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1FJG
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STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTICS STREPTOMYCIN, SPECTINOMYCIN, AND PAROMOMYCIN
Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Wimberly, B.T, Morgan-Warren, R.J, Ramakrishnan, V.
Deposit date:2000-08-08
Release date:2000-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
Nature, 407, 2000
1Y60
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Structure of the tetrahydromethanopterin dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1 with bound 5,10-methylene tetrahydromethanopterin
Descriptor: 5,10-DIMETHYLENE TETRAHYDROMETHANOPTERIN, Formaldehyde-activating enzyme fae
Authors:Acharya, P, Goenrich, M, Hagemeier, C.H, Demmer, U, Vorholt, J.A, Thauer, R.K, Ermler, U.
Deposit date:2004-12-03
Release date:2005-01-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:How an enzyme binds the C1-carrier tetrahydromethanopterin: Structure of the tetrahydromethanopterin dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1
J.Biol.Chem., 280, 2005
2Y0M
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN DOSAGE COMPENSATION FACTORS MSL1 AND MOF
Descriptor: ACETYL COENZYME *A, MALE-SPECIFIC LETHAL 1 HOMOLOG, PROBABLE HISTONE ACETYLTRANSFERASE MYST1, ...
Authors:Kadlec, J, Hallacli, E, Lipp, M, Holz, H, Sanchez Weatherby, J, Cusack, S, Akhtar, A.
Deposit date:2010-12-03
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for Mof and Msl3 Recruitment Into the Dosage Compensation Complex by Msl1.
Nat.Struct.Mol.Biol., 18, 2011
2Y0N
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BU of 2y0n by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN DOSAGE COMPENSATION FACTORS MSL1 AND MSL3
Descriptor: MALE-SPECIFIC LETHAL 1 HOMOLOG, MALE-SPECIFIC LETHAL 3 HOMOLOG
Authors:Kadlec, J, Hallacli, E, Lipp, M, Holz, H, Sanchez Weatherby, J, Cusack, S, Akhtar, A.
Deposit date:2010-12-04
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for Mof and Msl3 Recruitment Into the Dosage Compensation Complex by Msl1.
Nat.Struct.Mol.Biol., 18, 2011
3EQG
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BU of 3eqg by Molmil
X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a ternary complex with PD, ADP AND MG2P
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Dual specificity mitogen-activated protein kinase kinase 1, ...
Authors:Fischmann, T.O.
Deposit date:2008-09-30
Release date:2009-02-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors.
Biochemistry, 48, 2009
2OD1
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BU of 2od1 by Molmil
Solution structure of the MYND domain from human AML1-ETO
Descriptor: Protein CBFA2T1, ZINC ION
Authors:Liu, Y.Z, Chen, W, Gaudet, J, Cheney, M.D, Roudaia, L, Cierpicki, T, Klet, R.C, Hartman, K, Laue, T.M, Speck, N.A, Bushweller, J.H.
Deposit date:2006-12-21
Release date:2007-06-19
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.
Cancer Cell, 11, 2007
8SON
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BU of 8son by Molmil
Crystal structure of macrophage migration inhibitory factor in complex with N-[3-(Trifluoromethyl)phenyl]-3-(2-chloroanilino)-2-cyano-3-thioxopropanamide
Descriptor: (2R)-3-[(2-chlorophenyl)amino]-2-cyano-3-thioxo-N-[3-(trifluoromethyl)phenyl]propanamide, GLYCEROL, Macrophage migration inhibitory factor, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2023-04-28
Release date:2024-05-22
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Crystal structure of the macrophage migration inhibitory factor in complex with N-[3-(Trifluoromethyl)phenyl]-3-(2-chloroanilino)-2-cyano-3-thioxopropanamide
To Be Published
1FSI
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BU of 1fsi by Molmil
CRYSTAL STRUCTURE OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE OF APPR>P FROM ARABIDOPSIS THALIANA
Descriptor: CYCLIC PHOSPHODIESTERASE, SULFATE ION
Authors:Hofmann, A, Zdanov, A, Genschik, P, Filipowicz, W, Ruvinov, S, Wlodawer, A.
Deposit date:2000-09-10
Release date:2000-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and mechanism of activity of the cyclic phosphodiesterase of Appr>p, a product of the tRNA splicing reaction.
EMBO J., 19, 2000
2CKW
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BU of 2ckw by Molmil
The 2.3 A resolution structure of the Sapporo virus RNA dependant RNA polymerase.
Descriptor: RNA-DIRECTED RNA POLYMERASE
Authors:Fullerton, S.W.B, Tucker, P.A, Rohayem, J, Coutard, B, Gebhardt, J, Gorbalenya, A, Canard, B.
Deposit date:2006-04-24
Release date:2006-11-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Functional Characterization of Sapovirus RNA-Dependent RNA Polymerase.
J.Virol., 81, 2007
1Y73
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HIV-1 Dis(Mal) Duplex Pt-Soaked
Descriptor: 5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', MAGNESIUM ION, PLATINUM (IV) ION
Authors:Ennifar, E, Walter, P, Dumas, P.
Deposit date:2004-12-08
Release date:2004-12-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A crystallographic study of the binding of 13 metal ions to two related RNA duplexes
Nucleic Acids Res., 31, 2003
3UFE
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Structure of transcriptional antiterminator (BGLG-family) at 1.5 A resolution
Descriptor: CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ...
Authors:Grosse, C, Himmel, S, Becker, S, Sheldrick, G.M, Uson, I.
Deposit date:2011-11-01
Release date:2012-02-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of transcriptional antiterminator (BGLG-family) at 1.5 A resolution
To be Published
2CR7
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BU of 2cr7 by Molmil
Solution structure of the first PAH domain of the mouse transcriptional repressor SIN3B
Descriptor: Paired amphipathic helix protein Sin3b
Authors:Nagashima, K, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-20
Release date:2005-11-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the first PAH domain of the mouse transcriptional repressor SIN3B
to be published
3UEH
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BU of 3ueh by Molmil
Crystal structure of human Survivin H80A mutant
Descriptor: 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 5, DI(HYDROXYETHYL)ETHER, ...
Authors:Niedzialkowska, E, Porebski, P.J, Wang, F, Higgins, J.M, Stukenberg, P.T, Minor, W.
Deposit date:2011-10-30
Release date:2012-03-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres.
Mol Biol Cell, 23, 2012
2NYI
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Crystal Structure of an Unknown Protein from Galdieria sulphuraria
Descriptor: unknown protein
Authors:Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, McCoy, J.G, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2006-11-20
Release date:2006-12-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of tandem ACT domain-containing protein ACTP from Galdieria sulphuraria.
Proteins, 80, 2012
1Z3L
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BU of 1z3l by Molmil
X-Ray Crystal Structure of a Mutant Ribonuclease S (F8Anb)
Descriptor: Ribonuclease pancreatic, S-Peptide, S-Protein, ...
Authors:Das, M, Vasudeva Rao, B, Ghosh, S, Varadarajan, R.
Deposit date:2005-03-14
Release date:2005-03-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Attempts to delineate the relative contributions of changes in hydrophobicity and packing to changes in stability of ribonuclease S mutants.
Biochemistry, 44, 2005
2ZU6
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BU of 2zu6 by Molmil
crystal structure of the eIF4A-PDCD4 complex
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, Eukaryotic initiation factor 4A-I, ...
Authors:Cho, Y, Chang, J.H, Sohn, S.Y.
Deposit date:2008-10-13
Release date:2009-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the eIF4A-PDCD4 complex
Proc.Natl.Acad.Sci.Usa, 106, 2009
3UIG
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BU of 3uig by Molmil
crystal structure of human Survivin in complex with T3 phosphorylated H3(1-15) peptide
Descriptor: Baculoviral IAP repeat-containing protein 5, T3 phosphorylated H3(1-15) peptide, ZINC ION
Authors:Du, J, Patel, D.J.
Deposit date:2011-11-04
Release date:2012-02-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin.
Structure, 20, 2012
3UIP
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BU of 3uip by Molmil
Complex between human RanGAP1-SUMO1, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II
Descriptor: E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ...
Authors:Gareau, J.R, Reverter, D, Lima, C.D.
Deposit date:2011-11-05
Release date:2011-12-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.293 Å)
Cite:Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2.
J.Biol.Chem., 287, 2012
1Z9D
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BU of 1z9d by Molmil
Crystal structure of a putative uridylate kinase (UMP-kinase) from Streptococcus pyogenes
Descriptor: SULFATE ION, uridylate kinase
Authors:Rajashankar, K.R, Kniewel, R, Lee, K, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-04-01
Release date:2005-04-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a putative uridylate kinase (UMP-kinase) from Streptococcus pyogenes
To be Published
3UR0
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BU of 3ur0 by Molmil
Crystal structures of murine norovirus RNA-dependent RNA polymerase in complex with Suramin
Descriptor: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID, RNA-dependent RNA polymerase, SULFATE ION
Authors:Milani, M, Mastrangelo, E, Bolognesi, M.
Deposit date:2011-11-21
Release date:2012-05-02
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases.
J.Mol.Biol., 419, 2012
2O9B
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BU of 2o9b by Molmil
Crystal Structure of Bacteriophytochrome chromophore binding domain
Descriptor: 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome
Authors:Wagner, J.R, Brunzelle, J.S, Vierstra, R.D, Forest, K.T.
Deposit date:2006-12-13
Release date:2007-03-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:High resolution structure of deinococcus bacteriophytochrome yields new insights into phytochrome architecture and evolution.
J.Biol.Chem., 282, 2007
7JVU
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BU of 7jvu by Molmil
Crystal structure of human histone deacetylase 8 (HDAC8) I45T mutation complexed with SAHA
Descriptor: 1,2-ETHANEDIOL, Histone deacetylase 8, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ...
Authors:Osko, J.D, Christianson, D.W, Decroos, C, Porter, N.J, Lee, M.
Deposit date:2020-08-24
Release date:2020-12-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.5004766 Å)
Cite:Structural analysis of histone deacetylase 8 mutants associated with Cornelia de Lange Syndrome spectrum disorders.
J.Struct.Biol., 213, 2020
1ZAI
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BU of 1zai by Molmil
Fructose-1,6-bisphosphate Schiff base intermediate in FBP aldolase from rabbit muscle
Descriptor: 1,6-FRUCTOSE DIPHOSPHATE (LINEAR FORM), Fructose-bisphosphate aldolase A
Authors:St-Jean, M, Lafrance-Vanasse, J, Liotard, B, Sygusch, J.
Deposit date:2005-04-06
Release date:2005-05-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:High Resolution Reaction Intermediates of Rabbit Muscle Fructose-1,6-bisphosphate Aldolase: substrate cleavage and induced fit.
J.Biol.Chem., 280, 2005
1ZCH
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BU of 1zch by Molmil
Structure of the hypothetical oxidoreductase YcnD from Bacillus subtilis
Descriptor: CALCIUM ION, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
Authors:Morokutti, A, Lyskowski, A, Sollner, S, Pointner, E, Fitzpatrick, T.B, Kratky, C, Gruber, K, Macheroux, P.
Deposit date:2005-04-12
Release date:2005-11-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure and Function of YcnD from Bacillus subtilis, a Flavin-Containing Oxidoreductase(,).
Biochemistry, 44, 2005
7NC4
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Crystal structure of human carbonic anhydrase VII (hCA VII) in complex with a 4-(4-aroylpiperazine-1-carbonyl)benzenesulfonamide derivative.
Descriptor: 4-[4-(2-chlorophenyl)carbonylpiperazin-1-yl]carbonylbenzenesulfonamide, Carbonic anhydrase 7, GLYCEROL, ...
Authors:Di Fiore, A, De Simone, G.
Deposit date:2021-01-28
Release date:2021-07-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Design, synthesis and biochemical evaluation of novel carbonic anhydrase inhibitors triggered by structural knowledge on hCA VII.
Bioorg.Med.Chem., 44, 2021

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