PDB: 981 resultsInfo pagesStatus searchChemie searchBIRD

---

7TDG	Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in inactivated conformation (Dataset-A) Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... Authors: Nayak, A.R, Samso, M. Deposit date: 2021-12-31 Release date: 2022-03-09 Last modified: 2022-03-16 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM. Elife, 11, 2022
7TDF	AtTPC1 D454N with 1 mM EDTA state I Descriptor: Two pore calcium channel protein 1 Authors: Dickinson, M.S, Stroud, R.M. Deposit date: 2021-12-31 Release date: 2022-02-02 Last modified: 2022-03-09 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Molecular basis of multistep voltage activation in plant two-pore channel 1. Proc.Natl.Acad.Sci.USA, 119, 2022
7TDE	AtTPC1 DDE mutant with 1 mM Ca2+ Descriptor: Two pore calcium channel protein 1 Authors: Dickinson, M.S, Stroud, R.M. Deposit date: 2021-12-31 Release date: 2022-10-12 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Molecular basis of multistep voltage activation in plant two-pore channel 1. Proc.Natl.Acad.Sci.USA, 119, 2022
7TDD	AtTPC1 D454N-EDTA state II Descriptor: Two pore calcium channel protein 1 Authors: Dickinson, M.S, Stroud, R.M. Deposit date: 2021-12-30 Release date: 2022-10-12 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Molecular basis of multistep voltage activation in plant two-pore channel 1. Proc.Natl.Acad.Sci.USA, 119, 2022
7TCP	Structure of Xenopus KCNQ1-CaM Descriptor: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1 Authors: Willegems, K, Kyriakis, E, Van Petegem, F, Eldstrom, J, Fedida, D. Deposit date: 2021-12-27 Release date: 2022-07-06 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.84 Å) Cite: Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277. Nat Commun, 13, 2022
7TCI	Structure of Xenopus KCNQ1-CaM in complex with ML277 Descriptor: (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylbenzene-1-sulfonyl)piperidine-2-carboxamide, CALCIUM ION, Calmodulin-1, ... Authors: Willegems, K, Kyriakis, E, Van Petegem, F, Eldstrom, J, Fedida, D. Deposit date: 2021-12-23 Release date: 2022-07-06 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277. Nat Commun, 13, 2022
7TBG	AtTPC1 D454N with 1 mM Ca2+ Descriptor: CALCIUM ION, SODIUM ION, Two pore calcium channel protein 1 Authors: Dickinson, M.S, Stroud, R.M. Deposit date: 2021-12-22 Release date: 2022-02-02 Last modified: 2022-03-16 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Molecular basis of multistep voltage activation in plant two-pore channel 1. Proc.Natl.Acad.Sci.USA, 119, 2022
7T6R	Cryo-EM structure of TRPV5 T709D in nanodiscs in the presence of Calmodulin Descriptor: Transient receptor potential cation channel subfamily V member 5 Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6Q	Cryo-EM structure of TRPV5 T709D with PI(4,5)P2 in nanodiscs Descriptor: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6P	Cryo-EM structure of TRPV5 T709D in nanodiscs Descriptor: Transient receptor potential cation channel subfamily V member 5 Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6O	Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 3 Descriptor: Transient receptor potential cation channel subfamily V member 5 Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6N	Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 2 Descriptor: Transient receptor potential cation channel subfamily V member 5 Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6M	Cryo-EM structure of TRPV5 in nanodiscs with PI(4,5)P2 at pH6 state 1 Descriptor: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6L	Cryo-EM structure of TRPV5 at pH5 in nanodiscs Descriptor: Transient receptor potential cation channel subfamily V member 5 Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6K	Cryo-EM structure of TRPV5 at pH6 in nanodiscs Descriptor: Transient receptor potential cation channel subfamily V member 5 Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T6J	Cryo-EM structure of TRPV5 at pH8 in nanodiscs Descriptor: Transient receptor potential cation channel subfamily V member 5 Authors: Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-14 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
7T65	Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the open state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... Authors: Iyer, K.A, Hu, Y, Murayama, T, Samso, M. Deposit date: 2021-12-13 Release date: 2022-07-20 Last modified: 2022-08-03 Method: ELECTRON MICROSCOPY (4.05 Å) Cite: Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM. Proc.Natl.Acad.Sci.USA, 119, 2022
7T64	Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the closed state Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION Authors: Iyer, K.A, Hu, Y, Murayama, T, Samso, M. Deposit date: 2021-12-13 Release date: 2022-07-20 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (4 Å) Cite: Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM. Proc.Natl.Acad.Sci.USA, 119, 2022
7T4X	AKT1 K+ channel from A. thaliana in MSP2N2 lipid nanodisc Descriptor: PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, Potassium channel AKT1 Authors: Dickinson, M.S, Pourmal, S. Deposit date: 2021-12-10 Release date: 2021-12-22 Last modified: 2022-10-26 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Symmetry Reduction in a Hyperpolarization-Activated Homotetrameric Ion Channel. Biochemistry, 61, 2022
7T3U	IP3, ATP, and Ca2+ bound type 3 IP3 receptor in the inactive state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... Authors: Schmitz, E.A, Takahashi, H, Karakas, E. Deposit date: 2021-12-08 Release date: 2022-03-23 Last modified: 2022-05-04 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
7T3T	IP3, ATP, and Ca2+ bound type 3 IP3 receptor in the active state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... Authors: Schmitz, E.A, Takahashi, H, Karakas, E. Deposit date: 2021-12-08 Release date: 2022-03-23 Last modified: 2022-05-04 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
7T3R	IP3 and ATP bound type 3 IP3 receptor in the pre-active C state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ... Authors: Schmitz, E.A, Takahashi, H, Karakas, E. Deposit date: 2021-12-08 Release date: 2022-03-23 Last modified: 2022-05-04 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
7T3Q	IP3 and ATP bound type 3 IP3 receptor in the pre-active B state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ... Authors: Schmitz, E.A, Takahashi, H, Karakas, E. Deposit date: 2021-12-08 Release date: 2022-03-23 Last modified: 2022-05-04 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
7T3P	IP3 and ATP bound type 3 IP3 receptor in the pre-active A state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ... Authors: Schmitz, E.A, Takahashi, H, Karakas, E. Deposit date: 2021-12-08 Release date: 2022-03-23 Last modified: 2022-05-04 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural basis for activation and gating of IP 3 receptors. Nat Commun, 13, 2022
7T38	Inactivated state of 2-APB and CBD-bound wildtype rat TRPV2 in nanodiscs Descriptor: Transient receptor potential cation channel subfamily V member 2 Authors: Pumroy, R.A, Protopopova, A.D, Gallo, P.N, Moiseenkova-Bell, V.Y. Deposit date: 2021-12-07 Release date: 2022-05-04 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural insights into TRPV2 activation by small molecules. Nat Commun, 13, 2022

<10111213141516171819202122232425>