6GDG

Cryo-EM structure of the adenosine A2A receptor bound to a miniGs heterotrimer

Summary for 6GDG

• Entry DOI: 10.2210/pdb6gdg/pdb
• EMDB information: 4390
• Descriptor: TrxA,Adenosine receptor A2a, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: g-protein coupled receptor, adenosine, gpcr, a2a receptor, membrane protein
• Biological source: Escherichia coli; More
• Total number of polymer chains: 5
• Total formula weight: 144182.65

Authors

Garcia-Nafria, J.,Lee, Y. (deposition date: 2018-04-23, release date: 2018-05-16, Last modification date: 2019-12-18)

• Primary citation: Garcia-Nafria, J.,Lee, Y.,Bai, X.,Carpenter, B.,Tate, C.G.; Cryo-EM structure of the adenosine A2Areceptor coupled to an engineered heterotrimeric G protein.; Elife, 7:-, 2018; PubMed: 29726815; DOI: 10.7554/eLife.35946

Experimental method

ELECTRON MICROSCOPY (4.11 Å)