7VNP
Structure of human KCNQ4-ML213 complex with PIP2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Potassium voltage-gated channel subfamily KQT member 4,Maltodextrin-binding protein | polymer | 1049 | 116541.4 | 4 | UniProt (P56696) UniProt (A0A140NCD0) Pfam (PF00520) Pfam (PF07885) Pfam (PF03520) | Homo sapiens (Human) | KQT-like 4,Potassium channel subunit alpha KvLQT4,Voltage-gated potassium channel subunit Kv7.4 |
| 2 | B, D, F, H (B, D, F, H) | Calmodulin-3 | polymer | 149 | 16852.5 | 4 | UniProt (P0DP25) Pfam (PF13499) | Homo sapiens (Human) | |
| 3 | I, J, Q, R, T... (A, C, E, G) | [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate | non-polymer | 1047.1 | 8 | Chemie (PT5) | |||
| 4 | K, L, M, N (A) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 5 | O, P, S, V (A, C, E) | (1S,2S,4R)-N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid | non-polymer | 257.4 | 4 | Chemie (7YV) |
Sequence modifications
A, C, E, G: 2 - 650 (UniProt: P56696)
A, C, E, G: 660 - 1026 (UniProt: A0A140NCD0)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Asp -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Lys -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Asp 0 | - | expression tag |
| Lys 1 | - | expression tag |
| Leu 651 | - | linker |
| Glu 652 | - | linker |
| Val 653 | - | linker |
| Leu 654 | - | linker |
| Phe 655 | - | linker |
| Gln 656 | - | linker |
| Gly 657 | - | linker |
| Pro 658 | - | linker |
| Met 659 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Asn 1027 | - | expression tag |
| Ala 1028 | - | expression tag |
| Ala 1029 | - | expression tag |
| Ala 1030 | - | expression tag |
| Glu 1031 | - | expression tag |
| His 1032 | - | expression tag |
| His 1033 | - | expression tag |
| His 1034 | - | expression tag |
| His 1035 | - | expression tag |
| His 1036 | - | expression tag |
| His 1037 | - | expression tag |
| His 1038 | - | expression tag |
| His 1039 | - | expression tag |
| His 1040 | - | expression tag |
| His 1041 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 533575.7 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 9562.6 | |
| All* | Total formula weight | 543138.3 |
