2C54

gdp-mannose-3', 5' -epimerase (arabidopsis thaliana),k178r, with gdp-beta-l-gulose and gdp-4-keto-beta-l-gulose bound in active site.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	GDP-MANNOSE-3', 5'-EPIMERASE	polymer	379	42971.6	2	UniProt (Q93VR3) Pfam (PF01370) In PDB	Arabidopsis thaliana (MOUSE-EAR CRESS)	GDP-MAN 3,5-EPIMERASE
2	A, B	GUANOSINE 5'-DIPHOSPHATE-BETA-L-GULOSE	non-polymer		605.3	2	Chemie (GKE)
3	A, B	GUANOSINE 5'-DIPHOSPHATE-4-KETO-BETA-L-GULOSE	non-polymer		603.3	2	Chemie (GKD)
4	A, B	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
5	B, A	FORMIC ACID	non-polymer		46.0	18	Chemie (FMT)
6	A	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	1	Chemie (EPE)
7		water	water		18.0	944	Chemie (HOH)

Sequence modifications

A, B: -1 - 0 (PDB: 2C54)
A, B: 1 - 377 (UniProt: Q93VR3)

PDB	External Database	Details
Arg 178	Lys 178	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	85943.2
Non-Polymers*	Number of molecules	25
	Total formula weight	4810.9
All*	Total formula weight	90754.2

*Water molecules are not included.