PDB: 715 resultsInfo pagesStatus searchChemie searchBIRD

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3LL8	Crystal Structure of Calcineurin in Complex with AKAP79 Peptide Descriptor: AKAP79 peptide, CALCIUM ION, Calcineurin subunit B type 1, ... Authors: Li, H, Hogan, P.G. Deposit date: 2010-01-28 Release date: 2011-01-12 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Balanced interactions of calcineurin with AKAP79 regulate Ca(2+)-calcineurin-NFAT signaling. Nat.Struct.Mol.Biol., 19, 2012
6ZV6	Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage) Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Plassart, L, Shayan, R, Plisson-Chastang, C. Deposit date: 2020-07-24 Release date: 2021-05-12 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: The final step of 40S ribosomal subunit maturation is controlled by a dual key lock. Elife, 10, 2021
6ZXH	Cryo-EM structure of a late human pre-40S ribosomal subunit - State H2 Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. Deposit date: 2020-07-29 Release date: 2020-12-16 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
6ZXG	Cryo-EM structure of a late human pre-40S ribosomal subunit - State H1 Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. Deposit date: 2020-07-29 Release date: 2020-12-02 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
6ZOJ	SARS-CoV-2-Nsp1-40S complex, composite map Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M.L, Thiel, V, Muehlemann, O, Ban, N. Deposit date: 2020-07-07 Release date: 2020-07-22 Last modified: 2021-02-10 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat.Struct.Mol.Biol., 27, 2020
5D85	Staphyloferrin B precursor biosynthetic enzyme SbnA bound to aminoacrylate intermediate Descriptor: 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, CITRATE ANION, GLYCEROL, ... Authors: Kobylarz, M.J, Grigg, J.C, Liu, Y, Lee, M.S.F, Heinrichs, D.E, Murphy, M.E.P. Deposit date: 2015-08-15 Release date: 2016-02-03 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Deciphering the Substrate Specificity of SbnA, the Enzyme Catalyzing the First Step in Staphyloferrin B Biosynthesis. Biochemistry, 55, 2016
5D86	Staphyloferrin B precursor biosynthetic enzyme SbnA Y152F variant Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, ... Authors: Kobylarz, M.J, Grigg, J.C, Liu, Y, Lee, M.S.F, Heinrichs, D.E, Murphy, M.E.P. Deposit date: 2015-08-15 Release date: 2016-02-03 Last modified: 2020-01-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Deciphering the Substrate Specificity of SbnA, the Enzyme Catalyzing the First Step in Staphyloferrin B Biosynthesis. Biochemistry, 55, 2016
5D87	Staphyloferrin B precursor biosynthetic enzyme SbnA Y152F/S185G variant Descriptor: MAGNESIUM ION, POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE, ... Authors: Kobylarz, M.J, Grigg, J.C, Liu, Y, Lee, M.S.F, Heinrichs, D.E, Murphy, M.E.P. Deposit date: 2015-08-15 Release date: 2016-02-03 Last modified: 2020-01-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Deciphering the Substrate Specificity of SbnA, the Enzyme Catalyzing the First Step in Staphyloferrin B Biosynthesis. Biochemistry, 55, 2016
7ANE	Leishmania Major mitochondrial ribosome Descriptor: 30S Ribosomal protein S17-like protein, 50S ribosomal protein L13-like protein, AKAP7_NLS domain-containing protein, ... Authors: Soufari, H, Waltz, F, Parrot, C, Bochler, A, Hashem, Y. Deposit date: 2020-10-11 Release date: 2021-06-23 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structure of the mature kinetoplastids mitoribosome and insights into its large subunit biogenesis. Proc.Natl.Acad.Sci.USA, 117, 2020
6OM7	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-18 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OLZ	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-17 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OLG	Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-16 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OLE	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-16 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6ZOL	SARS-CoV-2-Nsp1-40S complex, focused on head Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ... Authors: Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M.L, Thiel, V, Muehlemann, O, Ban, N. Deposit date: 2020-07-07 Release date: 2020-07-22 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat.Struct.Mol.Biol., 27, 2020
6OLI	Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-16 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
7K5I	SARS-COV-2 nsp1 in complex with human 40S ribosome Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Wang, L, Shi, M, Wu, H. Deposit date: 2020-09-16 Release date: 2020-10-14 Last modified: 2021-03-17 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism. Biorxiv, 2020
6OLF	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-16 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OM0	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Li, W, Cate, J.H.D. Deposit date: 2019-04-17 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
5A2Q	Structure of the HCV IRES bound to the human ribosome Descriptor: 18S RRNA, HCV IRES, MAGNESIUM ION, ... Authors: Quade, N, Leiundgut, M, Boehringer, D, Heuvel, J.v.d, Ban, N. Deposit date: 2015-05-21 Release date: 2015-07-15 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Cryo-Em Structure of Hepatitis C Virus Ires Bound to the Human Ribosome at 3.9 Angstrom Resolution Nat.Commun., 6, 2015
5AJ0	Cryo electron microscopy of actively translating human polysomes (POST state). Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Behrmann, E, Loerke, J, Budkevich, T.V, Yamamoto, K, Schmidt, A, Penczek, P.A, Vos, M.R, Burger, J, Mielke, T, Scheerer, P, Spahn, C.M.T. Deposit date: 2015-02-19 Release date: 2015-05-20 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural Snapshots of Actively Translating Human Ribosomes Cell(Cambridge,Mass.), 161, 2015
6FEC	Human cap-dependent 48S pre-initiation complex Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Schaffitzel, C, Schaffitzel, C. Deposit date: 2017-12-31 Release date: 2018-03-14 Last modified: 2018-10-03 Method: ELECTRON MICROSCOPY (6.3 Å) Cite: Structure of a human cap-dependent 48S translation pre-initiation complex. Nucleic Acids Res., 46, 2018
8JDM	Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. Deposit date: 2023-05-14 Release date: 2023-12-06 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (2.67 Å) Cite: Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
8JDL	Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. Deposit date: 2023-05-14 Release date: 2023-12-06 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (2.42 Å) Cite: Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
8JDK	Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. Deposit date: 2023-05-14 Release date: 2023-12-06 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (2.26 Å) Cite: Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
8JDJ	Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. Deposit date: 2023-05-14 Release date: 2023-12-06 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023

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