2NYI

Crystal Structure of an Unknown Protein from Galdieria sulphuraria

Summary for 2NYI

• Entry DOI: 10.2210/pdb2nyi/pdb
• Descriptor: unknown protein (2 entities in total)
• Functional Keywords: protein structure initiative, psi, center for eukaryotic structural genomics, cesg, structural genomics, unknown function
• Biological source: Galdieria sulphuraria
• Total number of polymer chains: 2
• Total formula weight: 42424.08

Authors

Bitto, E.,Wesenberg, G.E.,Phillips Jr., G.N.,McCoy, J.G.,Bingman, C.A.,Center for Eukaryotic Structural Genomics (CESG) (deposition date: 2006-11-20, release date: 2006-12-12, Last modification date: 2024-11-13)

Primary citation

Bitto, E.,Kim, D.J.,Bingman, C.A.,Kim, H.J.,Han, B.W.,Phillips, G.N.
Crystal structure of tandem ACT domain-containing protein ACTP from Galdieria sulphuraria.
Proteins, 80:2105-2109, 2012

PubMed Abstract: The ACT domain is a structurally conserved small molecule binding domain which is mostly involved in amino acid and purine metabolism. Here, we report the crystal structure of a tandem ACT domain-containing protein (ACTP) from Galdieria sulphuraria. The two ACTP monomers in the asymmetric unit form a dimer with a non-crystallographic twofold axis in a domain-swapped manner, showing a horseshoe-like structure with a central crevice. This structure contributes to expand our knowledge on the structural diversity of ACT domain-containing proteins.

PubMed: 22528523
DOI: 10.1002/prot.24101

Experimental method

X-RAY DIFFRACTION (1.8 Å)