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6EXN
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BU of 6exn by Molmil
Post-catalytic P complex spliceosome with 3' splice site docked
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat: UBC4 RNA, ...
Authors:Wilkinson, M.E, Fica, S.M, Galej, W.P, Norman, C.M, Newman, A.J, Nagai, K.
Deposit date:2017-11-08
Release date:2018-01-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.
Science, 358, 2017
5WWF
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BU of 5wwf by Molmil
Crystal structure of hnRNPA2B1 in complex with RNA
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA
Authors:Wu, B.X, Su, S.C, Ma, J.B.
Deposit date:2017-01-01
Release date:2018-01-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
5WWE
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BU of 5wwe by Molmil
Crystal structure of hnRNPA2B1 in complex with RNA
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*GP*AP*CP*UP*AP*GP*A)-3')
Authors:Wu, B.X, Su, S.C, Ma, J.B.
Deposit date:2017-01-01
Release date:2018-01-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
5WWG
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BU of 5wwg by Molmil
Crystal structure of hnRNPA2B1 in complex with AAGGACUUGC
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*U)-3')
Authors:Wu, B.X, Su, S.C, Ma, J.B.
Deposit date:2017-01-01
Release date:2018-01-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
6ELZ
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BU of 6elz by Molmil
State E (TAP-Flag-Ytm1 E80A) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes
Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
Authors:Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R.
Deposit date:2017-09-30
Release date:2017-12-27
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
6EM3
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BU of 6em3 by Molmil
State A architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ...
Authors:Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R.
Deposit date:2017-10-01
Release date:2017-12-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
6EM4
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BU of 6em4 by Molmil
State B architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ...
Authors:Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R.
Deposit date:2017-10-01
Release date:2017-12-27
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
6EM5
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BU of 6em5 by Molmil
State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes
Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
Authors:Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R.
Deposit date:2017-10-01
Release date:2017-12-27
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
6EM1
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BU of 6em1 by Molmil
State C (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ...
Authors:Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R.
Deposit date:2017-10-01
Release date:2017-12-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Cell, 171, 2017
5X3Y
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BU of 5x3y by Molmil
Refined solution structure of musashi1 RBD2
Descriptor: RNA-binding protein Musashi homolog 1
Authors:Iwaoka, R, Nagata, T, Tsuda, K, Imai, T, Okano, H, Kobayashi, N, Katahira, M.
Deposit date:2017-02-09
Release date:2017-12-13
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Insight into the Recognition of r(UAG) by Musashi-1 RBD2, and Construction of a Model of Musashi-1 RBD1-2 Bound to the Minimum Target RNA
Molecules, 22, 2017
5X3Z
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BU of 5x3z by Molmil
Solution structure of musashi1 RBD2 in complex with RNA
Descriptor: RNA (5'-R(*GP*UP*AP*GP*U)-3'), RNA-binding protein Musashi homolog 1
Authors:Iwaoka, R, Nagata, T, Tsuda, K, Imai, T, Okano, H, Kobayashi, N, Katahira, M.
Deposit date:2017-02-09
Release date:2017-12-13
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Insight into the Recognition of r(UAG) by Musashi-1 RBD2, and Construction of a Model of Musashi-1 RBD1-2 Bound to the Minimum Target RNA
Molecules, 22, 2017
5OSG
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BU of 5osg by Molmil
Structure of KSRP in context of Leishmania donovani 80S
Descriptor: 18S rRNA, 40S ribosomal protein S6, RNA binding protein, ...
Authors:Brito Querido, J, Mancera-Martinez, E, Vicens, Q, Bochler, A, Chicher, J, Simonetti, A, Hashem, Y.
Deposit date:2017-08-17
Release date:2017-11-15
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The cryo-EM Structure of a Novel 40S Kinetoplastid-Specific Ribosomal Protein.
Structure, 25, 2017
5OPT
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BU of 5opt by Molmil
Structure of KSRP in context of Trypanosoma cruzi 40S
Descriptor: 18S rRNA, 40S ribosomal protein S10, putative, ...
Authors:Brito Querido, J, Mancera-Martinez, E, Vicens, Q, Bochler, A, Chicher, J, Simonetti, A, Hashem, Y.
Deposit date:2017-08-10
Release date:2017-11-15
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The cryo-EM Structure of a Novel 40S Kinetoplastid-Specific Ribosomal Protein.
Structure, 25, 2017
5OOB
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BU of 5oob by Molmil
COMPLEX OF HUMAN NUCLEAR CAP-BINDING COMPLEX WITH M7GTP AND NELF-E C-TERMINAL PEPTIDE
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Negative elongation factor E, Nuclear cap-binding protein subunit 1, ...
Authors:Cusack, S, Schulze, W.M.
Deposit date:2017-08-07
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural basis for mutually exclusive co-transcriptional nuclear cap-binding complexes with either NELF-E or ARS2.
Nat Commun, 8, 2017
5OO6
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BU of 5oo6 by Molmil
Complex of human nuclear cap-binding complex with ARS2 C-terminal peptide
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ...
Authors:Cusack, S, Schulze, W.M.
Deposit date:2017-08-06
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for mutually exclusive co-transcriptional nuclear cap-binding complexes with either NELF-E or ARS2.
Nat Commun, 8, 2017
5M8I
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BU of 5m8i by Molmil
Solution structure of CUG-BP2 RRM3 in complex with 5'-UUUAA-3' RNA
Descriptor: CUGBP Elav-like family member 2, RNA (5'-R(*UP*UP*UP*AP*A)-3')
Authors:Diarra dit Konte, N, Damberger, F.F, Allain, F.H.T.
Deposit date:2016-10-28
Release date:2017-10-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Aromatic side-chain conformational switch on the surface of the RNA Recognition Motif enables RNA discrimination.
Nat Commun, 8, 2017
5SZW
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BU of 5szw by Molmil
NMR solution structure of the RRM1 domain of the post-transcriptional regulator HuR
Descriptor: ELAV-like protein 1
Authors:Lixa, C, Mujo, A, Jendiroba, K.A, Almeida, F.C.L, Lima, L.M.T.R, Pinheiro, A.S.
Deposit date:2016-08-15
Release date:2017-09-06
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Oligomeric transition and dynamics of RNA binding by the HuR RRM1 domain in solution.
J. Biomol. NMR, 72, 2018
5KW1
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BU of 5kw1 by Molmil
Crystal Structure of the Two Tandem RRM Domains of PUF60 Bound to a Modified AdML Pre-mRNA 3' Splice Site Analogue
Descriptor: CHLORIDE ION, DNA/RNA (30-MER), Poly(U)-binding-splicing factor PUF60
Authors:Crichlow, G.V, Hsiao, H.-H, Albright, R, Lolis, E.J, Braddock, D.T.
Deposit date:2016-07-15
Release date:2017-08-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
5KVY
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BU of 5kvy by Molmil
CRYSTAL STRUCTURE OF THE TWO TANDEM RRM DOMAINS OF PUF60 BOUND TO A PORTION OF AN ADML PRE-MRNA 3' SPLICE SITE ANALOG
Descriptor: CHLORIDE ION, DNA (30-MER), Poly(U)-binding-splicing factor PUF60
Authors:Hsiao, H.-H, Crichlow, G.V, Albright, R.A, Murphy, J.W, Lolis, E.J, Braddock, D.T.
Deposit date:2016-07-15
Release date:2017-08-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
5KWQ
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BU of 5kwq by Molmil
Two Tandem RRM Domains of FBP-Interacting Repressor (FIR), also Known as PUF60
Descriptor: Poly(U)-binding-splicing factor PUF60
Authors:Crichlow, G.V, Yang, Y, Zhou, H, Lolis, E.J, Braddock, D.T.
Deposit date:2016-07-18
Release date:2017-08-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
5KW6
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BU of 5kw6 by Molmil
Two Tandem RRM Domains of PUF60 Bound to an AdML Pre-mRNA 3' Splice Site Analogue with a Modified Binding-Site Nucleic Acid Base
Descriptor: DNA (30-MER), Poly(U)-binding-splicing factor PUF60
Authors:Crichlow, G.V, Hsiao, H.-H, Albright, R, Lolis, E.J, Braddock, D.T.
Deposit date:2016-07-15
Release date:2017-08-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
5O9Z
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BU of 5o9z by Molmil
Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), ...
Authors:Bertram, K, Kastner, B.
Deposit date:2017-06-20
Release date:2017-08-16
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Cell, 170, 2017
5IFN
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BU of 5ifn by Molmil
Human PSPC1 Homodimer
Descriptor: Paraspeckle component 1
Authors:Knott, G.J, Passon, D.M, Bond, C.S.
Deposit date:2016-02-26
Release date:2017-08-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Human PSPC1 Homodimer
To Be Published
5O1T
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BU of 5o1t by Molmil
Solution structure of the RNA binding domain of Nrd1
Descriptor: Protein NRD1
Authors:Martinez-Lumbreras, S, Perez-Canadillas, J.M.
Deposit date:2017-05-19
Release date:2017-08-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition.
Nucleic Acids Res., 45, 2017
5O1Z
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BU of 5o1z by Molmil
Structure of Nrd1 RNA binding domain in complex with RNA (CGUAAA)
Descriptor: Protein NRD1, RNA (5'-R(*CP*GP*UP*AP*AP*A)-3')
Authors:Franco-Echevarria, E, Perez-Canadillas, J.M, Gonzalez, B.
Deposit date:2017-05-19
Release date:2017-08-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition.
Nucleic Acids Res., 45, 2017

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