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7RU0
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BU of 7ru0 by Molmil
SthK R120A Open State 1
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK
Authors:Gao, X, Nimigean, C, Schmidpeter, P.
Deposit date:2021-08-16
Release date:2022-11-23
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel.
Nat Commun, 13, 2022
6PB4
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BU of 6pb4 by Molmil
The E. coli class-II CAP-dependent transcription activation complex with de novo RNA transcript at the state 2
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Liu, B, Shi, W.
Deposit date:2019-06-13
Release date:2020-03-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.35 Å)
Cite:Visualization of two architectures in class-II CAP-dependent transcription activation
Plos Biol., 18, 2020
6QCZ
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BU of 6qcz by Molmil
MloK1 model from single particle analysis of 2D crystals, class 3 (intermediate extended conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
5I2D
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BU of 5i2d by Molmil
Crystal structure of T. thermophilus TTHB099 class II transcription activation complex: TAP-RPo
Descriptor: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Feng, Y, Zhang, Y, Ebright, R.H.
Deposit date:2016-02-08
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.405 Å)
Cite:Structural basis of transcription activation.
Science, 352, 2016
8H3V
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BU of 8h3v by Molmil
Cryo-EM structure of the full transcription activation complex NtcA-NtcB-TAC
Descriptor: DNA (125-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Han, S.J, Jiang, Y.L, You, L.L, Shen, L.Q, Wu, X.X, Yang, F, Kong, W.W, Chen, Z.P, Zhang, Y, Zhou, C.Z.
Deposit date:2022-10-09
Release date:2023-10-04
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:DNA looping mediates cooperative transcription activation.
Nat.Struct.Mol.Biol., 31, 2024
6QD0
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BU of 6qd0 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 4 (compact/open conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6EO1
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BU of 6eo1 by Molmil
The electron crystallography structure of the cAMP-bound potassium channel MloK1 (PCO-refined)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Kowal, J, Biyani, N, Chami, M, Scherer, S, Rzepiela, A, Baumgartner, P, Upadhyay, V, Nimigean, C, Stahlberg, H.
Deposit date:2017-10-08
Release date:2017-12-27
Last modified:2024-05-15
Method:ELECTRON CRYSTALLOGRAPHY (4.5 Å)
Cite:High-Resolution Cryoelectron Microscopy Structure of the Cyclic Nucleotide-Modulated Potassium Channel MloK1 in a Lipid Bilayer.
Structure, 26, 2018
6PB5
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BU of 6pb5 by Molmil
The E. coli class-II CAP-dependent transcription activation complex at the state 1 architecture
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Liu, B, Shi, W.
Deposit date:2019-06-13
Release date:2020-03-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.52 Å)
Cite:Visualization of two architectures in class-II CAP-dependent transcription activation
Plos Biol., 18, 2020
6QCY
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BU of 6qcy by Molmil
MloK1 model from single particle analysis of 2D crystals, class 2 (intermediate conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6BYS
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BU of 6bys by Molmil
Structures of the PKA RI alpha holoenzyme with the FLHCC driver J-PKAc alpha or native PRKAc alpha
Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type I-alpha regulatory subunit
Authors:Cao, B, Lu, T.W, Martinez Fiesco, J.A, Tomasini, M, Fan, L, Simon, S.M, Taylor, S.S, Zhang, P.
Deposit date:2017-12-21
Release date:2019-04-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.75 Å)
Cite:Structures of the PKA RI alpha Holoenzyme with the FLHCC Driver J-PKAc alpha or Wild-Type PKAc alpha.
Structure, 27, 2019
6QD2
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BU of 6qd2 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 6 (intermediate compact conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
8EP0
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BU of 8ep0 by Molmil
Eag Kv channel with voltage sensor in the intermediate conformation
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
Authors:Mandala, V.S, MacKinnon, R.
Deposit date:2022-10-04
Release date:2022-11-16
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
6QD3
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BU of 6qd3 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 7 (intermediate conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
5CIZ
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BU of 5ciz by Molmil
E. coli RNA polymerase alpha subunit CTD in complex with CAP and DNA: A(5)-tract binding site for alpha CTD
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA (5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*AP*GP*GP*CP*AP*AP*AP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*TP*TP*TP*GP*CP*CP*TP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3'), ...
Authors:Napoli, A.A, Lawson, C.L.
Deposit date:2015-07-13
Release date:2016-06-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (5.0098 Å)
Cite:The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element
Biochemistry, 2020
6IAX
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BU of 6iax by Molmil
MloK1 model from single particle analysis of 2D crystals, class 1 (extended conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-11-27
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6QD1
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BU of 6qd1 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 5 (intermediate compact conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
8EP1
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BU of 8ep1 by Molmil
Eag Kv channel with voltage sensor in the down conformation
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
Authors:Mandala, V.S, MacKinnon, R.
Deposit date:2022-10-04
Release date:2022-11-16
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
6QD4
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BU of 6qd4 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 8 (intermediate conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6WJG
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BU of 6wjg by Molmil
PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma
Descriptor: DnaJ homolog subfamily B member 1, cAMP-dependent protein kinase catalytic subunit alpha fusion, cAMP-dependent protein kinase type II-beta regulatory subunit
Authors:Lu, T.-W, Aoto, P.C, Weng, J.-H, Nielsen, C, Cash, J.N, Hall, J, Zhang, P, Simon, S.M, Cianfrocco, M.A, Taylor, S.S.
Deposit date:2020-04-13
Release date:2020-12-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.
Plos Biol., 18, 2020
6VY0
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BU of 6vy0 by Molmil
SthK P300A cyclic nucleotide-gated potassium channel in a putative active state, in complex with cAMP
Descriptor: SthK
Authors:Schmidpeter, P.A.M, Rheinberger, J, Nimigean, C.M.
Deposit date:2020-02-25
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.68 Å)
Cite:Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel.
Nat Commun, 11, 2020
4CHW
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BU of 4chw by Molmil
The electron crystallography structure of the cAMP-free potassium channel MloK1
Descriptor: CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION
Authors:Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H.
Deposit date:2013-12-04
Release date:2014-01-15
Last modified:2024-05-08
Method:ELECTRON CRYSTALLOGRAPHY (7 Å)
Cite:Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.
Nat Commun, 5, 2014
4CHV
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BU of 4chv by Molmil
The electron crystallography structure of the cAMP-bound potassium channel MloK1
Descriptor: CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION
Authors:Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H.
Deposit date:2013-12-04
Release date:2014-01-15
Last modified:2024-05-08
Method:ELECTRON CRYSTALLOGRAPHY (7 Å)
Cite:Ligand-Induced Structural Changes in the Cyclic Nucleotide-Modulated Potassium Channel Mlok1
Nat.Commun., 5, 2014
6WJF
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BU of 6wjf by Molmil
PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma
Descriptor: DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha fusion, cAMP-dependent protein kinase type II-beta regulatory subunit
Authors:Lu, T.-W, Aoto, P.C, Weng, J.-H, Nielsen, C, Cash, J.N, Hall, J, Zhang, P, Simon, S.M, Cianfrocco, M.A, Taylor, S.S.
Deposit date:2020-04-13
Release date:2020-12-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.
Plos Biol., 18, 2020
3IYD
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BU of 3iyd by Molmil
Three-dimensional EM structure of an intact activator-dependent transcription initiation complex
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DNA (98-MER), ...
Authors:Hudson, B.P, Quispe, J, Lara, S, Kim, Y, Berman, H, Arnold, E, Ebright, R.H, Lawson, C.L.
Deposit date:2009-08-01
Release date:2009-11-10
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (19.799999 Å)
Cite:Three-dimensional EM structure of an intact activator-dependent transcription initiation complex
Proc.Natl.Acad.Sci.USA, 106, 2009
3J4Q
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BU of 3j4q by Molmil
Pseudo-atomic model of the AKAP18-PKA complex in a bent conformation derived from electron microscopy
Descriptor: A-kinase anchor protein 18, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-alpha regulatory subunit
Authors:Reichow, S.L, Gonen, T.
Deposit date:2013-09-25
Release date:2013-11-13
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation.
Elife, 2, 2013

223532

PDB entries from 2024-08-07

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