4KZ4
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![BU of 4kz4 by Molmil](/molmil-images/mine/4kz4) | Crystal structure of AmpC beta-lactamase in complex with fragment 60 (2-[(propylsulfonyl)amino]benzoic acid) | Descriptor: | 2-[(propylsulfonyl)amino]benzoic acid, Beta-lactamase, PHOSPHATE ION | Authors: | Eidam, O, Barelier, S, Fish, I, Shoichet, B.K. | Deposit date: | 2013-05-29 | Release date: | 2014-05-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Increasing chemical space coverage by combining empirical and computational fragment screens. Acs Chem.Biol., 9, 2014
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4KZ8
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![BU of 4kz8 by Molmil](/molmil-images/mine/4kz8) | Crystal structure of AmpC beta-lactamase in complex with fragment 20 (1,3-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione) | Descriptor: | 1,3-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione, Beta-lactamase, PHOSPHATE ION | Authors: | Eidam, O, Barelier, S, Fish, I, Shoichet, B.K. | Deposit date: | 2013-05-29 | Release date: | 2014-05-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.282 Å) | Cite: | Increasing chemical space coverage by combining empirical and computational fragment screens. Acs Chem.Biol., 9, 2014
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4JXV
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![BU of 4jxv by Molmil](/molmil-images/mine/4jxv) | |
4KZ5
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![BU of 4kz5 by Molmil](/molmil-images/mine/4kz5) | Crystal structure of AmpC beta-lactamase in complex with fragment 5 (N-{[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}glycine) | Descriptor: | Beta-lactamase, N-{[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}glycine, PHOSPHATE ION | Authors: | Eidam, O, Barelier, S, Fish, I, Shoichet, B.K. | Deposit date: | 2013-05-29 | Release date: | 2014-05-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Increasing chemical space coverage by combining empirical and computational fragment screens. Acs Chem.Biol., 9, 2014
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4LCL
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![BU of 4lcl by Molmil](/molmil-images/mine/4lcl) | Simvastatin Synthase (LOVD), from Aspergillus Terreus, LovD6 mutant (simh6208) | Descriptor: | ISOPROPYL ALCOHOL, Transesterase | Authors: | Gao, X, Sawaya, M.R, Yeates, T.O, Tang, Y. | Deposit date: | 2013-06-21 | Release date: | 2014-04-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The role of distant mutations and allosteric regulation on LovD active site dynamics. Nat.Chem.Biol., 10, 2014
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4KEN
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![BU of 4ken by Molmil](/molmil-images/mine/4ken) | Crystal Structure of AmpC beta-lactamase N152G Mutant in Complex with Cefoxitin | Descriptor: | (2R)-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase, PHOSPHATE ION | Authors: | Docter, B.E, Baggett, V.L, Powers, R.A, Wallar, B.J. | Deposit date: | 2013-04-25 | Release date: | 2014-10-29 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Complexed structures of AmpC beta-lactamase To be Published
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4KG5
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![BU of 4kg5 by Molmil](/molmil-images/mine/4kg5) | Crystal Structure of AmpC beta-lactamase N152G Mutant in Complex with Cefotaxime | Descriptor: | Beta-lactamase, CEFOTAXIME, C3' cleaved, ... | Authors: | Docter, B.E, Baggett, V.L, Powers, R.A, Wallar, B.J. | Deposit date: | 2013-04-28 | Release date: | 2014-10-29 | Last modified: | 2018-09-19 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Complexed structures of AmpC beta-lactamase To be Published
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4N9L
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![BU of 4n9l by Molmil](/molmil-images/mine/4n9l) | crystal structure of beta-lactamse PenP_E166S in complex with meropenem | Descriptor: | (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Beta-lactamase | Authors: | Pan, X, Wong, W, Zhao, Y. | Deposit date: | 2013-10-21 | Release date: | 2014-09-10 | Last modified: | 2022-02-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation Biochemistry, 53, 2014
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4KG2
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![BU of 4kg2 by Molmil](/molmil-images/mine/4kg2) | Crystal Structure of AmpC beta-lactamase from E. coli in Complex with Cefotaxime | Descriptor: | Beta-lactamase, CEFOTAXIME, C3' cleaved, ... | Authors: | Docter, B.E, Baggett, V.L, Powers, R.A, Wallar, B.J. | Deposit date: | 2013-04-28 | Release date: | 2014-10-29 | Last modified: | 2018-09-19 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Complexed structures of AmpC beta-lactamase To be Published
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4N9K
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![BU of 4n9k by Molmil](/molmil-images/mine/4n9k) | crystal structure of beta-lactamse PenP_E166S in complex with cephaloridine | Descriptor: | 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase | Authors: | Pan, X, Wong, W, Zhao, Y. | Deposit date: | 2013-10-21 | Release date: | 2014-09-10 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation Biochemistry, 53, 2014
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4N92
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![BU of 4n92 by Molmil](/molmil-images/mine/4n92) | Crystal structure of beta-lactamse PenP_E166S | Descriptor: | Beta-lactamase | Authors: | Pan, X, Wong, W, Zhao, Y. | Deposit date: | 2013-10-19 | Release date: | 2014-09-10 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation Biochemistry, 53, 2014
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4NET
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![BU of 4net by Molmil](/molmil-images/mine/4net) | Crystal structure of ADC-1 beta-lactamase | Descriptor: | AmpC, GLYCEROL, NITRATE ION | Authors: | Bhattacharya, M, Toth, M, Antunes, N.T, Smith, C.A, Vakulenko, S.B. | Deposit date: | 2013-10-30 | Release date: | 2014-03-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structure of the extended-spectrum class C beta-lactamase ADC-1 from Acinetobacter baumannii. Acta Crystallogr.,Sect.D, 70, 2014
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4NK3
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![BU of 4nk3 by Molmil](/molmil-images/mine/4nk3) | Amp-c beta-lactamase (pseudomonas aeruginosa) in complex with mk-7655 | Descriptor: | (2S,5R)-1-formyl-N-(piperidin-4-yl)-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase | Authors: | Scapin, G, Lu, J, Fitzgerald, P.M.D, Sharma, N. | Deposit date: | 2013-11-12 | Release date: | 2014-02-19 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of MK-7655, a beta-lactamase inhibitor for combination with Primaxin(). Bioorg.Med.Chem.Lett., 24, 2014
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4KG6
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![BU of 4kg6 by Molmil](/molmil-images/mine/4kg6) | |
4N1H
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![BU of 4n1h by Molmil](/molmil-images/mine/4n1h) | Structure of a single-domain camelid antibody fragment cAb-F11N in complex with the BlaP beta-lactamase from Bacillus licheniformis | Descriptor: | Beta-lactamase, Camelid heavy-chain antibody variable fragment cAb-F11N | Authors: | Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | Deposit date: | 2013-10-04 | Release date: | 2014-10-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments To be Published
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5E2G
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![BU of 5e2g by Molmil](/molmil-images/mine/5e2g) | Crystal Structure of D-alanine Carboxypeptidase AmpC from Burkholderia cenocepacia | Descriptor: | ACETIC ACID, Beta-lactamase, THIOCYANATE ION | Authors: | Kim, Y, Joachimiak, G, Endres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-10-01 | Release date: | 2015-10-14 | Method: | X-RAY DIFFRACTION (1.651 Å) | Cite: | Crystal Structure of D-alanine Carboxypeptidase AmpC from Burkholderia cenocepacia To Be Published
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5EVL
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![BU of 5evl by Molmil](/molmil-images/mine/5evl) | Crystal Structure of Beta-Lactamase/D-Alanine Carboxypeptidase from Chromobacterium violaceum | Descriptor: | Beta-lactamase, CHLORIDE ION, GLYCEROL, ... | Authors: | Kim, Y, Hatzos-Skintges, C, Endres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-11-19 | Release date: | 2015-12-02 | Last modified: | 2019-11-27 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Crystal Structure of Beta-Lactamase/D-Alanine Carboxypeptidase from Chromobacterium violaceum To Be Published
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5F1F
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![BU of 5f1f by Molmil](/molmil-images/mine/5f1f) | Crystal structure of CMY-10 adenylylated by acetyl-AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Beta-lactamase, CADMIUM ION | Authors: | An, Y.J, Kim, M.K, Na, J.H, Cha, S.S. | Deposit date: | 2015-11-30 | Release date: | 2016-12-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.548 Å) | Cite: | Structural and mechanistic insights into the inhibition of class C beta-lactamases through the adenylylation of the nucleophilic serine. J.Antimicrob.Chemother., 72, 2017
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5F1G
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![BU of 5f1g by Molmil](/molmil-images/mine/5f1g) | Crystal structure of AmpC BER adenylylated in the cytoplasm | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Beta-lactamase, ... | Authors: | An, Y.J, Kim, M.K, Na, J.H, Cha, S.S. | Deposit date: | 2015-11-30 | Release date: | 2016-12-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structural and mechanistic insights into the inhibition of class C beta-lactamases through the adenylylation of the nucleophilic serine. J.Antimicrob.Chemother., 72, 2017
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5EVI
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![BU of 5evi by Molmil](/molmil-images/mine/5evi) | Crystal Structure of Beta-Lactamase/D-Alanine Carboxypeptidase from Pseudomonas syringae | Descriptor: | 1,2-ETHANEDIOL, Beta-Lactamase/D-Alanine Carboxypeptidase, SULFATE ION | Authors: | Kim, Y, Hatzos-Skintges, C, Endres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-11-19 | Release date: | 2016-01-13 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Beta-Lactamase/D-Alanine Carboxypeptidase from Pseudomonas syringae To Be Published
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5GMX
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![BU of 5gmx by Molmil](/molmil-images/mine/5gmx) | Crystal structure of a family VIII carboxylesterase | Descriptor: | Carboxylesterase, phenylmethanesulfonic acid | Authors: | An, Y.J, Cha, S.S. | Deposit date: | 2016-07-18 | Release date: | 2017-07-26 | Last modified: | 2019-02-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of EstSRT1, a family VIII carboxylesterase displaying hydrolytic activity toward oxyimino cephalosporins Biochem. Biophys. Res. Commun., 478, 2016
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5GHY
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![BU of 5ghy by Molmil](/molmil-images/mine/5ghy) | |
5E2H
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![BU of 5e2h by Molmil](/molmil-images/mine/5e2h) | Crystal Structure of D-alanine Carboxypeptidase AmpC from Mycobacterium smegmatis | Descriptor: | Beta-lactamase, CHLORIDE ION, GLYCEROL | Authors: | Kim, Y, Hatzos-Skintges, C, Endres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-10-01 | Release date: | 2015-10-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of D-alanine Carboxypeptidase AmpC from Mycobacterium smegmatis To Be Published
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5GHZ
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![BU of 5ghz by Molmil](/molmil-images/mine/5ghz) | |
5GKV
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![BU of 5gkv by Molmil](/molmil-images/mine/5gkv) | Crystal Structure of a Novel Penicillin-Binding Protein (PBP) Homolog from Caulobacter crescentus | Descriptor: | Esterase A | Authors: | Ngo, T.D, Ryu, B.H, Kim, B.Y, Yoo, W.K, Lee, E.J, Lee, S.J, Kim, T.D, Kim, K.K. | Deposit date: | 2016-07-07 | Release date: | 2017-07-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Biochemical and Structural Analysis of a Novel Penicillin-Binding Protein (PBP) Homolog from Caulobacter crescentus To Be Published
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