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7ZSC
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BU of 7zsc by Molmil
Crystal structure of the heterodimeric human C-P4H-II with truncated alpha subunit (C-P4H-II delta281)
Descriptor: Prolyl 4-hydroxylase subunit alpha-2, Protein disulfide-isomerase, SULFATE ION
Authors:Lebedev, A, Koski, M.K, Wierenga, R.K, Murthy, A.V, Sulu, R.
Deposit date:2022-05-06
Release date:2022-11-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H alpha 2 beta 2 tetramer.
J.Biol.Chem., 298, 2022
8J07
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BU of 8j07 by Molmil
96nm repeat of human respiratory doublet microtubule and associated axonemal complexes
Descriptor: ACTA2, Axonemal dynein light intermediate polypeptide 1, Calaxin, ...
Authors:Gui, M, Brown, A.
Deposit date:2023-04-09
Release date:2023-07-26
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Axonemal structures reveal mechanoregulatory and disease mechanisms.
Nature, 618, 2023
6GDG
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BU of 6gdg by Molmil
Cryo-EM structure of the adenosine A2A receptor bound to a miniGs heterotrimer
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Garcia-Nafria, J, Lee, Y.
Deposit date:2018-04-23
Release date:2018-05-16
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.11 Å)
Cite:Cryo-EM structure of the adenosine A2Areceptor coupled to an engineered heterotrimeric G protein.
Elife, 7, 2018
8GZU
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BU of 8gzu by Molmil
Cryo-EM structure of Tetrahymena thermophila respiratory Megacomplex MC (IV2+I+III2+II)2
Descriptor: 2 iron, 2 sulfur cluster-binding protein, 2-oxoglutarate/malate carrier protein, ...
Authors:Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L.
Deposit date:2022-09-27
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (4.18 Å)
Cite:Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
Nat Commun, 14, 2023
6N7W
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BU of 6n7w by Molmil
Structure of bacteriophage T7 leading-strand DNA polymerase (D5A/E7A)/Trx in complex with a DNA fork and incoming dTTP (from multiple lead complexes)
Descriptor: DNA (25-MER), DNA (77-MER), DNA-directed DNA polymerase, ...
Authors:Gao, Y, Fox, T, Val, N, Yang, W.
Deposit date:2018-11-28
Release date:2019-03-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
7K5B
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BU of 7k5b by Molmil
Structure of outer-arm dynein bound to microtubule doublet in microtubule binding state 2 (MTBS-2)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
Authors:Rao, Q, Zhang, K.
Deposit date:2020-09-16
Release date:2021-09-29
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Nat.Struct.Mol.Biol., 28, 2021
6TML
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BU of 6tml by Molmil
Cryo-EM structure of Toxoplasma gondii mitochondrial ATP synthase hexamer, composite model
Descriptor: ATP synthase subunit alpha, ATP synthase subunit beta, ATP synthase subunit delta, ...
Authors:Muhleip, A, Kock Flygaard, R, Amunts, A.
Deposit date:2019-12-04
Release date:2020-12-16
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria.
Nat Commun, 12, 2021
5IKN
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BU of 5ikn by Molmil
Crystal Structure of the T7 Replisome in the Absence of DNA
Descriptor: DNA primase/helicase, DNA-directed DNA polymerase, Thioredoxin-1
Authors:Wallen, J.R, Ellenberger, T.
Deposit date:2016-03-03
Release date:2016-12-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.802 Å)
Cite:Hybrid Methods Reveal Multiple Flexibly Linked DNA Polymerases within the Bacteriophage T7 Replisome.
Structure, 25, 2017
6ENY
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BU of 6eny by Molmil
Structure of the human PLC editing module
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Calreticulin, ...
Authors:Trowitzsch, S, Januliene, D, Blees, A, Moeller, A, Tampe, R.
Deposit date:2017-10-07
Release date:2017-11-29
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structure of the human MHC-I peptide-loading complex.
Nature, 551, 2017
7MOQ
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BU of 7moq by Molmil
The structure of the Tetrahymena thermophila outer dynein arm on doublet microtubule
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Docking complex 1 protein, ...
Authors:Kubo, S, Yang, S.K, Ichikawa, M, Bui, K.H.
Deposit date:2021-05-03
Release date:2021-07-14
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Remodeling and activation mechanisms of outer arm dyneins revealed by cryo-EM.
Embo Rep., 22, 2021
7KEK
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BU of 7kek by Molmil
Structure of the free outer-arm dynein in pre-parallel state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein alpha heavy chain, ...
Authors:Rao, Q, Zhang, K.
Deposit date:2020-10-11
Release date:2021-09-29
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Nat.Struct.Mol.Biol., 28, 2021
6ZYW
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BU of 6zyw by Molmil
Outer Dynein Arm-Shulin complex - overall structure (Tetrahymena thermophila)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
Authors:Mali, G.R, Abid Ali, F, Lau, C.K, Carter, A.P.
Deposit date:2020-08-03
Release date:2021-01-20
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (8.78 Å)
Cite:Shulin packages axonemal outer dynein arms for ciliary targeting.
Science, 371, 2021
8BX8
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BU of 8bx8 by Molmil
In situ outer dynein arm from Chlamydomonas reinhardtii in the post-power stroke state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
Authors:Zimmermann, N.E.L, Noga, A, Obbineni, J.M, Ishikawa, T.
Deposit date:2022-12-08
Release date:2023-05-10
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (30.299999 Å)
Cite:ATP-induced conformational change of axonemal outer dynein arms revealed by cryo-electron tomography.
Embo J., 42, 2023
8BWY
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BU of 8bwy by Molmil
In situ outer dynein arm from Chlamydomonas reinhardtii in a pre-power stroke state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Calmodulin, ...
Authors:Zimmermann, N.E.L, Noga, A, Obbineni, J.M, Ishikawa, T.
Deposit date:2022-12-07
Release date:2023-05-10
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (38 Å)
Cite:ATP-induced conformational change of axonemal outer dynein arms revealed by cryo-electron tomography.
Embo J., 42, 2023
1X5E
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BU of 1x5e by Molmil
The solution structure of the thioredoxin-like domain of human Thioredoxin-related transmembrane protein
Descriptor: Thioredoxin domain containing protein 1
Authors:Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-15
Release date:2005-11-15
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The solution structure of the thioredoxin-like domain of human Thioredoxin-related transmembrane protein
To be Published
1X5D
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BU of 1x5d by Molmil
The solution structure of the second thioredoxin-like domain of human Protein disulfide-isomerase A6
Descriptor: Protein disulfide-isomerase A6
Authors:Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-15
Release date:2005-11-15
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The solution structure of the second thioredoxin-like domain of human Protein disulfide-isomerase A6
To be Published
1MEK
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BU of 1mek by Molmil
HUMAN PROTEIN DISULFIDE ISOMERASE, NMR, 40 STRUCTURES
Descriptor: PROTEIN DISULFIDE ISOMERASE
Authors:Kemmink, J, Darby, N.J, Dijkstra, K, Nilges, M, Creighton, T.E.
Deposit date:1996-04-16
Release date:1997-04-21
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structure determination of the N-terminal thioredoxin-like domain of protein disulfide isomerase using multidimensional heteronuclear 13C/15N NMR spectroscopy.
Biochemistry, 35, 1996
6ALI
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BU of 6ali by Molmil
Solution NMR structure of a putative thioredoxin (ECH_0218) in the oxidized state from Ehrlichia chaffeensis, the etiological agent responsible for human monocytic ehrlichiosis. Seattle Structural Genomics Center for Infectious Disease target EhchA.00546.a
Descriptor: Thioredoxin
Authors:Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-08-08
Release date:2017-09-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution NMR structures of oxidized and reduced Ehrlichia chaffeensis thioredoxin: NMR-invisible structure owing to backbone dynamics.
Acta Crystallogr F Struct Biol Commun, 74, 2018
2HSY
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BU of 2hsy by Molmil
Solution structure of Thioredoxin 2 from Saccharomyces cerevisiae
Descriptor: Thioredoxin II
Authors:Amorim, G.C, Valente, A.P, Almeida, F.C.L.
Deposit date:2006-07-24
Release date:2007-03-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR solution structure of the reduced form of thioredoxin 2 from Saccharomyces cerevisiae
J.Biomol.Nmr, 38, 2007
1MDK
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BU of 1mdk by Molmil
HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN NFKB (RESIDUES 56-68 OF THE P50 SUBUNIT OF NFKB)
Descriptor: TARGET SITE IN HUMAN NFKB, THIOREDOXIN
Authors:Clore, G.M, Qin, J, Gronenborn, A.M.
Deposit date:1995-02-27
Release date:1995-06-03
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Structure, 3, 1995
1MDI
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BU of 1mdi by Molmil
HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN MUTANT HUMAN THIOREDOXIN AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN NFKB
Descriptor: TARGET SITE IN HUMAN NFKB, THIOREDOXIN
Authors:Clore, G.M, Qin, J, Gronenborn, A.M.
Deposit date:1995-02-27
Release date:1995-06-03
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Structure, 3, 1995
2L59
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BU of 2l59 by Molmil
Solution Structures of Oxidized and Reduced Thioredoxin C from M. tb
Descriptor: Thioredoxin
Authors:Olson, A.L, Cai, S, Sem, D.S.
Deposit date:2010-10-28
Release date:2011-10-26
Last modified:2013-04-03
Method:SOLUTION NMR
Cite:Solution structures of Mycobacterium tuberculosis thioredoxin C and models of intact thioredoxin system suggest new approaches to inhibitor and drug design.
Proteins, 81, 2013
1TOF
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BU of 1tof by Molmil
THIOREDOXIN H (OXIDIZED FORM), NMR, 23 STRUCTURES
Descriptor: THIOREDOXIN H
Authors:Mittard, V, Blackledge, M.J, Stein, M, Jacquot, J.-P, Marion, D, Lancelin, J.-M.
Deposit date:1996-05-30
Release date:1996-12-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:NMR solution structure of an oxidised thioredoxin h from the eukaryotic green alga Chlamydomonas reinhardtii.
Eur.J.Biochem., 243, 1997
2RUE
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BU of 2rue by Molmil
Solution structure of the a' domain of thermophilic fungal protein disulfide (oxidized form, 303K)
Descriptor: Protein disulfide-isomerase
Authors:Inagaki, K, Satoh, T, Kato, K.
Deposit date:2014-03-27
Release date:2015-05-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Redox-coupled structural changes of the catalytic a' domain of protein disulfide isomerase.
Febs Lett., 589, 2015
2L4Q
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BU of 2l4q by Molmil
Solution Structures of Oxidized and Reduced Thioredoxin C from M. tb
Descriptor: Thioredoxin
Authors:Olson, A.L, Cai, S, Sem, D.S.
Deposit date:2010-10-12
Release date:2011-10-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structures of Mycobacterium tuberculosis thioredoxin C and models of intact thioredoxin system suggest new approaches to inhibitor and drug design.
Proteins, 81, 2013

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