5CIZ

E. coli RNA polymerase alpha subunit CTD in complex with CAP and DNA: A(5)-tract binding site for alpha CTD

Summary for 5CIZ

• Entry DOI: 10.2210/pdb5ciz/pdb
• Related: 3N4M
• Descriptor: cAMP-activated global transcriptional regulator CRP, DNA-directed RNA polymerase subunit alpha, DNA (5'-D(*CP*TP*TP*TP*TP*TP*GP*CP*CP*TP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3'), ... (5 entities in total)
• Functional Keywords: protein-protein interactions, protein-dna interactions, gene regulation-dna complex, knock out, gene regulation/dna
• Biological source: Escherichia coli (strain K12); More
• Total number of polymer chains: 4
• Total formula weight: 46735.04

Authors

Napoli, A.A.,Lawson, C.L. (deposition date: 2015-07-13, release date: 2016-06-29, Last modification date: 2023-09-27)

• Primary citation: Lara-Gonzalez, S.,Machado, A.C.D.,Rao, S.,Napoli, A.A.,Birktoft, J.,Di Felice, R.,Rohs, R.,Lawson, C.L.; The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element; Biochemistry, 2020; DOI: 10.1021/acs.biochem.0c00571

Experimental method

X-RAY DIFFRACTION (5.0098 Å)