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1A5B
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CRYO-CRYSTALLOGRAPHY OF A TRUE SUBSTRATE, INDOLE-3-GLYCEROL PHOSPHATE, BOUND TO A MUTANT (ALPHA D60N) TRYPTOPHAN SYNTHASE ALPHA2BETA2 COMPLEX REVEALS THE CORRECT ORIENTATION OF ACTIVE SITE ALPHA GLU 49
Descriptor: INDOLE-3-GLYCEROL PHOSPHATE, POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Rhee, S, Miles, E.W, Davies, D.R.
Deposit date:1998-02-12
Release date:1998-05-27
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cryo-crystallography of a true substrate, indole-3-glycerol phosphate, bound to a mutant (alphaD60N) tryptophan synthase alpha2beta2 complex reveals the correct orientation of active site alphaGlu49.
J.Biol.Chem., 273, 1998
1A5C
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FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE FROM PLASMODIUM FALCIPARUM
Descriptor: FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE
Authors:Kim, H, Certa, U, Dobeli, H, Jakob, P, Hol, W.G.J.
Deposit date:1998-02-13
Release date:1998-06-10
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of fructose-1,6-bisphosphate aldolase from the human malaria parasite Plasmodium falciparum.
Biochemistry, 37, 1998
1A5D
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GAMMAE CRYSTALLIN FROM RAT LENS
Descriptor: GAMMAE CRYSTALLIN
Authors:Norledge, B.V, Hay, R, Bateman, O.A, Slingsby, C, Driessen, H.P.C.
Deposit date:1998-02-12
Release date:1998-05-27
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Towards a molecular understanding of phase separation in the lens: a comparison of the X-ray structures of two high Tc gamma-crystallins, gammaE and gammaF, with two low Tc gamma-crystallins, gammaB and gammaD.
Exp.Eye Res., 65, 1997
1A5E
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SOLUTION NMR STRUCTURE OF TUMOR SUPPRESSOR P16INK4A, 18 STRUCTURES
Descriptor: TUMOR SUPPRESSOR P16INK4A
Authors:Byeon, I.-J.L, Li, J, Ericson, K, Selby, T.L, Tevelev, A, Kim, H.-J, O'Maille, P, Tsai, M.-D.
Deposit date:1998-02-13
Release date:1999-08-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Tumor suppressor p16INK4A: determination of solution structure and analyses of its interaction with cyclin-dependent kinase 4.
Mol.Cell, 1, 1998
1A5F
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FAB FRAGMENT OF A MONOCLONAL ANTI-E-SELECTIN ANTIBODY
Descriptor: MONOCLONAL ANTI-E-SELECTIN 7A9 ANTIBODY (HEAVY CHAIN), MONOCLONAL ANTI-E-SELECTIN 7A9 ANTIBODY (LIGHT CHAIN)
Authors:Rodriguez-Romero, A, Almog, O, Tordova, M, Randhawa, Z.
Deposit date:1998-02-16
Release date:1999-04-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Primary and tertiary structures of the Fab fragment of a monoclonal anti-E-selectin 7A9 antibody that inhibits neutrophil attachment to endothelial cells.
J.Biol.Chem., 273, 1998
1A5G
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HUMAN THROMBIN COMPLEXED WITH NOVEL SYNTHETIC PEPTIDE MIMETIC INHIBITOR AND HIRUGEN
Descriptor: (1S,7S)-7-amino-7-benzyl-N-[(1S)-4-carbamimidamido-1-{(1S)-1-hydroxy-2-oxo-2-[(2-phenylethyl)amino]ethyl}butyl]-8-oxohexahydro-1H-pyrazolo[1,2-a]pyridazine-1-carboxamide, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ...
Authors:St Charles, R, Tulinsky, A, Kahn, M.
Deposit date:1998-02-16
Release date:1998-05-27
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Bound structures of novel P3-P1' beta-strand mimetic inhibitors of thrombin.
J.Med.Chem., 42, 1999
1A5H
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CATALYTIC DOMAIN OF HUMAN TWO-CHAIN TISSUE PLASMINOGEN ACTIVATOR COMPLEX OF A BIS-BENZAMIDINE
Descriptor: 2,7-BIS-(4-AMIDINOBENZYLIDENE)-CYCLOHEPTAN-1-ONE, TISSUE PLASMINOGEN ACTIVATOR
Authors:Renatus, M, Bode, W, Stubbs, M.T.
Deposit date:1998-02-17
Release date:1999-04-20
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural mapping of the active site specificity determinants of human tissue-type plasminogen activator. Implications for the design of low molecular weight substrates and inhibitors.
J.Biol.Chem., 272, 1997
1A5I
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CATALYTIC DOMAIN OF VAMPIRE BAT (DESMODUS ROTUNDUS) SALIVA PLASMINOGEN ACTIVATOR IN COMPLEX WITH EGR-CMK (GLU-GLY-ARG CHLOROMETHYL KETONE)
Descriptor: L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide, PLASMINOGEN ACTIVATOR
Authors:Renatus, M, Stubbs, M.T, Bode, W.
Deposit date:1998-02-17
Release date:1999-03-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Catalytic domain structure of vampire bat plasminogen activator: a molecular paradigm for proteolysis without activation cleavage.
Biochemistry, 36, 1997
1A5J
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CHICKEN B-MYB DNA BINDING DOMAIN, REPEAT 2 AND REPEAT3, NMR, 32 STRUCTURES
Descriptor: B-MYB
Authors:Mcintosh, P.B, Carr, M.D, Wollborn, U, Frenkiel, T.A, Feeney, J, Mccormick, J.E, Klempnauer, K.H.
Deposit date:1998-02-16
Release date:1998-07-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the B-Myb DNA-binding domain: a possible role for conformational instability of the protein in DNA binding and control of gene expression.
Biochemistry, 37, 1998
1A5K
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K217E VARIANT OF KLEBSIELLA AEROGENES UREASE
Descriptor: UREASE (ALPHA SUBUNIT), UREASE (BETA SUBUNIT), UREASE (GAMMA SUBUNIT)
Authors:Pearson, M.A, Schaller, R.A, Michel, L.O, Karplus, P.A, Hausinger, R.P.
Deposit date:1998-02-17
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand.
Biochemistry, 37, 1998
1A5L
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K217C VARIANT OF KLEBSIELLA AEROGENES UREASE
Descriptor: UREASE (ALPHA SUBUNIT), UREASE (BETA SUBUNIT), UREASE (GAMMA SUBUNIT)
Authors:Pearson, M.A, Schaller, R.A, Michel, L.O, Karplus, P.A, Hausinger, R.P.
Deposit date:1998-02-17
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand.
Biochemistry, 37, 1998
1A5M
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K217A VARIANT OF KLEBSIELLA AEROGENES UREASE
Descriptor: UREASE (ALPHA SUBUNIT), UREASE (BETA SUBUNIT), UREASE (GAMMA SUBUNIT)
Authors:Pearson, M.A, Schaller, R.A, Michel, L.O, Karplus, P.A, Hausinger, R.P.
Deposit date:1998-02-17
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand.
Biochemistry, 37, 1998
1A5N
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K217A VARIANT OF KLEBSIELLA AEROGENES UREASE, CHEMICALLY RESCUED BY FORMATE AND NICKEL
Descriptor: FORMIC ACID, NICKEL (II) ION, UREASE (ALPHA SUBUNIT), ...
Authors:Pearson, M.A, Schaller, R.A, Michel, L.O, Karplus, P.A, Hausinger, R.P.
Deposit date:1998-02-17
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand.
Biochemistry, 37, 1998
1A5O
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K217C VARIANT OF KLEBSIELLA AEROGENES UREASE, CHEMICALLY RESCUED BY FORMATE AND NICKEL
Descriptor: FORMIC ACID, NICKEL (II) ION, UREASE (ALPHA SUBUNIT), ...
Authors:Pearson, M.A, Schaller, R.A, Michel, L.O, Karplus, P.A, Hausinger, R.P.
Deposit date:1998-02-17
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand.
Biochemistry, 37, 1998
1A5P
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C[40,95]A VARIANT OF BOVINE PANCREATIC RIBONUCLEASE A
Descriptor: RIBONUCLEASE A, SULFATE ION
Authors:Pearson, M.A, Karplus, P.A, Dodge, R.W, Laity, J.H, Scheraga, H.A.
Deposit date:1998-02-17
Release date:1998-05-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of two mutants that have implications for the folding of bovine pancreatic ribonuclease A.
Protein Sci., 7, 1998
1A5Q
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P93A VARIANT OF BOVINE PANCREATIC RIBONUCLEASE A
Descriptor: RIBONUCLEASE A, SULFATE ION
Authors:Pearson, M.A, Karplus, P.A, Dodge, R.W, Laity, J.H, Scheraga, H.A.
Deposit date:1998-02-17
Release date:1998-05-27
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of two mutants that have implications for the folding of bovine pancreatic ribonuclease A.
Protein Sci., 7, 1998
1A5R
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STRUCTURE DETERMINATION OF THE SMALL UBIQUITIN-RELATED MODIFIER SUMO-1, NMR, 10 STRUCTURES
Descriptor: SUMO-1
Authors:Bayer, P, Arndt, A, Metzger, S, Mahajan, R, Melchior, F, Jaenicke, R, Becker, J.
Deposit date:1998-02-18
Release date:1998-10-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure determination of the small ubiquitin-related modifier SUMO-1.
J.Mol.Biol., 280, 1998
1A5S
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CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH 5-FLUOROINDOLE PROPANOL PHOSPHATE AND L-SER BOUND AS AMINO ACRYLATE TO THE BETA SITE
Descriptor: 5-FLUOROINDOLE PROPANOL PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, SERINE, ...
Authors:Schneider, T.R, Gerhardt, E, Lee, M, Liang, P.-H, Anderson, K.S, Schlichting, I.
Deposit date:1998-02-17
Release date:1999-03-30
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Loop closure and intersubunit communication in tryptophan synthase.
Biochemistry, 37, 1998
1A5T
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CRYSTAL STRUCTURE OF THE DELTA PRIME SUBUNIT OF THE CLAMP-LOADER COMPLEX OF ESCHERICHIA COLI DNA POLYMERASE III
Descriptor: DELTA PRIME, ZINC ION
Authors:Guenther, B, Onrust, R, Sali, A, O'Donnell, M, Kuriyan, J.
Deposit date:1998-02-18
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III.
Cell(Cambridge,Mass.), 91, 1997
1A5U
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PYRUVATE KINASE COMPLEX WITH BIS MG-ATP-NA-OXALATE
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, OXALATE ION, ...
Authors:Larsen, T.M, Benning, M.M, Rayment, I, Reed, G.H.
Deposit date:1998-02-18
Release date:1999-03-02
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of the bis(Mg2+)-ATP-oxalate complex of the rabbit muscle pyruvate kinase at 2.1 A resolution: ATP binding over a barrel.
Biochemistry, 37, 1998
1A5V
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ASV INTEGRASE CORE DOMAIN WITH HIV-1 INTEGRASE INHIBITOR Y3 AND MN CATION
Descriptor: 4-ACETYLAMINO-5-HYDROXYNAPHTHALENE-2,7-DISULFONIC ACID, INTEGRASE, MANGANESE (II) ION
Authors:Lubkowski, J, Yang, F, Alexandratos, J, Wlodawer, A.
Deposit date:1998-02-18
Release date:1998-05-27
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor.
Proc.Natl.Acad.Sci.USA, 95, 1998
1A5W
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ASV INTEGRASE CORE DOMAIN WITH HIV-1 INTEGRASE INHIBITOR Y3
Descriptor: 4-ACETYLAMINO-5-HYDROXYNAPHTHALENE-2,7-DISULFONIC ACID, INTEGRASE
Authors:Lubkowski, J, Yang, F, Alexandratos, J, Wlodawer, A.
Deposit date:1998-02-18
Release date:1998-05-27
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor.
Proc.Natl.Acad.Sci.USA, 95, 1998
1A5X
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ASV INTEGRASE CORE DOMAIN WITH HIV-1 INTEGRASE INHIBITOR Y3
Descriptor: 4-ACETYLAMINO-5-HYDROXYNAPHTHALENE-2,7-DISULFONIC ACID, INTEGRASE
Authors:Lubkowski, J, Yang, F, Alexandratos, J, Wlodawer, A.
Deposit date:1998-02-18
Release date:1998-05-27
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor.
Proc.Natl.Acad.Sci.USA, 95, 1998
1A5Y
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PROTEIN TYROSINE PHOSPHATASE 1B CYSTEINYL-PHOSPHATE INTERMEDIATE
Descriptor: PROTEIN TYROSINE PHOSPHATASE 1B
Authors:Pannifer, A.D.P, Flint, A.J, Tonks, N.K, Barford, D.
Deposit date:1998-02-19
Release date:1998-06-17
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Visualization of the cysteinyl-phosphate intermediate of a protein-tyrosine phosphatase by x-ray crystallography.
J.Biol.Chem., 273, 1998
1A5Z
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LACTATE DEHYDROGENASE FROM THERMOTOGA MARITIMA (TMLDH)
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, CADMIUM ION, L-LACTATE DEHYDROGENASE, ...
Authors:Auerbach, G, Ostendorp, R, Prade, L, Korndoerfer, I, Dams, T, Huber, R, Jaenicke, R.
Deposit date:1998-02-18
Release date:1999-03-23
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Lactate dehydrogenase from the hyperthermophilic bacterium thermotoga maritima: the crystal structure at 2.1 A resolution reveals strategies for intrinsic protein stabilization.
Structure, 6, 1998

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