7VNP
Structure of human KCNQ4-ML213 complex with PIP2
Summary for 7VNP
Entry DOI | 10.2210/pdb7vnp/pdb |
EMDB information | 32044 |
Descriptor | Potassium voltage-gated channel subfamily KQT member 4,Maltodextrin-binding protein, Calmodulin-3, [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate, ... (5 entities in total) |
Functional Keywords | kcnq4, ml213, pip2, cryo-em, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 543138.29 |
Authors | |
Primary citation | Zheng, Y.,Liu, H.,Chen, Y.,Dong, S.,Wang, F.,Wang, S.,Li, G.L.,Shu, Y.,Xu, F. Structural insights into the lipid and ligand regulation of a human neuronal KCNQ channel. Neuron, 110:237-, 2022 Cited by PubMed: 34767770DOI: 10.1016/j.neuron.2021.10.029 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.79 Å) |
Structure validation
Download full validation report