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2C54

gdp-mannose-3', 5' -epimerase (arabidopsis thaliana),k178r, with gdp-beta-l-gulose and gdp-4-keto-beta-l-gulose bound in active site.

Summary for 2C54
Entry DOI10.2210/pdb2c54/pdb
Related2C59 2C5A 2C5E
DescriptorGDP-MANNOSE-3', 5'-EPIMERASE, GUANOSINE 5'-DIPHOSPHATE-BETA-L-GULOSE, GUANOSINE 5'-DIPHOSPHATE-4-KETO-BETA-L-GULOSE, ... (7 entities in total)
Functional Keywords3' 5'-epimerase, short chain dehydratase/reductase, gdp-mannose, gdp-gulose, gdp-galactose, keto intermediate, vitamin c, sdr, isomerase, ascorbate biosynthesis, nad
Biological sourceArabidopsis thaliana (MOUSE-EAR CRESS)
Total number of polymer chains2
Total formula weight90754.16
Authors
Major, L.L.,Wolucka, B.A.,Naismith, J.H. (deposition date: 2005-10-25, release date: 2005-11-14, Last modification date: 2019-01-30)
Primary citationMajor, L.L.,Wolucka, B.A.,Naismith, J.H.
Structure and function of GDP-mannose-3',5'-epimerase: an enzyme which performs three chemical reactions at the same active site.
J. Am. Chem. Soc., 127:18309-18320, 2005
Cited by
PubMed: 16366586
DOI: 10.1021/ja056490i
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

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