7VNQ

Structure of human KCNQ4-ML213 complex in nanodisc

Summary for 7VNQ

• Entry DOI: 10.2210/pdb7vnq/pdb
• EMDB information: 32045
• Descriptor: Potassium voltage-gated channel subfamily KQT member 4,Maltodextrin-binding protein, Calmodulin-3, (1S,2S,4R)-N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid, ... (4 entities in total)
• Functional Keywords: kcnq4, ml213, cryo-em, nanodisc, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 534722.49

Authors

Xu, F.,Zheng, Y. (deposition date: 2021-10-11, release date: 2021-12-01, Last modification date: 2022-02-16)

• Primary citation: Zheng, Y.,Liu, H.,Chen, Y.,Dong, S.,Wang, F.,Wang, S.,Li, G.L.,Shu, Y.,Xu, F.; Structural insights into the lipid and ligand regulation of a human neuronal KCNQ channel.; Neuron, 110:237-, 2022; PubMed: 34767770; DOI: 10.1016/j.neuron.2021.10.029

Experimental method

ELECTRON MICROSCOPY (2.96 Å)