002-12-03
Release date:2003-03-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Refined Solution Structure of the Iron-responsive Element RNA Using Residual Dipolar Couplings
J.Mol.Biol., 326, 2003
5V2R
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BU of 5v2r by Molmil
Structure of a GA Rich 8x8 Nucleotide RNA Internal Loop
Descriptor: RNA (5'-R(*CP*CP*AP*GP*AP*AP*AP*CP*GP*GP*AP*UP*GP*GP*A)-3')
Authors:Kauffmann, A.D, Kennedy, S.D, Turner, D.H.
Deposit date:2017-03-06
Release date:2017-07-26
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Nuclear Magnetic Resonance Structure of an 8 8 Nucleotide RNA Internal Loop Flanked on Each Side by Three Watson-Crick Pairs and Comparison to Three-Dimensional Predictions.
Biochemistry, 56, 2017
5VCI
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BU of 5vci by Molmil
RNA hairpin structure containing tetraloop/receptor motif, complexed with 2-MeImpG analogue
Descriptor: 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (5'-R(*CP*UP*GP*CP*UP*GP*GP*CP*UP*AP*AP*GP*GP*CP*CP*CP*GP*AP*AP*AP*GP*G)-3'), RNA (5'-R(P*CP*UP*AP*UP*GP*CP*CP*UP*GP*CP*UP*G)-3')
Authors:Szostak, J.W, Zhang, W.
Deposit date:2017-03-31
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018

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