2C53
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![BU of 2c53 by Molmil](/molmil-images/mine/2c53) | A comparative study of uracil DNA glycosylases from human and herpes simplex virus type 1 | Descriptor: | 2'-DEOXYURIDINE, GLYCEROL, URACIL DNA GLYCOSYLASE | Authors: | Krusong, K, Carpenter, E.P, Bellmy, S.R.W, Savva, R, Baldwin, G.S. | Deposit date: | 2005-10-25 | Release date: | 2005-11-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Comparative Study of Uracil-DNA Glycosylases from Human and Herpes Simplex Virus Type 1. J.Biol.Chem., 281, 2006
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2C54
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![BU of 2c54 by Molmil](/molmil-images/mine/2c54) | gdp-mannose-3', 5' -epimerase (arabidopsis thaliana),k178r, with gdp-beta-l-gulose and gdp-4-keto-beta-l-gulose bound in active site. | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FORMIC ACID, GDP-MANNOSE-3', ... | Authors: | Major, L.L, Wolucka, B.A, Naismith, J.H. | Deposit date: | 2005-10-25 | Release date: | 2005-11-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure and function of GDP-mannose-3',5'-epimerase: an enzyme which performs three chemical reactions at the same active site. J. Am. Chem. Soc., 127, 2005
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2C55
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![BU of 2c55 by Molmil](/molmil-images/mine/2c55) | Solution Structure of the Human Immunodeficiency Virus Type 1 p6 Protein | Descriptor: | PROTEIN P6 | Authors: | Fossen, T, Wray, V, Bruns, K, Rachmat, J, Henklein, P, Tessmer, U, Maczurek, A, Klinger, P, Schubert, U. | Deposit date: | 2005-10-25 | Release date: | 2005-11-02 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Human Immunodeficiency Virus Type 1 P6 Protein. J.Biol.Chem., 280, 2005
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2C56
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![BU of 2c56 by Molmil](/molmil-images/mine/2c56) | A comparative study of uracil DNA glycosylases from human and herpes simplex virus type 1 | Descriptor: | URACIL DNA GLYCOSYLASE, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | Authors: | Krusong, K, Carpenter, E.P, Bellamy, S.R.W, Savva, R, Baldwin, G.S. | Deposit date: | 2005-10-26 | Release date: | 2005-11-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A Comparative Study of Uracil-DNA Glycosylases from Human and Herpes Simplex Virus Type 1. J.Biol.Chem., 281, 2006
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2C57
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![BU of 2c57 by Molmil](/molmil-images/mine/2c57) | H.pylori type II dehydroquinase in complex with FA1 | Descriptor: | 2,3 -ANHYDRO-QUINIC ACID, 3-DEHYDROQUINATE DEHYDRATASE | Authors: | Robinson, D.A, Lapthorn, A.J. | Deposit date: | 2005-10-26 | Release date: | 2006-02-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal Structures of Helicobacter Pylori Type II Dehydroquinase Inhibitor Complexes: New Directions for Inhibitor Design. J.Med.Chem., 49, 2006
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2C58
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![BU of 2c58 by Molmil](/molmil-images/mine/2c58) | Torpedo californica acetylcholinesterase in complex with 20mM acetylthiocholine | Descriptor: | 2-(TRIMETHYLAMMONIUM)ETHYL THIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... | Authors: | Colletier, J.P, Fournier, D, Greenblatt, H.M, Sussman, J.L, Zaccai, G, Silman, I, Weik, M. | Deposit date: | 2005-10-26 | Release date: | 2006-06-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Insights Into Substrate Traffic and Inhibition in Acetylcholinesterase. Embo J., 25, 2006
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2C59
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![BU of 2c59 by Molmil](/molmil-images/mine/2c59) | gdp-mannose-3', 5' -epimerase (arabidopsis thaliana), with gdp-alpha-d-mannose and gdp-beta-l-galactose bound in the active site. | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, GDP-MANNOSE-3', ... | Authors: | Major, L.L, Wolucka, B.A, Naismith, J.H. | Deposit date: | 2005-10-26 | Release date: | 2005-11-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and Function of Gdp-Mannose-3',5'-Epimerase: An Enzyme which Performs Three Chemical Reactions at the Same Active Site. J.Am.Chem.Soc., 127, 2005
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2C5A
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![BU of 2c5a by Molmil](/molmil-images/mine/2c5a) | GDP-mannose-3', 5' -epimerase (Arabidopsis thaliana),Y174F, with GDP-beta-L-galactose bound in the active site | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, GDP-MANNOSE-3', ... | Authors: | Major, L.L, Wolucka, B.A, Naismith, J.H. | Deposit date: | 2005-10-26 | Release date: | 2005-11-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure and Function of Gdp-Mannose-3',5'-Epimerase: An Enzyme which Performs Three Chemical Reactions at the Same Active Site. J.Am.Chem.Soc., 127, 2005
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2C5B
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![BU of 2c5b by Molmil](/molmil-images/mine/2c5b) | X-ray crystal structure of 5'-fluorodeoxyadenosine synthase from Streptomyces cattleya complexed with 2'deoxy-5'deoxy-fluoroadenosine. | Descriptor: | 5'-FLUORO-2',5'-DIDEOXYADENOSINE, 5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE, METHIONINE | Authors: | McEwan, A.R, Deng, H, McGlinchey, R.P, Robinson, D.A, O'Hagan, D, Naismith, J.H, Spencer, J. | Deposit date: | 2005-10-26 | Release date: | 2007-02-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Substrate Specificity in Enzymatic Fluorination. The Fluorinase from Streptomyces Cattleya Accepts 2'-Deoxyadenosine Substrates. Org.Biomol.Chem., 4, 2006
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2C5C
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![BU of 2c5c by Molmil](/molmil-images/mine/2c5c) | |
2C5D
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![BU of 2c5d by Molmil](/molmil-images/mine/2c5d) | Structure of a minimal Gas6-Axl complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN 6 PRECURSOR, ... | Authors: | Sasaki, T, Knyazev, P.G, Clout, N.J, Cheburkin, Y, Goehring, W, Ullrich, A, Timpl, R, Hohenester, E. | Deposit date: | 2005-10-26 | Release date: | 2005-12-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural Basis for Gas6-Axl Signalling. Embo J., 25, 2006
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2C5E
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![BU of 2c5e by Molmil](/molmil-images/mine/2c5e) | gdp-mannose-3', 5' -epimerase (arabidopsis thaliana), k217a, with gdp-alpha-d-mannose bound in the active site. | Descriptor: | FORMIC ACID, GDP-MANNOSE-3', 5'-EPIMERASE, ... | Authors: | Major, L.L, Wolucka, B.A, Naismith, J.H. | Deposit date: | 2005-10-26 | Release date: | 2005-11-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure and Function of Gdp-Mannose-3',5'-Epimerase: An Enzyme which Performs Three Chemical Reactions at the Same Active Site. J.Am.Chem.Soc., 127, 2005
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2C5F
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![BU of 2c5f by Molmil](/molmil-images/mine/2c5f) | Torpedo californica acetylcholinesterase in complex with a non hydrolysable substrate analogue, 4-oxo-N,N,N-trimethylpentanaminium | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4-DIHYDROXY-N,N,N-TRIMETHYLPENTAN-1-AMINIUM, ACETYLCHOLINESTERASE, ... | Authors: | Colletier, J.P, Fournier, D, Greenblatt, H.M, Sussman, J.L, Zaccai, G, Silman, I, Weik, M. | Deposit date: | 2005-10-27 | Release date: | 2006-06-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Insights Into Substrate Traffic and Inhibition in Acetylcholinesterase. Embo J., 25, 2006
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2C5G
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![BU of 2c5g by Molmil](/molmil-images/mine/2c5g) | Torpedo californica acetylcholinesterase in complex with 20mM thiocholine | Descriptor: | 2-(TRIMETHYLAMMONIUM)ETHYL THIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... | Authors: | Colletier, J.P, Fournier, D, Greenblatt, H.M, Sussman, J.L, Zaccai, G, Silman, I, Weik, M. | Deposit date: | 2005-10-27 | Release date: | 2006-06-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural Insights Into Substrate Traffic and Inhibition in Acetylcholinesterase. Embo J., 25, 2006
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2C5H
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![BU of 2c5h by Molmil](/molmil-images/mine/2c5h) | X-ray crystal structure of 5'-fluorodeoxyadenosine synthase from Streptomyces cattleya complexed with 2'deoxy-adenosine | Descriptor: | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, 5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE, CHLORIDE ION, ... | Authors: | McEwan, A.R, Deng, H, McGlinchey, R.P, Robinson, D.R, O'Hagan, D, Naismith, J.H, Spencer, J. | Deposit date: | 2005-10-27 | Release date: | 2006-10-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Substrates and Inhibitors of the Fluorinase from Streptomyces Cattleya To be Published
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2C5I
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![BU of 2c5i by Molmil](/molmil-images/mine/2c5i) | N-terminal domain of tlg1 complexed with N-terminus of vps51 in distorted conformation | Descriptor: | SULFATE ION, T-SNARE AFFECTING A LATE GOLGI COMPARTMENT PROTEIN 1, VACUOLAR PROTEIN SORTING PROTEIN 51 | Authors: | Fridmann-Sirkis, Y, Kent, H.M, Lewis, M.J, Evans, P.R, Pelham, H.R.B. | Deposit date: | 2005-10-27 | Release date: | 2006-01-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Analysis of the Interaction between the Snare Tlg1 and Vps51. Traffic, 7, 2006
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2C5J
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![BU of 2c5j by Molmil](/molmil-images/mine/2c5j) | N-terminal domain of tlg1, domain-swapped dimer | Descriptor: | T-SNARE AFFECTING A LATE GOLGI COMPARTMENT PROTEIN 1 | Authors: | Fridmann-Sirkis, Y, Kent, H.M, Lewis, M.J, Evans, P.R, Pelham, H.R.B. | Deposit date: | 2005-10-27 | Release date: | 2006-01-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Analysis of the Interaction between the Snare Tlg1 and Vps51. Traffic, 7, 2006
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2C5K
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![BU of 2c5k by Molmil](/molmil-images/mine/2c5k) | N-terminal domain of tlg1 complexed with N-terminus of vps51 | Descriptor: | SULFATE ION, T-SNARE AFFECTING A LATE GOLGI COMPARTMENT PROTEIN 1, VACUOLAR PROTEIN SORTING PROTEIN 51 | Authors: | Fridmann-Sirkis, Y, Kent, H.M, Lewis, M.J, Evans, P.R, Pelham, H.R.B. | Deposit date: | 2005-10-27 | Release date: | 2006-01-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Analysis of the Interaction between the Snare Tlg1 and Vps51. Traffic, 7, 2006
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2C5L
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![BU of 2c5l by Molmil](/molmil-images/mine/2c5l) | Structure of PLC epsilon Ras association domain with hRas | Descriptor: | GLYCEROL, GTPASE HRAS, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Roe, S.M, Bunney, T.D, Katan, M, Pearl, L.H. | Deposit date: | 2005-10-27 | Release date: | 2006-02-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Mechanistic Insights Into Ras Association Domains of Phospholipase C Epsilon Mol.Cell, 21, 2006
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2C5N
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![BU of 2c5n by Molmil](/molmil-images/mine/2c5n) | Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design | Descriptor: | CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE | Authors: | Kontopidis, G, McInnes, C, Pandalaneni, S.R, McNae, I, Gibson, D, Mezna, M, Thomas, M, Wood, G, Wang, S, Walkinshaw, M.D, Fischer, P.M. | Deposit date: | 2005-10-30 | Release date: | 2006-03-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design. Chem.Biol., 13, 2006
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2C5O
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![BU of 2c5o by Molmil](/molmil-images/mine/2c5o) | Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design | Descriptor: | 4-(2,4-DIMETHYL-1,3-THIAZOL-5-YL)PYRIMIDIN-2-AMINE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2 | Authors: | Kontopidis, G, McInnes, C, Pandalaneni, S.R, McNae, I, Gibson, D, Mezna, M, Thomas, M, Wood, G, Wang, S, Walkinshaw, M.D, Fischer, P.M. | Deposit date: | 2005-10-30 | Release date: | 2006-03-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design. Chem.Biol., 13, 2006
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2C5Q
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![BU of 2c5q by Molmil](/molmil-images/mine/2c5q) | Crystal structure of yeast YER010Cp | Descriptor: | 1,2-ETHANEDIOL, RRAA-LIKE PROTEIN YER010C | Authors: | Leulliot, N, Quevillon-Cheruel, S, Graille, M, Schiltz, M, Blondeau, K, Janin, J, van Tilbeurgh, H. | Deposit date: | 2005-10-31 | Release date: | 2005-11-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of Yeast Yer010Cp, a Knotable Member of the Rraa Protein Family. Protein Sci., 14, 2005
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2C5R
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![BU of 2c5r by Molmil](/molmil-images/mine/2c5r) | The structure of phage phi29 replication organizer protein p16.7 in complex with double stranded DNA | Descriptor: | 5'-D(*CP*CP*GP*GP*TP*GP*GP*AP)-3', 5'-D(*TP*CP*CP*AP*CP*CP*GP*GP)-3', EARLY PROTEIN P16.7 | Authors: | Albert, A, Jimenez, M, Munoz-Espin, D, Asensio, J.L, Hermoso, J.A, Salas, M, Meijer, W.J.J. | Deposit date: | 2005-10-31 | Release date: | 2005-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural Basis for Membrane Anchorage of Viral Phi 29 DNA During Replication. J.Biol.Chem., 280, 2005
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2C5S
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![BU of 2c5s by Molmil](/molmil-images/mine/2c5s) | Crystal structure of Bacillus anthracis ThiI, a tRNA-modifying enzyme containing the predicted RNA-binding THUMP domain | Descriptor: | ADENOSINE MONOPHOSPHATE, PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII | Authors: | Waterman, D.G, Ortiz-Lombardia, M, Fogg, M.J, Koonin, E.V, Antson, A.A. | Deposit date: | 2005-11-01 | Release date: | 2005-11-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of Bacillus anthracis ThiI, a tRNA-modifying enzyme containing the predicted RNA-binding THUMP domain. J.Mol.Biol., 356, 2006
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2C5U
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![BU of 2c5u by Molmil](/molmil-images/mine/2c5u) | T4 RNA Ligase (Rnl1) Crystal Structure | Descriptor: | CALCIUM ION, CHLORIDE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... | Authors: | El Omari, K, Ren, J, Bird, L.E, Bona, M.K, Klarmann, G, LeGrice, S.F.J, Stammers, D.K. | Deposit date: | 2005-11-01 | Release date: | 2005-11-04 | Last modified: | 2012-09-12 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Molecular Architecture and Ligand Recognition Determinants for T4 RNA Ligase J.Biol.Chem., 281, 2006
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